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President Donald Trump’s physical Dr. Sean Conley confirmed Friday that the president is taking an experimental antibody treatment to help him fight the coronavirus following his diagnosis this morning.Dr. Conley said Friday afternoon that Trump is "fatigued."Trump is taking the Regeneron antibody cocktail, which is currently in a clinical trial. Conley said that Trump has been treated with a single 8 gram dose, which Conley said was infused "without incident."Trump is also said to be taking Vitamin D, zinc, famotidine, melatonin and daily aspirin. The Regeneron trial has only been tried on 275 patients as of this week, but the company said earlier this week that it has showed promising results.Regeneron confirmed that Trump was given the treatment under a "compassionate use request.""In the USA, this type of compassionate use program is also known as an Expanded Access Program (EAP) and is intended for patients with serious or life-threatening conditions, who do not have any viable or available treatment options, and are unable to participate in ongoing clinical trials," Regeneron said in a statement. The plan is to enroll 2,000 patients in early studies of the treatment."After months of incredibly hard work by our talented team, we are extremely gratified to see that Regeneron's antibody cocktail REGN-COV2 rapidly reduced viral load and associated symptoms in infected COVID-19 patients," said George D. Yancopoulos, M.D., Ph.D., President and Chief Scientific Officer of Regeneron. "The greatest treatment benefit was in patients who had not mounted their own effective immune response, suggesting that REGN-COV2 could provide a therapeutic substitute for the naturally-occurring immune response. These patients were less likely to clear the virus on their own, and were at greater risk for prolonged symptoms.The treatment is a combination of two monoclonal and was designed specifically to block infectivity of SARS-CoV-2, the virus that causes COVID-19, the company said.“The two potent, virus-neutralizing antibodies that form REGN-COV2 bind non-competitively to the critical receptor binding domain of the virus's spike protein, which diminishes the ability of mutant viruses to escape treatment and protects against spike variants that have arisen in the human population, as detailed in Science.” Regeneron said in a statement. “Preclinical studies have shown that REGN-COV2 reduced the amount of virus and associated damage in the lungs of non-human primates.”According to Regeneron, the treatment has been tried on hospitalized and non-hospitalized patients and as a preventative for those who have had close contact with coronavirus patients. So far, the drug has been particularly promising for non-hospitalized patients.Regeneron said the treatment reduces the viral load from the coronavirus, and boosts the body’s immune response to the virus. 2890
RAMONA, Calif. (KGTV) - A Ramona couple walking their yellow Labrador puppy say they were attacked by two pit bulls Tuesday night, suffering serious injuries.Michael Dougherty was walking with his wife, Dee, in the Kmart parking lot in the 1800 block of Main Street training their puppy, Rueger. Dougherty said it's easier in the parking lot, as there is more light, compared to their rural neighborhood.As they walked toward the Taco Shop, around 7:15 p.m., Dougherty said from the corner of his eye, he saw two pit bulls charging.RELATED: Dog and owner mauled by pit bull during walk in OceansideThey attacked Rueger and his wife, who went down trying to rescue the dog. Dougherty is recovering from a back injury and walks with a cane. He used it as a weapon."I just started beating the dog, beating the dog, until it [the cane] snapped. This fell down alongside the dog and my wife and she grabbed this and was jamming it into the dog's mouth. When this broke I started punching the dog in the head."Eventually they were able to separate all three dogs. No one escaped uninjured. Dougherty described his wife's wounds, "the top fang went in," gesturing at his left cheek, "and the bottom fang went under her chin like this."RELATED: Pit bull comes to defense of injured owner in apartment, chases away attackers"Both arms are bitten up quite a bit, I couldn't even count them there were so many," he continued, saying her hand bore the worst injury. "Her thumb was bitten three quarters of the way around," saying the skin had been pushed up, away from her hand. "She said she could see the bone, but I don't know about that."Dougherty suffered a bite to his hand as well.As he called 911, he saw the owner and the two pit bulls walking away."It's frustrating to think that he didn't have the courage to stand here and be responsible for what his animals did."RELATED: Family trying to save 'sweetest pit bull on earth' after authorities recommended it be euthanizedDougherty said they don't know how much his wife's emergency room trip will cost. They have a 0 veterinarian bill and said his wife is anxious when he leaves the house.Dougherty hoped by telling their story he would "make people aware and maybe get some information to get this wild animal off the street. He was plain vicious."Animal Control confirmed they have a dog in quarantine, and will have the couple identify Friday whether it's the same dog who attacked them.Dougherty has a GoFundMe set up to help with his wife's expenses. His son said she will be out of work while she recovers. 2572

Reba McEntire's former home in Lebanon, Tennessee has been transformed into an event space, allowing people to host events where one of country music's biggest stars lived for more than a decade.The home, now called The Estate at Cherokee Docks, has seven bedrooms and seven bathrooms. Each bedroom is themed after a Country Music, including Garth Brooks, Johnny Cash, Loretta Lynn, Dolly Parton, Willie Nelson, Patsy Cline, and of course, Reba herself. “We really wanted to be intentional about paying homage to Reba. There are lots of details throughout the house, lots of horses — she loved her horses obviously. Then, we paid tribute to Country Music icons in each of the bedrooms upstairs to really speak to that," Andrea Williams with The Estate at Cherokee Docks, said."This is Country Music history here, and so we wanted to keep that tradition alive.” Throughout the rest of the home, there are touches that Reba herself put in place, such as a movie theater and wine cellar in the basement.Where the property really shines is the event space that is available. Renters have many options inside the home and the rest of property, including the pool, the nearby Cumberland River, the tennis court, and an area under the trees planted throughout the property. “Reba is such a huge icon. To be in her space, to see all of the wonderful things, to see all the personal touches that she added to the property, and now to have it open to the public so that they can experience that too," Williams said. "They can walk in her three-floor closet and work out in her gym with the same equipment that was here when she was here. It’s phenomenal and there’s nothing else like it anywhere else in the city."The space is ideal for company retreats, special events, and weddings, giving people the opportunity to rent the property for the day, overnight, or for an extended period of time. To kick off their first year, The Estate at Cherokee Dock is providing 30 percent off new bookings. You can find more information on their website. 2141
President Donald Trump says he is ready to get back on the campaign trail despite battling COVID-19.Trump said Thursday during an interview with Fox News' Sean Hannity that he is hoping to hold a rally in Florida on Saturday night if his campaign team has enough time to put one together.Trump's push for a rally comes just days after he was hospitalized for coronavirus. The 74-year-old publicly announced his positive test result early Friday morning and was receiving care at Walter Reed hospital before being released Monday evening. Trump has not yet given any specifics on where and what time he'd like the rally to kick off this weekend.Presidential physician Dr. Sean Conley released an update on Trump’s coronavirus prognosis on Thursday, stating that he has “remained stable and devoid of any indications to suggest progression of illness.”Trump was diagnosed with the coronavirus late Thursday night, just hours after traveling to New Jersey for a fundraiser. The following day, Trump was admitted to Walter Reed Medical Center as he was given an experimental antibody treatment, steroids, and other remedies to fight off the coronavirus.By Monday, Conley and Trump’s medical team signed off on releasing him to the White House.Conley said on Thursday he expects Trump to be able to resume public engagements on Saturday. 1340
President Donald Trump's chief economic adviser hosted white nationalist Peter Brimelow at his home last weekend, The Washington Post reported Tuesday.Brimelow, who is known for espousing anti-immigrant ideals and for his role in the white nationalist website VDare, attended Larry Kudlow's birthday party in Connecticut, Kudlow told The Post.Kudlow said he'd known Brimelow "forever" but that "we would never have invited him" had he known about Brimelow's white nationalist ties, according to the paper.Kudlow also told The Post that Brimelow's immigration beliefs are "a side of Peter that I don't know." "I totally, utterly disagree with that point of view and have my whole life. I'm a civil rights Republican," he said, according to The Post.The Post noted that Kudlow's party took place a day after reports surfaced that Trump speechwriter Darren Beattie had left the White House following questions surrounding his attendance of a conference frequented by white nationalists.Beattie previously confirmed to CNN's KFile that he had spoken at the 2016 H.L. Mencken Club Conference, a small annual gathering that started in 2008 and is regularly attended by well-known white nationalists such as Richard Spencer. Brimelow was also listed as a speaker at the conference. Other speakers included regular contributors to VDare.Brimelow told CNN on Tuesday that he has known Kudlow for "nearly 40 years.""I regard him as a personal friend. They knew my first wife, who died, and were most kind to Lydia when I remarried. We agreed to disagree on immigration long ago," Brimelow said.The Post reports that Brimelow does not call himself a white nationalist but had told the Harvard Crimson about the website VDare: "So I don't regard us as a 'white nationalist' site although we certainly publish a few writers I would regard as 'white nationalist' in that they stand up for whites just as Zionists, Black Nationalists do for Jews, Blacks etc."Kudlow was asked by The Washington Post how he would explain the situation to Trump, to which he replied: "Just the way I explained it now, hiding nothing." 2108
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