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AstraZeneca is the latest drugmaker to announce promising Phase 3 trial results from its COVID-19 vaccine candidate.On Monday, AstraZeneca said its two-shot vaccine candidate has been 90% effective thus far along with no safety concerns.“These findings show that we have an effective vaccine that will save many lives," said Professor Andrew Pollard, the chief executive of the study. Excitingly, we’ve found that one of our dosing regimens may be around 90% effective and if this dosing regime is used, more people could be vaccinated with planned vaccine supply. Today’s announcement is only possible thanks to the many volunteers in our trial, and the hard working and talented team of researchers based around the world.”The company added in its press release that its vaccine candidate offers two distinct advantages over vaccines made by Pfizer and Moderna — it's cheaper to produce, and does not need to be stored in ultra-cold conditions before use.AstraZeneca added that the company would "immediately" prepare regulatory paperwork to seek Emergency Use Listing status from the World Health Organization.AstraZeneca is just the latest drug company to report encouraging results from its COVID-19 vaccine candidate.Last week, Pfizer said it had submitted Emergency Use Authorization paperwork to the Food & Drug Administration (FDA) after a final analysis of its vaccine candidate proved to be 95% effective in preventing COVID-19. The FDA is expected to approve the drug in the coming weeks.Moderna has also said that early results show its vaccine candidate to be 95% effective, and is on track to have the drug approved for Emergency Use Authorization by the end of the year.AstraZeneca, Pfizer and Moderna are all shattering records for vaccine development. The three vaccines are all on track to be approved for widespread use in uder a year. Typically, it takes several years for a vaccine to go from development to approval.The announcement comes as COVID-19 is spreading around the world at a rate not previously seen since the pandemic began. And while all three companies are pre-producing their vaccines in the hope that it will be approved, health experts warn that they won't be widely available until spring 2021. 2247

Authorities in Costa Rica say that a body has been found on the Airbnb property where missing Florida woman, 36-year-old Carla Stefaniak, was staying.Costa Rica's Judicial Investigation Agency (OIJ) tells WFTS that the body was buried in a mountainous area located in the back of the property, less than 200 feet away from where Stefaniak had been staying. OIJ agents had been searching the area with specialized dogs. At this time, authorities have not been able to confirm that the body is Stefaniak.In Spanish, Walter Espinoza, the director general of the OIJ said, “the body was in a state of decomposition but the preliminary observation does verify the body is a woman.”In a press conference on Monday, Espinoza said that biological fluids consistent with blood were discovered inside the Airbnb property. The blood has been sent to labs for testing.The body cannot be positively identified by officials until an autopsy is performed.Stefaniak hasn't been seen or heard from since Tuesday, November 27. She traveled to Costa Rica with her sister-in-law, April Burton, on November 22 to celebrate her birthday. Burton flew back on November 27. Stefaniak had plans to return to the United States on November 28, bound for Florida, but never arrived for her flight. She checked into her Airbnb, located at Calle Hoja Blanca in San Antonio de Escazú, for one night on November 27. According to Burton, the last thing they knew about Stefaniak was that she was inside that Airbnb on the night of November 27. The last time Burton spoke to Stefaniak, she told her that it was raining crazy and the power went out. She continued with, "it's pretty sketchy here," according to Burton.The final photograph Stefaniak sent family members was from inside the Airbnb. Family members shared the image with WFTS, seen below.</p><p>"The guards (at the apartment complex that housed the Airbnb) told us that she left at 5 in the morning with all of her bags and got into an Uber. She wouldn’t do that, her flight was at 1:30 p.m. She’s never been early for anything in her life she wouldn’t leave to go to the airport at 5:30 a.m.," Burton said.The Airbnb listing for "Villa Buena Vista" has since been removed from Airbnb's website.WFTS spoke to Airbnb officials, who say they have reached out to Carla's family as well as the FBI, OIJ and the local embassy.Stefaniak's brother flew down to Costa Rica on Friday to search for his sister. Her father flew down to Costa Rica on Monday afternoon.This is a developing news story and will be updated as more information becomes available. 2718

At a Monday afternoon hearing regarding records from the Florida Department of Children and Families, a judge ruled a three-page confidential investigative summary and 19 pages of background materials could be released regarding Nikolas Cruz.FULL COVERAGE: Parkland school shootingNames of non-DCF employees listed in those pages will be redacted, but their titles won't be.The records were released later Monday, showing the following: ?       DCF Adult Protective Services was called on Sept. 28, 2016 to investigate allegations that Nikolas Cruz was being victimized by his caregiver -- his adoptive mother.?       Following an investigation involving mental health counselors, school personnel, and law enforcement who had contact with Cruz, DCF found no indicators of abuse or neglect as alleged; 854

At 3 p.m. ET on Monday, November 26, a group of researchers will be really sweating. The NASA InSight spacecraft will try to land on Mars.After six months of flight, the lander component of the probe will detach itself from the cruise stage and head into the atmosphere. The lander component initially looks a fair bit like the re-entry capsule used in the 1960s and 1970s for the Apollo moon missions -- sort of conical, with a smooth and flat bottom. That bottom is a crucial heat shield that is designed to protect the probe as it passes through the thin Martian atmosphere.The landing is a devilishly difficult feat. The landing capsule has to batter its way through the atmosphere. It will fly through the Martian air at an initial speed of 12,300 mph, and it must hit the atmosphere at an angle of precisely 12 degrees. Any shallower, and the probe will bounce off into deep space. Any steeper, and the probe will burn itself up in a spectacular and fiery death. The probe will first touch the atmosphere six minutes and 45 seconds before landing. During this phase, it will experience acceleration 12 times that of the Earth's gravity. Were the probe a 150-pound human, during the flaming descent, it would weigh nearly a ton.About 3? minutes after the probe hits the atmosphere, a parachute will deploy, slowing down the probe even more. Fifteen seconds later, explosives will blow the heat shield off, exposing the actual InSight probe hidden inside. Ten seconds after the heat shield falls away, the probe will extend its legs, much like an airplane extends its wheels before touching down.The probe will fall for an additional two minutes attached to the parachute and protected by its conical shell. About 45 seconds before InSight lands, it will drop out of the shell and fall toward the surface. As soon as it leaves the shell, its landing rockets will ignite.The actual InSight probe looks a little bit like the Apollo moon lander, with three legs to support it and a boxy top. The rockets will slow it further and stop any remaining horizontal motion. Then, about 15 seconds before touchdown, the InSight probe will descend at a speed of 8 feet per second, before hopefully touching down gently on the Martian surface.The entire landing sequence will take about seven minutes to occur. A radio signal from Mars to Earth currently takes about eight minutes and seven seconds to get here. So the complete landing process will take place before we find out if it was successful. It will be done automatically, entirely by the probe itself. For the scientists and engineers who designed InSight, this is called "seven minutes of terror."And they are right to be worried. Mars is a graveyard of failed probes. There have been 44 attempts by various national space agencies to land on Mars. Eighteen have been successful. Twenty-three have not. Three have achieved orbit but failed at a landing.So, what does InSight hope to achieve? Well, as it happens, a lot. But it's different than the intrepid Curiosity probe, which NASA landed in 2012. InSight will not move around. Instead, it will stay put and tell us of the interior of Mars.One thing it will do is emit radio waves that we can monitor on Earth. By making careful measurements of how the frequency of the radio waves change, we will be able to measure the degree to which Mars wobbles as it rotates. That will tell us something about the core of the planet, specifically its makeup and information on the degree to which it is molten.InSight will also deploy a seismometer to listen for marsquakes (like earthquakes, but Martian-style) and for impacts of meteors on the planet. Information gleaned from the waves the seismometer detects will tell us more about the planet's interior.The third thing InSight will do is to dig below the planet's surface. Using a jackhammer, the probe will drill down 5 meters (16 feet) into the planet and, basically, it will take the planet's temperature.There are many reasons this is interesting. Taking the temperature at that depth will allow planetary scientists to determine how much heat is escaping from Mars. More broadly, this measurement will allow a clear determination of the temperature of the planet much closer to the core.This information will tell us a lot about how Mars formed, which, in turn, will add to the information of how rocky planets, including our own Earth, typically develop.And if you're more of an explorer kind of person and not so interested in Martian geology, it will also tell us how warm the planet is at modest depths, which will tell us if there is any chance of liquid water on the planet. Perhaps obviously, if the Martian subsurface is warm enough, any buried water will be in liquid form and not ice. Finding liquid water would be the key discovery that would make Martian exploration relatively easy. A relatively recent possible discovery of a buried Martian lake was promising, but the data was not conclusive. Knowing that the ground is warm would be very comforting to possible future explorers.Exploring the solar system is the first step toward exploring the stars. The InSight probe will give us --well -- insight into whether this is something that humanity will achieve in the foreseeable future.And maybe Elon Musk's bet on him getting to Mars will become true. 5329

BAKERSFIELD, Calif. (KGTV) — A man accused of boarding a Greyhound bus in San Diego before opening fire and killing one person in the Los Angeles area pleaded not guilty in court.Anthony Devonte Williams, 33, of Capital Heights, Md., pleaded not guilty to one count of first-degree murder and five counts of attempted murder.Williams is accused of opening fire on a bus as it was traveling on Interstate 5 between Los Angeles and Bakersfield on Feb. 3. He reportedly first boarded a bus from San Diego to Los Angeles before boarding another bus in Los Angeles heading to San Francisco.Passengers say Williams was cursing and muttering incoherently before opening fire.The shooting killed 51-year-old Lurbis Elena Vence, of Molino, Colombia, according to KERO., and injured five other people.Other passengers were able to disarm Williams and forced him off the bus. 872