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LA JOLLA (KGTV): Researchers at the UC San Diego Moores Cancer Center and the La Jolla Institute of Allergy and Immunology have teamed up to find a new way to fight cancer.They've created a vaccine that can help teach the immune system how to attack only cancer cells and leave the rest of the body alone."Patients will be able to tolerate their therapy much better than they have so far on conventional approaches," says Dr. Stephen Schoenberger from the La Jolla Institute.Each vaccine is highly personalized to the patient. According to a release from UC San Diego, the vaccines "defines the neoantigens – foreign protein fragments recognized by the immune system – in a patient’s cancer. With neoantigens identified, the team can identify peptides – strings of amino acids – that can be used to create a vaccine to stimulate a protective immune system response."Simply put, the new vaccine takes information from a patient's immune system and the tumor and uses it to help white blood cells to fight it."We're giving them life and giving them hope," says Dr. Schoenberger.The first patient in the clinical trial is Tamara Strauss. She was diagnosed with pancreatic cancer in 2015 and went through chemotherapy and surgery."It was brutal," says Strauss. "It's been three and a half years of hell."Strauss' parents helped fund the clinical trial with a million donation. She says she feels fortunate they could do that, but also hopeful that it helps others down the road."I really pray that this vaccine and personalized form of treatment really does change the paradigm of cancer treatment," says Strauss.During the trial, ten patients will get three doses of the vaccine. They'll also be on Keytruda, an immune system boosting drug for up to two years. Their health will be monitored for five years to determine the vaccine's effectiveness. 1871
LA JOLLA, Calif. (KGTV) — Coast Boulevard in La Jolla was shut down Thursday, and will remain temporarily closed, as city crews began emergency construction to stabilize a nearby cave.The city closed Coast Blvd. late Thursday to begin an emergency project to stabilize Cook's Crack after geology experts discovered a zone of weakness in the cave, which is located underneath the street.During a press conference, crews said the concern is an outright collapse of the section of road over the cave. Currently, the weakness "is not a slow settlement" and could fail if erosion happens underneath the street. Much of the dense rock had eroded, and now sand and roots were showing through from underneath.As part of the project, sections of Cave St. and Coast Blvd. will be temporarily closed to traffic for about six weeks. The city said it will make accommodations for nearby residents and business affected by the closure.Officials said the discovery came as the city assessed repairs to Coast Blvd."They said there's been some shift in the road itself," David Heine, owner of nearby Brockton Villa Restaurant, said. "The busiest two weeks of summer, literally ... Obviously safety's the number one concern for any city, and we respect that." Heine said crews are allowing pedestrians to continue to walk through the area.The city called in crews from Texas, who drove in overnight to take over the project. Friday, the crews began drilling into the street above to locate some of the weakest points. Eco-friendly polyurethane will be used to shore up those weak points, crews say.Cook's Crack is located in the area between La Jolla Cove and the popular Cave Store. The section of coastline is populated by several small caves that tourists can explore through an entrance in The Cave Store or kayaking nearby.The section of Coast Blvd. over the cave is a popular route to visit the cove and coastline, as well as restaurants that dot the street. 1954
JAMUL (CNS) - A small plane landed in thick grass southeast of Jamul Casino in Jamul Wednesday night, but no one was injured.Deputies received a call of a downed plane about 7:50 p.m. off Campo Road, according to Lt. Glen Twyman of the San Diego County Sheriff's Department. The type of plane was not released.It was not immediately clear if the plane made an emergency landing or crashed, but neither occupant was injured.Fire crews remained on scene after the crash to prevent any of the nearby dry grass from catching on fire, Twyman said. 550
Kim Kardashian West, Demi Lovato, Kerry Washington, Leonardo DiCaprio, Katy Perry and others will be staying off Facebook and Instagram Wednesday, September 16 as part of a coordinated week-long campaign about misinformation on the platform.“I love that I can connect directly with you through Instagram and Facebook, but I can’t sit by and stay silent while these platforms continue to allow the spreading of hate, propaganda and misinformation - created by groups to sow division and split America apart – only to take steps after people are killed,” Kardashian posted to Facebook Tuesday afternoon, with an orange and white image reading “stop hate" and the #StopHateforProfit tag. 692
LA JOLLA, Calif. (KGTV) – A man who reportedly tried to hit his girlfriend with a pickaxe was taken into custody after a standoff at a La Jolla Shores home.At around 10:40 a.m. Thursday, San Diego police officers were called to a house in the 2500 block of Ellentown Road after receiving reports of a domestic violence incident.10News learned a man inside reportedly threatened his girlfriend with a pickaxe, prompting her to leave. The unidentified man remained inside and refused police orders to come out."When we first got here, he was not communicating with us, he was just inside the house, yelling and screaming and banging against the wall," said SDPD Captain Tina Williams.While officers tried to persuade him to surrender, sections of Ellentown Road were shut down due to the police activity.At times the man appeared in the windows of the home holding the ax and knives, according to Williams. He also started a debris fire on top of his stove, sending smoke billowing from the house. Shortly after 1 p.m., the man went to the backyard, where police took him into custody without incident, according to Williams.The man was booked on suspicion of attempted assault with a deadly weapon and felony domestic violence battery.The victim was not seriously injured.Williams said the incident was not the first time police had been called to the house. "Earlier this week, we did respond out here... he was out in the middle of the street causing an altercation," she said. He was gone by the time police arrived. 1562
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