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The US Food and Drug Administration approved Janssen Pharmaceuticals Inc.'s esketamine on Tuesday for treatment-resistant depression; the drug is the chemical cousin of ketamine, the powerful anesthetic that has been used illegally as the club drug Special K.It will be sold as Spravato. More specifically, it's for patients who have tried at least two other medications without success, and it should be taken with an oral antidepressant."There has been a longstanding need for additional effective treatments for treatment-resistant depression, a serious and life-threatening condition," Dr. Tiffany Farchione, acting director of the Division of Psychiatry Products at the FDA's Center for Drug Evaluation and Research, said in a 745

Tucker Carlson portrayed himself as the victim of a "mob" on Monday night. And he said Fox News has his back."We will never bow to the mob. Ever. No matter what," he said.At the exact same time, on MSNBC, the progressive group Media Matters for America shared even more examples of offensive remarks made by Carlson on a shock jock radio show.The "Bubba the Love Sponge Show" audio clips are from 2006 to 2011. Media Matters is circulating them now as part of a pressure campaign against Fox's advertisers.Without naming the anti-Fox group, Carlson said on Monday night that "they've been working hard to kill this show" ever since it premiered in 2016.When Carlson handed off to Sean Hannity, the two men complained about the scrutiny."There is a mob that wants to destroy only Fox," Hannity said."We're going to fight it," Carlson said.Media Matters said, in effect, that the group is just highlighting the Fox hosts' own words and letting others decide.The first batch of "Bubba" show clips were released on Sunday evening. Carlson was heard making many misogynistic and crude comments. Before long a "fire Tucker" hashtag was trending on Twitter.Fox News declined to comment on the controversy. The network has been battling Media Matters in various ways for many years.Some of Carlson's comments on the radio show date back to a time when he worked at MSNBC. He joined Fox as an analyst in 2009 and he now hosts the 8 p.m. hour, one of Fox's highest-rated time slots.During past controversies about his anti-immigrant point of view, some advertisers 1567

There are places all over the Las Vegas region that are familiar to police. Hot spots that generate a lot of calls. Some might surprise you!KTNV in Las Vegas obtained a year's worth of data from Las Vegas, North Las Vegas and Henderson police departments to track the top locations. Data show police are responding to many of the same places every day, several times a day. As expected, some of the biggest Las Vegas Strip properties with the most traffic generate the most calls to police. The Strip is in Las Vegas Metropolitan Police Department's jurisdiction.New to the top 10 in 2,018, at number 10, is the Wynn Las Vegas with 1,064 calls. That's up from 930 calls in 2,017.Fashion Show mall moved into the top ten also, racking up 1,125 in 2018. That means LVMPD responded on average three times a day, every single day. Click each location for ranking and number of service callsThe 5th location with the most calls is Planet Hollywood at 1,312. In 4th place with 1,567, The Cosmopolitan. The 3rd location is the Bellagio with 1,646 calls. Topped by Caesars Palace in 2nd place at 2,094.And sitting at number one for the second year in a row is MGM Grand with 2,492 calls for service in 2018.While the Wynn and Fashion Show mall are new to the Hot Spots list, the Flamingo hotel and Cromwell casino dropped out of the Top 10 for locations on the Strip. LVMPD tells us the vast majority of these calls are for unspecified trouble, disturbances, suspicious vehicles and cars and theft. 1503

This map from the Ohio Department of Health shows where cases of Hepatitis A have been diagnosed across the state since the beginning of 2018. 154

Treasury Sec. Steve Mnuchin said Friday that the IRS is moving the tax filing deadline from April 15 to July 15.Mnuchin made the announcement on Twitter, saying the move came at the direction of President Donald Trump."All taxpayers and businesses will have this additional time to file and make payments without interest or penalties," Mnuchin said. 362