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BEIJING, Sept. 4 (Xinhua) -- China's railway system has transported some 1.27 billion passengers during the first eight months of this year, up 11.8 percent from a year earlier, the Ministry of Railways said Sunday.The figure has accounted for 67.4 percent of the ministry's full-year target, said the ministry in a statement on its website.The Ministry of Railways has planned to send 1.9 billion passengers in 2011, up 13.1 percent year-on-year.The country's high-speed trains had been operating with improved order and efficiency, said the ministry, which has been required to run high-speed trains at slower speeds, as well as to reorganize bullet train schedules nationwide, for safety reasons.The State Council, or Cabinet, ordered increased safety checks after a fatal train collision that killed 40 people in July raised concerns over the safety of the country's high-speed railways.The ministry cut the number of high-speed trains running between Beijing and Shanghai to 66 pairs from 88 pairs per day, effective as of Aug. 16.Meanwhile, the railways transported more than 2.6 billion metric tons of goods from January to August, up 7.8 percent year-on-year, the ministry said.
LOS ANGELES, July 18 (Xinhua) -- U.S. scientists have proven that oncogenes can change normal cells into stem-like cells, paving the way to a safer and more practical approach to treating diseases like multiple sclerosis and cancer with stem cell therapy.In a collaborative study, researchers from the Keck School of Medicine of the University of Southern California (USC), and the Children's Hospital of Orange County (CHOC) in California and Good Samaritan Hospital Medical Center in New York have successfully converted human skin cells into brain cells by suppressing the expression of p53, a protein encoded by a widely studied oncogene. This suggests that p53 mutation helps determine cell fate -- good or bad -- rather than only the outcome of cancer.Oncogenes are generally thought to be genes that, when mutated, change healthy cells into cancerous tumor cells.Study findings were appearing Monday on the website of the American Association for the Advancement of Science (AAAS)."The reality may be more complicated than people think," said Jiang F. Zhong, Ph.D., assistant professor of pathology at the Keck School. "What is a stem cell gene? What is a cancer gene? It may be the same thing.""When you turn off p53, people think the cell becomes cancerous because we tend to focus on the bad thing," Zhong said. "Actually, the cell becomes more plastic and could do good things, too. Let's say the cell is like a person who loses his job (the restriction of p53). He could become a criminal or he could find another job and have a positive effect on society. What pushes him one way or the other, we don't know because the environment is very complicated."Stem cells can divide and differentiate into different types of cells in the body. In humans, embryonic stem cells differentiate into three families, or germ layers, of cells. The reasons why and how certain stem cells differentiate into particular layers are not clearly understood. However, from those layers, tissues and organs develop. The endoderm, for example, leads to formation of the stomach, colon and lungs, while the mesoderm forms blood, bone and heart tissue. In its study, Zhong's team examined human skin cells, which are related to brain and neural cells from the ectoderm.When p53 was suppressed, the skin cells developed into cells that looked exactly like human embryonic stem cells. But, unlike other man-made stem cells that are "pluripotent" and can become any other cells in the body, these cells differentiated only into cells from the same germ layer, ectoderm."IPSCs (induced pluripotent stem cells) can turn into anything, so they are hard to control," Zhong said. "Our cells are staying within the ectoderm lineage."Zhong said he expects that suppressing other oncogenes in other families of cells would have the same effect, which could have critical significance for stem cell therapy. Future research should focus on determining which genes to manipulate, Zhong said.The study is slated to appear in the Proceedings of the National Academy of Sciences later this month, according to AAAS.

LOS ANGELES, June 5 (Xinhua) -- A latest study has found no evidence that screening for ovarian cancer may reduce the risk of dying from the disease, it was reported on Sunday.Screening, however, does increase the likelihood of unnecessary invasive procedures, according to researchers at the University of Utah.The researchers presented their findings at an on-going meeting of the American Society of Clinical Oncology in Chicago, The Los Angeles Times said.Researchers studied 78,216 women, ages 55 to 74, who participated in the National Cancer Institute's Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial. Half of the women received the usual care from their OB-gyns, and half received a CA 125 screening every year for six years and an ultrasound every year for four years. They were then followed for a maximum of 12 years.The researchers observed 212 ovarian cancers in the screened group and 176 in the normal care group. There were 118 ovarian cancer deaths in the screened group and 100 in the normal care group. The differences were not statistically significant. Overall, there were 2,924 deaths from all causes in the screened group and 2,914 in the normal care group.But the researchers also observed that 3,285 women had false- positive diagnoses from the screening. Among those, 1,080 underwent surgery that included an oophorectomy (surgical removal of one or both ovaries). Fifteen percent of those who had surgery developed major complications as a result. Overall, 1,771 women in the screened group (7.7 percent) had an oophorectomy, compared with 1,304 in the normal care group (5.8 percent)."We conclude that annual screening for ovarian cancer ... does not reduce disease-specific mortality in women at average risk for ovarian cancer but does increase invasive medical procedures and associated harms," the researchers said in the study.New data presented at the meeting also showed that the widely used cancer drug Avastin can improve treatment of ovarian cancer, The Times said.About 21,880 American women are diagnosed with ovarian cancer each year and about 13,850 die from it, according to the American Cancer Society. Because it produces few symptoms, the disease is typically not diagnosed until it has become advanced and spread throughout the body. As a result, five-year survival is only about 30 percent, and the disease is one of the five most deadly cancers among women. Being able to detect the cancer at an earlier stage when it might be more curable could thus, theoretically, improve the survival rate.The tests most commonly used to detect ovarian cancer include a transvaginal ultrasound to look for tumor masses and a blood test that screens for increased levels of a tumor marker called CA 125.
CHENGDU, Sept. 20 (Xinhua) -- A United Nations official said Tuesday that she hopes China will take every opportunity to reinforce, support and lead the UN's agenda and "infuse it with strength and wisdom.""The more China gives, the better the UN can become," said Renata Lok-Dessallien, UN Resident Coordinator and United Nations Development Program (UNDP) Resident Representative in China, at the Seminar in Memory of the 40th Anniversary of the Resumption of Lawful Rights of China in the United Nations.The three-day seminar from Sept. 19 to 21 is being held in the city of Chengdu in southwest China's Sichuan Province. About 100 UN and Chinese officials are gathering to discuss China's role in the UN, as well as the UN's role in global diplomacy.Lok-Dessallien said that the General Assembly Resolution of Oct. 25, 1971 was an "important milestone in China's international relations and in the history of the United Nations.""It restored the rights of the People's Republic of China in the United Nations and marked China's entry to the world stage," she said.Steven Sabey, a senior policy advisor from the UNDP's China office, said that China plays an important role in facilitating cooperation about the member states of the United Nations."China needs the United Nations, and the United Nations also needs China," said Wu Hailong, China's assistant minister of foreign affairs."We must recognize that as the largest developing country in the world, China needs to manage its domestic affairs first, as this can have a positive effect on humanity as a whole," Wu said.As China's role in the world continues to grow and evolve, the UN's role in China will also grow, according to Lok-Dessallien."As China's development trajectory continues to evolve, we are entering significantly new territory in the UN-China relationship," she said.Sabey said that he hopes China will strengthen its cooperation with the United Nations in order to further improve intercultural communication and allow China to contribute more to other developing countries."The United Nations is committed to continuing to deepen and strengthen our partnership as we tackle the many global challenges ahead," said Lok-Dessallien.
BEIJING, June 21 (Xinhua) -- China will launch a new icebreaker for use during an upcoming 2013 polar expedition, a senior oceanic official said on Tuesday.Both the new icebreaker and Xuelong ("Snow Dragon"), an icebreaker that operated in Antarctica, will form an Arctic-Antarctic maritime research team."China will have at least two icebreakers concurrently operating at both the north and south poles," Chen Lianzeng, deputy director of the State Oceanic Administration, told a national conference on polar research, which has been the first since 1984 when the country started expeditions in polar regions.The new icebreaker will boast facilities that will allow it to research the oceanic environment, integrate data for real-time oceanic monitoring, deploy and retrieve detectors and conduct aerial studies using helicopters, Chen said.The two icebreakers will conduct expeditions in polar regions for more than 200 days annually, he said.Fixed-wing aircraft will also be added to the expedition team before 2015, allowing researchers to be transported between China's Zhongshan and Kunlun research stations and Antarctica's Grove Mountains.The Kunlun station went into operation in early 2009 as the first Chinese research station on Antarctica's inland. The Zhongshan station, established in 1989, now serves as a supply base for the Kunlun station.A written comment by Vice Premier Li Keqiang sent to the conference said the polar research, a magnificent feat of the mankind, has great significance for China's oceanic work and sustainable development."Over the past two decades, China's polar research made great achievements and became influential globally," Li said.Li encouraged Chinese scientists to actively participate in international exchanges and cooperation, safeguard national interests and contribute to the peaceful use of polar regions.Since the early 1980s, China has sent 27 Antarctic expedition teams and completed four research missions to the Arctic Ocean.Besides the Xuelong icebreaker, China has built three Antarctic stations -- Changcheng (Great Wall), Zhongshan and Kunlun -- and one Arctic station -- Huanghe (Yellow River) Station.
来源:资阳报