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BERLIN, June 17 (Xinhua) -- German authority said on Friday first case of human spreading deadly E. coli is detected, as death toll increases to 39 worldwide.A woman working in a kitchen of a catering company was infected by E. coli from sprouts, though she didn't fall ill immediately, said Harald Kehlborn, a spokesman for the consumer protection ministry of German state Hesse.Then she spread E. coli unconsciously to another 20 people through the food she prepared, said Kehlborn.The woman later developed serious complication of hemolytic- uremic syndrome (HUS), which causes failure of kidney and nervous system.According to the data of the Robert Koch Institute, Germany's national disease control centre, the number of people who are infected has reached 3,408 in Germany and 798 people have fallen into HUS, while the infection speed is slowing down.

WASHINGTON, July 5 (Xinhua) -- Adhering to a healthy lifestyle, including not smoking, exercising regularly, having a low body weight and eating a healthy diet, appears to lower the risk of sudden cardiac death (SCD) in women, according to a study to be published Wednesday in the Journal of the American Medical Association."Sudden cardiac death (defined as death occurring within one hour after symptom onset without evidence of circulatory collapse) accounts for more than half of all cardiac deaths, with an incidence of approximately 250,000 to 310,000 cases annually in the United States," the authors write as background information in the study.Using data collected as part of the Nurses' Health Study, Stephanie Chiuve, of Brigham and Women's Hospital and Harvard Medical School, and colleagues examined the association between a healthy lifestyle and risk of SCD.A total of 81,722 women who participated in the Nurses' Health Study from June 1984 to June 2010 were included in the new study, and lifestyle factors were assessed via questionnaires every two to four years. A low-risk lifestyle was defined as not smoking, having a body mass index (BMI) of less than 25, exercise duration of 30 minutes/day or longer, and consuming a diet closely related to a Mediterranean-style diet (emphasizes high intake of vegetables, fruits, nuts, legumes, whole grains and fish, with moderate alcohol intake).During the 26 years of follow-up, there were 321 cases of SCD among women (average age 72 years at the time of the SCD event) in the study. All four low-risk factors were significantly and independently associated with a lower risk of SCD. Not smoking, exercising and eating a healthy diet each were inversely associated with risk of SCD. BMI also was associated with the risk of SCD, with women having a BMI between 21 and 24.9 at lowest risk.Women at low risk for all four lifestyle factors had a 92 percent lower risk of SCD when compared with women at low risk for none of the four lifestyle factors."In this cohort of female nurses, adherence to an overall healthy lifestyle was associated with a lower risk of SCD and may be an effective strategy for the prevention of SCD," the authors write.

LOS ANGELES, July 18 (Xinhua) -- U.S. scientists have proven that oncogenes can change normal cells into stem-like cells, paving the way to a safer and more practical approach to treating diseases like multiple sclerosis and cancer with stem cell therapy.In a collaborative study, researchers from the Keck School of Medicine of the University of Southern California (USC), and the Children's Hospital of Orange County (CHOC) in California and Good Samaritan Hospital Medical Center in New York have successfully converted human skin cells into brain cells by suppressing the expression of p53, a protein encoded by a widely studied oncogene. This suggests that p53 mutation helps determine cell fate -- good or bad -- rather than only the outcome of cancer.Oncogenes are generally thought to be genes that, when mutated, change healthy cells into cancerous tumor cells.Study findings were appearing Monday on the website of the American Association for the Advancement of Science (AAAS)."The reality may be more complicated than people think," said Jiang F. Zhong, Ph.D., assistant professor of pathology at the Keck School. "What is a stem cell gene? What is a cancer gene? It may be the same thing.""When you turn off p53, people think the cell becomes cancerous because we tend to focus on the bad thing," Zhong said. "Actually, the cell becomes more plastic and could do good things, too. Let's say the cell is like a person who loses his job (the restriction of p53). He could become a criminal or he could find another job and have a positive effect on society. What pushes him one way or the other, we don't know because the environment is very complicated."Stem cells can divide and differentiate into different types of cells in the body. In humans, embryonic stem cells differentiate into three families, or germ layers, of cells. The reasons why and how certain stem cells differentiate into particular layers are not clearly understood. However, from those layers, tissues and organs develop. The endoderm, for example, leads to formation of the stomach, colon and lungs, while the mesoderm forms blood, bone and heart tissue. In its study, Zhong's team examined human skin cells, which are related to brain and neural cells from the ectoderm.When p53 was suppressed, the skin cells developed into cells that looked exactly like human embryonic stem cells. But, unlike other man-made stem cells that are "pluripotent" and can become any other cells in the body, these cells differentiated only into cells from the same germ layer, ectoderm."IPSCs (induced pluripotent stem cells) can turn into anything, so they are hard to control," Zhong said. "Our cells are staying within the ectoderm lineage."Zhong said he expects that suppressing other oncogenes in other families of cells would have the same effect, which could have critical significance for stem cell therapy. Future research should focus on determining which genes to manipulate, Zhong said.The study is slated to appear in the Proceedings of the National Academy of Sciences later this month, according to AAAS.

BEIJING, Sept. 26 (Xinhuanet) -- Although it is home to traditional Chinese medicine (TCM), China must do much more to improve its academic research capacity for acupuncture, a form of TCM, to take the lead worldwide on both the academic and clinical sides.At present, among all academic theses on acupuncture indexed by the Science Citation Index (SCI), a leading world thesis index system, only 5 percent are from the Chinese mainland, according to Wang Linpeng, the director of the acupuncture and moxibustion center of the Beijing Hospital of Traditional Chinese Medicine, which is affiliated with the Capital Medical University.Although Chinese acupuncturists absolutely excel worldwide in clinical practice, "they are not as good as their foreign peers in academic capacity, particularly Western-style research methods and lab experiment design," he told China Daily on Friday during the 2011 International Symposium on Acupuncture. A patient suffering from facial paralysis receives acupuncture treatment at a hospital in Nanjing, the capital of Jiangsu province, on Dec 6, 2010.Studies by TCM practitioners - including acupuncturists - largely focus on their area of specialization, and few are in line with global interest in the medical science that has been proven effective over thousands of years, he said."Chinese TCM practitioners are very good at treating conditions, but they are clumsy at showing how and why it really works in an internationally accepted 'language' and 'manner'," said Gao Sihua, chancellor of the Beijing University of Chinese Medicine."It's especially true in TCM circles, where few Chinese practitioners would regularly follow international academic articles and research trends," Wang said.Measured by the number of articles on acupuncture indexed by SCI, the US and European countries lead globally, he said.

WASHINGTON, Aug. 31 (Xinhua) -- Astronomers using NASA's Chandra X-ray Observatory discovered the first pair of supermassive black holes in a spiral galaxy similar to the Milky Way, NASA announced Wednesday.Approximately 160 million light years from Earth, the pair is the nearest known such phenomenon.The black holes are located near the center of the spiral galaxy NGC 3393. Separated by only 490 light years, the black holes are likely the remnant of a merger of two galaxies of unequal mass a billion or more years ago.Both of the supermassive black holes are heavily obscured by dust and gas, which makes them difficult to observe in optical light. Because X-rays are more energetic, they can penetrate this obscuring material. Chandra's X-ray spectra show clear signatures of a pair of supermassive black holes."If this galaxy weren't so close, we'd have no chance of separating the two black holes the way we have," said Pepi Fabbiano of the Harvard-Smithsonian Center for Astrophysics, who led the study that appeared Wednesday in on-line issue of the journal Nature. "Since this galaxy was right under our noses by cosmic standards, it makes us wonder how many of these black hole pairs we've been missing."Previous observations in X-rays and at other wavelengths indicated that a single supermassive black hole existed in the center of NGC 3393. However, a long look by Chandra allowed the researchers to detect and separate the dual black holes. Both black holes are actively growing and emitting X-rays as gas falls towards them and becomes hotter.When two equal-sized spiral galaxies merge, astronomers think it should result in the formation of a black hole pair and a galaxy with a disrupted appearance and intense star formation. A well-known example is the pair of supermassive black holes in NGC 6240, which is located about 330 million light years from Earth.However, NGC 3393 is a well-organized spiral galaxy, and its central bulge is dominated by old stars. These are unusual properties for a galaxy containing a pair of black holes.