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CLEVELAND — Ohio State head football coach Urban Meyer will retire after the Rose Bowl on Jan. 1, Ohio State confirmed in a news release on Tuesday.Meyer, who led the Buckeyes to their third Big Ten title game on Saturday, is believed to be stepping down due to health reasons. 295

Could the no-calorie sweetener you rely on to replace sugar in your diet actually cause weight gain instead of the weight loss you were expecting?The answer may be yes, according to a new study."Artificial sweeteners are not risk-free," said Brian Hoffmann, assistant professor in the Department of Biomedical Engineering at the Medical College of Wisconsin and Marquette University, and a lead author of the study. "They are a very controversial topic when it comes to health and nutrition ... but they're so prevalent in society that I think we owe it to ourselves to try and figure out what's actually going on."Hoffmann presented his new research Sunday at the annual?Experimental Biology meeting in San Diego. Relying on rats and human cell cultures, his team identified a number of pathways linking artificial sweeteners with metabolic changes at the genetic level that could lead to diabetes and obesity. Specifically, the researchers found that three weeks of exposure to aspartame and acesulfame potassium -- two artificial sweeteners frequently combined in products such as Equal -- altered the expression of certain genes responsible for lipid metabolism in the cells of both rats and humans."Aspartame had some significant changes, and one of those was an increase in lipids in the bloodstream and a decrease in a biomolecule that is involved in clearing (lipids) from the bloodstream. And we saw the exact same thing with the acesulfame potassium," Hoffmann said."We then took those particular sweeteners and put them on endothelial cells -- the cells that line the blood vessels and would be exposed to them in the body -- and we detected a marked dysfunction, suggesting why sweeteners and diet soda have been linked to potential cardiovascular problems," he added.What was perhaps most surprising, according to Hoffmann, was that these metabolic changes did not occur in the presence of natural sugars such as glucose and fructose. This suggests that artificial sweeteners could contribute to metabolic disorders such as diabetes and obesity by an entirely different mechanism than natural sugars, he said.Artificial sweeteners appear to contribute to metabolic disorders by altering the activity of certain genes responsible for the breakdown of macromolecules such as fats and proteins, Hoffmann said. This is different from normal sugars, which contribute to cardiovascular disease through insulin resistance and by damaging the cells lining the body's blood vessels."People are generally consuming non-nutritive sweeteners believing they are a 'healthy choice,' but this may not be true," said research scientist Meghan Azad of the University of Manitoba in Winnipeg, who was not involved in the new study."This is especially important given the widespread and increasing consumption of artificial sweeteners in the general population and the increasing use of artificial sweeteners in our food supply," said Azad, who has authored a paper that reviewed a number of studies on the potential downside of artificial sweeteners on weight and health.According to Azad, over 40% of adult Americans consume no-cal sweeteners on a daily basis, and studies that measure the sweeteners in blood and urine show that many people who report not using artificial sweeteners are unknowingly consuming them.It's the latest assault in the ongoing debate over artificial sweeteners and their impact on health -- a debate that began when one of our most popular foods, sugar, turned sour in terms of health. 3527

Congress passed a bipartisan bill to address the opioid epidemic, and this week the president signed it into law. It's one of the few things that brought Democrats and Republicans together.“Opioids is definitely an issue where there's a lot of bipartisan agreement,” says Republican strategist Brian Bartlett. “We saw the Senate pass their version 99-1. The House also overwhelmingly passed legislation back in June the first time around to address this issue.”Democratic strategist Brandon Neal agrees, saying the issue of opioids is a bipartisan issue affecting everyone.On average, a person dies from an opioid overdose every eight minutes, according to the CDC.“Right now, we're in a point in our society where every average person, everyday person, is affected by this,” Neal says. “So, one pill kills.”The impact of the problem is so big, it forced both political parties to come together to pass a bill that will boost programs to treat addictions, keep a closer eye on prescriptions and promote research to find new drugs that are not as addictive.“I think the next step is to start enacting some of the changes this legislation offered, because in a lot of ways, this was a comprehensive bill, but we need to see what's going to be most effective and what works,” Bartlett says.Just this week, there was a small glimmer of hope. Early data shows the number of overdose deaths are beginning to level off and have even slightly dropped, according to Health and Human Secretary Alex Azar.“The seemingly relentless trend of rising overdose deaths seems to be finally bending in the right direction,” Azar says. 1623

CLEVELAND — A popular beer joint in Cleveland is closing its doors to keep its employees safe because some customers refuse to follow rules on mask-wearing and social distancing.Forest City Brewery made the announcement on Facebook Tuesday morning."It pains us to inform you that we will be closed to the public as of 7/22/20. We did our very best to do the right thing and protect the health of our employees, our customers and our neighborhood for the past 2 months," the establishment said on Facebook.According to the brewery, employees, "had a hard time dealing with people who refuse to wear masks, social distance, or follow the rules set forth by the city of Cleveland and the State of Ohio."The brewery stated that even though its doors are closing, it will continue to serve the community by selling cans and growlers in the future."Until then, stay safe Cleveland, we will miss you and see you when it is safe again, and people start acting in a responsible manner," the brewery stated.This article was written by Drew Scofield for WEWS. 1056

Critics are calling Sinclair's promos pro-Trump propaganda. Now the company is defending the initiative, and calling it something much more mundane: A "corporate news journalistic responsibility promotional campaign."Sinclair, America's largest operator of local TV stations, is in the spotlight after a controversial promo video went viral over the weekend.Some staffers say they're embarrassed by the promos and concerned about their own credibility as journalists. A few local anchors and reporters are even reacting publicly, risking the ire of management.But Sinclair senior vice president of news Scott Livingston is defending the promos as a "well-researched journalistic initiative focused on fair and objective reporting."In an internal memo obtained by CNNMoney, Livingston slammed what he called "misleading, often defamatory stories" about the company. (The full memo is below.)Last month, at Livingston's direction, anchors at Sinclair's stations were required to read a script decrying "fake stories" and biased news coverage. Some of the language echoes President Trump's anti-media messaging. And it's written to make it sound like the opinion of the local anchors, when in fact it's a mandate from management.Concerned journalists contacted CNNMoney about the promos last month. When the promos started airing, the Deadspin blog produced a video compilation of the exact same script being read by anchors across the country, reiterating the robotic and manipulative nature of the message. 1518