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KANSAS CITY — Maureen Boesen has always known cancer risk was high in her family."We're able to really track our history of breast cancer back to the late 1800s and early 1900s," Boesen said. "My grandmother actually passed away from ovarian cancer when she was 44. She had five sisters and none of them lived to the age of 50. Then, my mother was diagnosed with breast cancer when she was 32. We knew there was something going on and that it was a very young age."When Boesen and her two sisters were ages 3, 5 and 7, their mom was already receiving chemotherapy for stage 2 breast cancer. Because of the extensive family history, the girls were part of a study at a university in another part of the Midwest. Their mom was hoping to help the world better understand what was killing so many women. She was hoping to better her daughters' chances for survival."We were all tested in the same exact room," said Boesen's sister, Bridget Stillwell. "I can even remember what the room looked like." Because the girls were so young, and the health threat still likely years away, they wouldn't receive their DNA test results until they turned 18."We knew we were part of a study," Boesen said. "We knew our results were waiting for us, but we didn't know what they were."When asked if she found that wait frustrating, she said emphatically it was not."Quite the opposite. We felt empowered," she said.She didn't get the results right away. The sisters knew there was nothing they could likely do at age 18 even if their test results showed they'd inherited the BRCA gene mutation. The sisters all waited until they were around age 21. One sister was positive. One sister was negative. Boesen remembers meeting with the researcher to learn her results."We sat down and we had a conversation about what BRCA was and what it meant for my family," Boesen said. "It was a lengthy conversation, which made me very uncomfortable because why would a conversation that wasn't going to change my life last that long?"Eventually, the researcher told her she had inherited the gene mutation."It was just devastating because I knew what breast cancer and ovarian cancer can do to a family. You know, my first question out of my mouth was, 'Is there any chance this could be wrong?' The researcher said 'No.' "Boesen walked out of that meeting determined. She was going to make decisions to save her own life. She was going to have a bilateral prophylactic mastectomy. She would schedule a surgery to remove both breasts to prevent breast cancer."This was me doing what I was supposed to do and this was me being empowered and me being proactive and not waiting until I have a cancer diagnosis," Boesen said.She didn't want to feel like a ticking time bomb. She wanted to live.Boesen had the surgery to remove both breasts when she was just 23 years old. She went on to get married and have three children."I didn't get to breastfeed them. It was sad. I'm not brokenhearted or devastated about it, but it is sad to think I couldn't provide for my children like that," she said.At the time, she still believed she'd made the right decision because she was healthy.Once done having children, she knew there was another step that most people with the dangerous BRCA gene mutation have to consider."I knew that when I was done having children, I needed to have a complete hysterectomy," Boesen said.The BRCA gene mutation not only dramatically increases a woman's chance of developing breast cancer at a young age, it also significantly increases a woman's chance of ovarian cancer."The right thing to do and what the doctors say to do is have a complete hysterectomy by the age of 35 and I was in my early 30s," Boesen said.In 2018, she went to a hospital in Kansas City, Missouri, to start the process of preparing for her hysterectomy. Both her health care provider and her insurance company wanted a new DNA test. Everyone knew what the results would be, but they went through the motions to get the required confirmation she was positive for the deadly gene mutation which was so rampant in her family.The test results were supposed to be back in a few weeks, but it had been four and Boesen was starting to worry. Then, she got the call from the doctor."I was at work. And the first thing she said was, 'We need to talk', and my heart just sank," Boesen said. "She said, 'You're negative,' and I just started bawling."She was overwhelmed, confused and full of emotions."I was angry. I was regretful. I was happy. I was sad. I so desperately wanted to feel relief, 'Oh, thank God, this is the best day of my life,' but it wasn't," Boesen said. "It was just devastating."Boesen got another test to confirm the second test results. It also came back negative.She did not get the hysterectomy. There was no need now. There was no longer a threat that cancer was waiting to explode in her body. She now knew she had not inherited the BRCA gene mutation that had killed so many of her relatives.Dr. Jennifer Klemp of the University of Kansas Cancer Center has worked in the field of cancer genetics, specifically breast and female cancers, since 1997. She is the director of Cancer Survivorship and a cancer risk counselor. While she was not involved in Boesen's original research, she says she's not surprised."Twenty years ago, when we sent our first tests and BRCA 1 and 2 were the two genes we tested for, about 30-40 percent of the time we would get something called a 'variant of uncertain significance,' " Klemp said. "Basically, that meant we found a mutation or an error in the DNA, but we didn't know if that was associated with an increased risk of cancer. Today, using a reputable lab, that should be less than 1-2 percent."Klemp says things are changing rapidly in the field of genetic testing. If someone had a DNA test more than five years ago, they should consider having an updated test. She also says the at-home tests are good for finding out details about your ancestry, but they shouldn't be used to make major decisions about your health. For that, you'd want a health professional to order a commercial test through a certified, reputable lab. With more and more companies offering testing, and more medical professionals and patients interested in genetic testing for so many reasons, she says demand right now is outpacing supply."If you have 10 different labs doing testing, and you have every primary care, OB-GYN, oncology clinic, surgical clinic and any number of patients eligible for testing, it's a little bit of the wild west," Klemp said, adding there's no central repository for this patient and test information.As for Boesen, the university where the original research was done and the false positive originated offered to re-test her DNA. She is currently waiting on the results from what is now her fourth genetic test. She hopes it comes back negative, too, which is what the experts all expect. She believes, then, finally, she'll be able to move forward with her life. Boesen and her two sisters are writing a book about their experiences. Each of her sisters has a story to tell, too. Their book will be titled, " 7146

It was a long year for the Virginia Cavaliers after becoming the first No. 1 seed ever to lose in the first round of the NCAA Tournament. The 2018 loss proved to Virginia that you cannot take anything for granted. Fast forward to 2019, Virginia was back in the NCAA Tournament again as a No. 1 seed. This time, Virginia took care of business. Virginia won in its first ever National Championship appearance, defeating No. 3 seed Texas Tech of the Big 12 Conference, winning by a 85-77 margin in overtime.Virginia was powered by an 11-0 run in overtime. Virginia hit all 12 of its free throws in overtime. The loss to UMBC in 2018 was on everyone's mind throughout this March Madness."Heard about it a lot, and we knew that," Virginia coach Tony Bennett said. "I feel like I repeat myself too much. In a way, it's a painful gift. It did draw us nearer to each other as a team. I think it helped us as coaches. I think it helped the players on the court and helped us in the other areas that rely on things that were significant."I think that karmic payback, I don't know. I knew it was going to be a significant year in all of our lives. I knew that going into this year because of what was going to be coming at us because of that from a basketball standpoint. So I just knew we needed each other."Virginia nearly repeated history, as it trailed by 14 in the first round of its tournament opener three weeks ago. Then Virginia nearly got knocked out of the tournament in the Elite 8 against Purdue on March 30, but a late comeback gave Virginia an overtime win. And on Saturday, Virginia converted on a controversial call to defeat Auburn by one to advance to Monday's title game. This Virginia team continued to persevere.On Monday, Virginia had a 32-29 lead at halftime, and would lead by as much as nine in the second half. Texas Tech went on a 7-0 run to tie the game at 59-all with 3:58 left. After trading free throws, Virginia led 65-61. But a huge by Texas Tech helped spark a 7-0 run. But with the game tied at 68, Texas Tech's Jarrett Culver had his shot blocked at the end of regulation, forcing overtime. 2129

Jed Allan, star of "Beverly Hills, 90210" and several soap operas, died at the age of 84, according to the actor's fan page on Facebook."So sorry to post the very sad news of my fathers passing tonight," his son, Rick Brown, 237

Italian law now requires vehicles to have a safety device that alerts drivers if a child has been left behind in the rear seat or a car seat.The law went into effect Thursday and is designed to prevent hot car deaths. Some devices will send visual and audible alerts when someone gets out of the car, according to the Ministry of Infrastructure and Transport. Other devices will send signals to the driver's smartphone that it is out of range from the sensor on the child's car seat.Fines between 88 and 333 Euros can be imposed and drivers can lose points on their licenses. A second infraction would mean the driver's license would be suspended for at least 15 days.The law applies to parents of children under 4 years of age.The ministry says the devices are available online and in stores specializing in children's items. Parents at some point will be able to submit a receipt to the government to recoup incentive money. The government has not yet worked out the reimbursement paperwork, the ministry said.The law was proposed in 2018 after several hot car deaths.How the US is dealing with hot car deathsAccording to 1136

LAKELAND, Fla. — Records show the Florida Department of Highway Safety and Motor Vehicles (FHSMV) made million in 2017 by 138