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A large fire broke out early Friday at a refinery in Philadelphia, the city fire department told CNN.The fire started at Philadelphia Energy Solutions between 3 and 4 a.m., according to CNN affiliates.Residents reported several explosions that were felt in South Jersey and Delaware County, Pennsylvania, according to CNN affiliate 344

SEATTLE, Wash. – For most sports enthusiasts immersing themselves in the roar of a stadium is the best part of fan experience. This year, numerous NFL teams are tailoring their venues for a very distinct group of spectators – those who otherwise might not be able to join in. While the sights and sounds of attending a sporting event can make it an unforgettable experience, Traci Schneider knows it’s not for everyone. “For a lot of people that can be really, really overwhelming.” It’s why more and more teams are adding sensory rooms to their venues. We were given access to one at CenturyLink Field, home to the Seattle Seahawks. “This is a place to go and a place to be safe and kind of just a little break to get away from it all,” explained Schneider. “So, any fan can come in here.” Schneider’s 17-year-old son Ben has autism. “Sensory issues are a big challenge for him, and I know what that looks like as a mom,” said Schneider. “And you want to make the world a little bit easier for your kids to navigate.” She helped provide input for this space, because not only is she a mom of a child with autism, but she’s also married to the Seahawks’ general manager. Schneider says the room is meant to help people with autism, anxiety, PTSD and other sensory disorders. “We still have a TV so people can still watch what’s happening out on the field,” Schneider said. The Seahawk’s room features dimmable overhead lighting, hooded chairs, a calming bubble wall and a fiber-optic waterfall curtain. “They slowly change colors and they’re meant to be touched,” Schneider said. All of the items help to calm a person. In addition to the sensory room, the Seahawks are the first to offer autism kits that include noise cancelling headphones and information on when the loudest moments in the game are expected to happen, including pyrotechnics. Schneider says the ultimate goal is to provide a safe space for anyone who may need a temporary reprieve without making them feel like they’re missing out. “So just knowing that that is supporting our fans and making them feel welcome. I think is just huge.” 2134

A Las Vegas woman who has been charged with murder in regards to an incident in which an elderly man was pushed off a public bus has been released on bail.Cadesha Bishop, 25, was released from jail on 0,000 bond on Wednesday. She's due back in court on May 23.Bishop was charged with murder earlier this week following the death of Serge Fournier. The 74 year old man died earlier this month after he was pushed off a public bus in Las Vegas on March 21.Fournier initially refused medical treatment but went to the hospital later that day. On May 3, police were notified that the man had died from his injuries. The coroner ruled his death was a result of the injuries he received from being pushed.Homicide detectives later determined that Fournier had died from injuries sustained after being pushed. 818

A Denver family is trying to raise million in order to cure their son with a rare genetic disease. Doctors told Amber Freed that her 2-year-old son is one of 34 people in the world to have this rare neurological genetic disease. “The disease is so rare, it doesn’t even have a name,” Freed said. “It’s called SLC6A1, because that is the gene that it effects.” The disease causes Maxwell to have trouble moving and communicating, and soon it will only get worse. “The most debilitating part of the disease will begin between the ages of 3 and 4,” Freed said. “So, we are in a fight against time.”Maxwell has a twin sister named Riley. “I noticed early on that Maxwell wasn’t progressing as much as Riley,” Freed said. “I noticed he couldn’t use his hands. The doctors told me that every baby can use their hands. That’s when I realized there was something wrong with him.”After multiple visits to the doctor, Freed was able to find a genetic specialist to give Maxwell a diagnosis. “He looked at me and said, ‘Something is very wrong with your son. I don’t know if he’s going to live,’” Freed said. “My soul was just crushed. It was a sadness I didn’t even know existed on earth. You never think something like this could happen. I left my career, and I had no other choice but to create my own miracle and to find a treatment forward to help Maxwell and all those others like him.” Freed searched for scientists trying to create a cure, which she found at the University of Texas Southwestern Medical Center in Dallas. “We’re working with diseases where kids are born with a defective gene,” said Steven Gray, an associate professor at UTSW in pediatrics. “Our approach is to replace that gene to fix the condition at the level of their DNA. We’re taking the DNA that those patients are missing and packaging that into a virus and use that virus as a molecular delivery truck to carry those genes back in their body and fix their DNA.” “It’s a rare disease, no one has ever heard of it,” Freed said. “But one rare disease messed with the wrong mother.” Freed said she has raised million to help with research for the cure and will need an additional million, in order to let Maxwell and many others continue to enjoy life. “I want Maxwell to have every opportunity that children should have in this life,” Freed said. “When he is having a good day, I just try and soak him in as much as I can. We don’t take anything for granted in this house.” If you want to help donate for the cure, you can do so by visiting 2535

A company that claims to have the first drug to slow mental decline from Alzheimer’s disease made its case to scientists Thursday but left them sharply divided over whether there’s enough evidence of effectiveness for the medicine to warrant federal approval.Excitement and skepticism have surrounded aducanumab since its developers stopped two studies earlier this year because it didn’t seem to be working, then did a stunning about-face in October and said new results suggest it was effective at a high dose.During Thursday’s presentation at an Alzheimer’s 573