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BEIJING, Aug. 22 (Xinhuanet) -- Researchers have discovered how a human egg captures an incoming sperm for fertilization, paving the way to help couples suffering from infertility, according to media reports on Monday.An international team of researchers found that a sugar chain known as the sialyl-lewis-x sequence (SLeX) makes the outer coat of the egg “sticky,” which has proven to be helpful in binding the egg and the sperm.As a result, this observation has filled in a huge gap in the understanding of fertility and provides hope for ultimately helping couples who currently cannot conceive.Scientists and doctors know that a sperm identifies an egg when proteins on the head of the sperm match and bind to a series of specific sugars in the egg’s outer coating. With a successful match of proteins, the outside surfaces of the sperm and egg then bind together before merging, which is then followed by delivery of sperm’s DNA into egg.To identify this molecules, the researchers used ultra-sensitive mass-spectrometric imaging technology to observe and identify which molecules are most likely to be key in the binding process.They experimented with a range of synthesised sugars in the laboratory and found that it is SLeX that specifically binds sperm to an egg.According to the World Health Organisation, infertility affects about 15 percent of reproductive-aged couples around the world and almost one in every seven couples in Britain has problems conceiving a child for various reasons.
JOHANNESBURG, June 1 (Xinhua) -- An estimated 2 million adolescents ages 10 to 19 are living with HIV, with 86 percent of them from sub-Saharan Africa, according to a global report on HIV prevention launched in Johannesburg on Wednesday.For the first time, the world gets to see the number of adolescents between the ages of 10 to 19 living with HIV in the report named Opportunity in Crisis: Preventing HIV from early adolescence to young adulthood.The report is a jointly publication by the United Nations Children's Fund (UNICEF), UNAIDS, the United Nations Educational, Scientific and Cultural Organization (UNESCO), the United Nations Population Fund (UNFPA), the International Labor Organization (ILO) , the World Health Organization (WHO) and World Bank.According to the report, people aged 15-24 accounted for 41 percent of new infections over the age of 15 in 2009. Worldwide, an estimated 5 million young people in that age group were living with HIV in 2009. Most of them live in sub-Saharan Africa. Globally, young women make up more than 60 percent of all young people living with HIV. In sub-Saharan Africa that rate jumped to 72 percent.Despite these challenges, the report acknowledges that some progress has been made in preventing new infections among young people."In many high-burden countries, HIV prevalence and incidence have declined among young people. While in 2001 there were 5.7 million young people living with HIV, the figure stands at 5 million (in 2009)," said the UNICEF eastern and southern Africa regional director, Elhadj As Sy, at the media briefing.He pointed that sexual transmission and injection drug use remain the major modes of transmission of HIV among young people. Early sexual debut, early pregnancy and early experiences with drug use all raise risks for HIV infection.The report reveals that unemployment and poverty are reported as the main reasons young people enter the sex trade. Worldwide, many young people driven by economic pressure, exploitation, social exclusion and lack of family support turn to commercial sex and injecting drug use.In 2001, the world made a commitment to reduce the prevalence of HIV among young people by 25 percent by 2010. The actual reduction achieved (from 5.7 million to 5 million) is 12 percent, and it represents less than half the target percentage."To avoid the current programming failures, we have to adopt a ' Continuum of Prevention Approach'." said Lina Mousa, deputy director of UNFPA Africa Regional Office."This continuum of prevention must be reflected in national HIV strategic plans, poverty reduction strategies and global fund proposals. This response must be developed with and for young people so that they own the response together with their communities," she added.To build this continuum of prevention for adolescents and young people, the reports outlined nine specific recommendations including providing young people with information and comprehensive sexuality education, strengthening child protection and social protection measures, engaging communities in shaping a positive social environment that promotes healthy behavior, establishing laws and policies that respect young people's rights.

SAN FRANCISCO, July 21 (Xinhua) -- Microsoft Corp. on Thursday posted strong quarterly earnings in its fourth fiscal quarter, with profit and revenue beating expectations from Wall Street analysts.For the quarter ended June 30, the world's largest software maker reported a net income of 5.87 billion U.S. dollars, or 69 cents per share, representing increases of 30 percent and 35 percent respectively when compared with the year-ago period.Revenue for the quarter was 17.37 billion dollars, up by 8 percent from the same period a year earlier.Wall Street analysts had expected a profit of 58 cents per share on a revenue of 17.23 billion dollars, according to Thomson Reuters.For the whole fiscal year, Microsoft reported a record revenue of 69.94 billion dollars, a 12 percent increase from the prior fiscal year. Net income for the year was 23.15 billion dollars, accounting for an increase of 23 percent.Among its business sectors, Microsoft Business Division revenue grew 7 percent for the fourth quarter and 16 percent for the full year. Over 100 million licenses of office 2010 have been sold so far, said the company.Primarily driven by growth in search revenue, the company's on- line services division revenue grew 17 percent for the fourth quarter and 15 percent for the full year. U.S. search share of Microsoft's search engine Bing increased 340 basis points year- over-year.Microsoft said revenue of entertainment and devices division grew by 30 percent for the quarter and 45 percent for the year.However, Windows and Windows Live revenue declined by 1 percent for the fourth quarter and decreased by 2 percent for the full year. Microsoft said estimated full-year revenue growth for the Windows division was in line with the sluggish PC market growth.
BERLIN, June 8 (Xinhua) -- The deadly strain for the E. coli outbreak was found again on cucumbers, authorities of German state Saxony-Anhalt said on Wednesday. The strain O104 was found on the scraps of cucumbers in a dustbin in the eastern city of Magdeburg, said State Health Minister Holger Paech.The dustbin belongs to a family in which three members have been ill. Paech said. The father only suffered a slight stomach upset, while the mother was once treated at a hospital and is now released. Their daughter is suffering from hemolytic-uremic syndrome (HUS), a serious complication from the infection of E. coli.However, experts were not clear about how the bacteria came to the cumbers, which have been in the dustbin for a week and a half."It is not clear and we are not able to determine how it reached there." Paech said.German authority first detected such bacteria from Spanish cucumbers on May 26, which has been overthrown by the laboratory tests in Hamburg last Tuesday.On Sunday, German State Lower Saxony issued a warning on bean sprouts as a possible source for the outbreak, which was proven to be negative on Monday.The German government has faced increasing criticism from abroad and at home for dealing with this crisis, as it has wrongly blamed the source of the infection for twice and there is a lack of coordination between different research institutes on the outbreak.John Dalli, European Union Health Commissioner, was quoted by local daily Die Welt saying "we have to rely on the experience and expertise across Europe, and even outside Europe."The Max Planck Institute for Infection Biology in Berlin also called for a federal government representative to coordinate the various government agencies which are dealing with the crisis.A federal government representative could increase cooperation between ministries and reduce mixed messages from the government, said director Stefan Kaufmann.On the same day, Germany's national disease control center, the Robert Koch Institute, said the number of infection has shown an overall decreasing trend but it is still uncertain whether the decline is due to people staying away from vegetables or to the waning of the source of infection.Until Wednesday, 25 deaths have been reported while the infection cases have increased more than 2,600 in 12 countries around the world.
SAN FRANCISCO, July 6 (Xinhua) -- Facebook on Wednesday introduced a new video calling feature powered by Skype and some improvements to the chat designs on the social networking site.According to Facebook, users can reach video calling from a new "Call" button on a friend's profile or from the chat panel after downloading a Skype application. A recipient will receive an alert that they are being called and can then accept or decline.At the press event held at Facebook headquarters in Palo Alto, California, CEO Mark Zuckerberg said the feature will begin with one-on-one video chat. Skype CEO Tony Bates, whose company has been acquired by Microsoft, said Skype is considering having its paid product within the Facebook product.The social networking company also introduced "Ad Hoc Group Chat", which enables users to start a group chat instantly without creating a group with those multiple friends at first. The new group chat feature is also available for Facebook's mobile interfaces.Facebook also introduces a sidebar that lists the people a user messages most, enabling users to chat with close friends, professional contacts or co-workers without being interrupted. The sidebar can adjust with the size of users' browser window and automatically appears when the window is wide enough.In the opening remarks at the press event, Zuckerberg confirmed that Facebook had surpassed 750 million monthly active users. He said the company had declined to announce the number earlier because it has become focused on other metrics, like how actively users are sharing information.The CEO said users are now sharing 4 billion "things" on Facebook every day, which grew at an exponential rate compared to the amount users share a year ago."Social networking is at an inflection point," said Zuckerberg, adding that he believes social networking now is more about the strength of connecting people rather than the quantity of users or ubiquity of the technology.Zuckerberg presented a graph to show how Facebook product launches have helped drive the growth of sharing. He said the social network expects more innovations from other companies involved in everything from music to communication to help drive the growth.
来源:资阳报