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发布时间: 2025-05-24 05:46:53北京青年报社官方账号
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SAN DIEGO (KGTV) -- We’ve known for a while that COVID-19 hits people over 65 especially hard, but a study published Wednesday from researchers in San Diego offers new insight into why that happens.The numbers are staggering: if you’re 65 or older, your risk of winding up in the hospital from COVID-19 is five to 11 times higher than someone under 30. Your risk of death is at least 90 times higher, according to data from the Centers for Disease Control and Prevention.Researchers at the La Jolla Institute for Immunology say the reason why older people fare so much worse appears to be from a lack of T-cells, a type of white blood cell that can decline with age.“Some viruses get controlled by one part of the immune system. Some viruses get controlled by another. In this case it seems that T-cells really do a lot of the work,” said Dr. Shane Crotty, one of the authors of the study published Wednesday in the journal Cell.Dr. Crotty and his colleagues looked at 50 people infected with the virus, and they measured the three elements of the adaptive immune system in detail: antibodies, helper T-cells and killer T-cells.Then they compared the measurements to how people fared against the virus. Some patients in the study group had severe cases, others had mild infections.The researchers found that people with all three branches of the adaptive immune system tended to fully recover. People with severe cases of the virus often lacked one or more of the immune branches, and it was particularly evident in older people.“Our data indicated that of the older individuals, it was particularly the ones that had fewer T-cells to start that look like they really struggled to control this virus,” Dr. Crotty said.As we age, we have fewer T-cells to send after invading pathogens. “That collection of T-cells gets smaller. So it’s harder to recognize a new virus,” Crotty said.Among the 748 deaths in San Diego County reported as of Wednesday, 87% were people aged 60 and older.The findings from LJI may have implications in the search for a vaccine against COVID-19. The data suggests that vaccine-makers may want to target a drug that elicits all three branches of the immune response, Dr. Crotty said. Some vaccine approaches, such as inactivated virus vaccines, only elicit two of three branches, not killer T-cells. However, Crotty said it was too soon to rule any candidates. Two strong branches produced by a vaccine could potentially cover for the lack of a third, he said.Crotty said the findings could help vaccine-makers interpret results from the clinical trials and find the right dosing.“Is a given vaccine a good vaccine, and you just need a booster immunization?” he said. “Does it work well in one population but it doesn’t help in the elderly because it doesn’t generate a T-cell response, for example? Those are the scenarios when this type of knowledge will come into play.” 2906

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SAN DIEGO (KGTV) -  There are disturbing allegations that the foster system in San Diego County failed children it was supposed to protect.Critics question whether the rules of confidentiality designed to protect children are doing more to shield social services from scrutiny."My children are going to have to live a lifetime trying to get over and deal with this trauma,” said Melanie. 10News is not sharing Melanie’s last name to protect her adopted children. She is an adoptive mother and foster parent."I became a foster parent because I did want to make a difference in children's lives that didn't have families,” she said.Melanie said she became a foster parent about a decade ago. She wanted to give children in need a safe, loving home.However, Melanie says a potential adoptive child placed with her in 2015 ripped the joy right out of her home.The foster child “ended up sexually assaulting all three of Melanie's adopted sons,” said Melanie’s attorney Jomo Stewart.Stewart said they filed a lawsuit against the County of San Diego, several county employees, and a national foundation that focuses on foster care alleging they all were negligent in placing the child with Melanie’s family.The lawsuit said the county assured Melanie the potential foster child had no history of sexual misconduct, mental illness or any history of wrongdoing.The suit claims that social services concealed the child's past issues and put her sons in unreasonable harm.According to Melanie’s lawyer, Melanie "asked social services whether or not these children had any type of mental health issues, had any previous history of being sexually abused or any previous history of sexually acting out and all answers to those questions were no.”Court documents claim about a month after taking the child into her home the child began to act out, including incidents such as smearing feces on the wall and downloading and watching pornography. Court documents stated that the child “took one of the boys’ cell phones and again downloaded homosexual child pornography.”Then things escalated.The suit claims there were several incidents of sexual violence against the other children in the home over the next year.Melanie says her son was traumatized and is still in counseling trying to deal with it.After each incident, Melanie said she reached out to county social services employees seeking help."Sometimes there was no response at all,” Melanie said. “Sometimes they said that they were going to place a report, I'd follow up on the report, I wouldn’t get any information.”According to a representative with the County of San Diego’s Child Welfare Services division, as of July 2017, there were more than 3,692 open child welfare cases and more than 2,365 kids placed in foster care, which is less than the year before There are 712 caseworkers but not everyone directly handles a foster child's case.Although there is no mandate for how many cases a social worker can carry the county says caseloads are monitored and assigned on a monthly basis. Case count per caseworker often fluctuates based on changing circumstances of every case.A spokesperson for the county denied all interview requests for this story. However, attorneys for the county did respond to the lawsuit in a court filing asking that it be dismissed.The response noted the records in the county's possession at the time the foster child was placed in the home didn't include any information that would have alerted them that the child may pose a risk of harm.They also claim there are no factual allegations to support that they failed to take appropriate action. After each incident, they did take action by filing a report and commencing an investigation, according to the county's court filing.Team 10 investigator Adam Racusin asked San Diego attorney Shawn McMillan if it’s surprising to see allegations like the ones in Melanie’s complaint against San Diego County and the foster system. “No, no the foster system not just in San Diego County, but statewide is completely and totally broken,” McMillan said. McMillan is one of only a handful of attorneys in California who specializes in child welfare cases. He said one of the most significant problems in the system is that everything is done in secret."I've dealt with San Diego County for a long time,” he said. “These specific attorneys defending this case, I have cases with them right now, and it's typical to see what they're doing here, it's blame assignment, denial -- a refusal to be held accountable.”According to Melanie's lawsuit, the district attorney's office filed felony delinquency charges against the foster child for sexual abuse, after the placement with Melanie.Melanie said had she known the child's history there's no way the placement would have taken place. 4928

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SAN DIEGO (KGTV) -- With the demolition of SDCCU Stadium underway, much of the talk has been about how to buy the seats. But there's a lot more that could go at a fraction of the price.San Diego State University will auction off hundreds of mementos from the stadium in December, including a variety of signage -- from seats to parking lot -- and heavy duty equipment, such as electric carts and automotive lifts. Starting bids range from to . Heritage Global Partners will be handling the auction, which runs online from Dec. 14 to Dec. 16. Pre-registration is available now.“Unfortunately we can't save the stadium, that's bigger than us, but we can save a piece of it for you," said Tim Shaeffer, Director of Business Development at Heritage Global Partners. Fans can buy 15-inch-by-15-inch signs that directed fans to their sections. Of note, a Section 55 stadium sign designed to honor Chargers great Junior Seau, starting bid .Buyers pay 7.75 percent sales tax as well as an 18 percent fee on purchases. Items can be picked up the week after the auction, so buyers can have them before the Holidays. SDSU has also announced that seats from SDCCU Stadium will go on sale to the general public at 9 a.m Dec. 1. Buyers must purchase two because they share arm wrests and do not stand on their own. A general public price has still not been announced, but similar sales have been in the 0 to 0 range for a pair, the university says. The seats cost 9 in a presale to Aztec Club members.Proceeds from seat sales will be re-invested into the project to build a 35,000-seat stadium for the Aztecs. Construction is underway in the SDCCU Stadium parking lot, with scheduled opening in 2022. 1714

  

SAN DIEGO (KGTV) — With the pandemic prompting San Diegans to wear facial coverings, and practice physical distancing and stringent hand hygiene, flu season's start has been slowed.According to the county's Influenza Watch report published Oct. 21, San Diego County has reported 10 flu cases to date this season, compared to 320 cases at this time last year. Last year's season totaled 20,711 flu cases.The county says no influenza-related deaths have been reported so far this season. The CDC says the flu season in the U.S. typically occurs in the fall and winter, with the season peaking in December and February.County health officials say health precautions due to the coronavirus and an increase in the rate of residents receiving flu vaccinations have kept flu numbers low so far."Influenza activity has been very low so far this season in San Diego County. This may in part be due to the social distancing, hand washing, and mask wearing interventions instituted to reduce the transmission of SARS-CoV2, the virus that causes COVID-19. Seasonal influenza vaccinations are being recorded in the San Diego Immunization Registry at a higher rate than at this same point in any previous season, with 637,696 San Diegans immunized through week 42," the county's report said.Week 42 covers case totals up to the week ending Oct. 17.According to the county, 70% of this year's flu cases cover Influenza A, while 30% include Influenza B. 1445

  

SAN DIEGO (KGTV)- A Solana Beach man's trip to Bali takes an unexpected turn after a motorcycle accident. While he's thousands of miles away, the pandemic has made things even more complicated.28-year-old Anthony Galvan- Schaible packed his bags for Bali in February with the intent to stay until April. In March, the pandemic hit, forcing him to stay in Paradise a little longer."It was one of those things to sit it out and wait was the better idea," says Galvan- Schaible.He says one night he hopped on his motorcycle, and that's when things took an unexpected turn."The bike went to the street. I went to the left and ended up in a little ditch head first."He was rushed to the hospital after hitting his head on a concrete pillar. The impact compressed his spine. Within hours he was taken to emergency surgery. Galvan- Schaible now has multiple screws and plates along his back."It's terrifying… when they're across the planet and get hurt," says Mom, Jamie Schaible. "All you can think of is how can they get the care that they would get here."Because of travel restrictions, mom says it was stressful not knowing how she would get to her son."We reached out to the Indonesian embassy and just pleaded from a mother's heart and leaned on their compassion," says Schaible. "They bent over backwards to get me my visas."This allowed her to get to her son's bedside.Galvan-Schaible says he is starting to regain feeling in his hand. He will stay in the hospital a few more weeks before taking an air ambulance flight back to the U.S.A GoFund Me page has been set up to help with medical expenses and to get him back to the U.S. 1639

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