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SAN DIEGO (KGTV) — Independent reviews by the FDA show the COVID-19 vaccines by Pfizer and Moderna have similar levels of safety and efficacy, although there are early indications of potential differences.Both vaccines rely on the same basic approach: jumpstarting the immune system with messenger RNA. The FDA confirmed their overall efficacy is essentially identical; 95 percent for Pfizer and 94.1 percent for Moderna.However, signals in the data suggest Moderna’s vaccine may better protect against severe cases of COVID-19, while Pfizer’s vaccine may work better in adults over 65. But experts warned those differences may just be statistical illusions.In Moderna’s study of 30,000 volunteers, 30 people got severe cases of COVID-19. All 30 of those cases were in the placebo group, suggesting the vaccine offers powerful protection against the most serious symptoms.In Pfizer’s trial of 44,000 volunteers, one vaccinated person got a severe case compared to 10 people in the placebo group.“We still need more data,” said Dr. Abisola Olulade of Sharp Rees-Stealy. “It's not a reason to recommend one versus the other.”In adults over 65, the efficacy of Moderna’s vaccine dipped slightly to 86.4 percent. Pfizer’s vaccine was 92.9 percent effective in people aged 65 to 74 and 100 percent effective in individuals 75 and up.“When I think people in the community look at that number, they might say, ‘Oh, that Moderna vaccine probably isn't as good for the older population compared to the Pfizer vaccine.’ But as a clinician looking at numbers, they're both amazing,” said UC San Francisco infectious disease expert Dr. Peter Chin-Hong.FDA scientists found both vaccines are safe but short-term side effects are common, especially with Moderna’s drug. Both vaccines are administered in two doses. The table below lists the percentage of vaccinated volunteers who reported a side effect after either dose, although side effects were most common after the second injection.Side effect Moderna PfizerFatigue 68.5% 62.9%Headache 63.0% 55.1%Muscle pain59.6%38.3%Joint pain44.8%23.6%Chills43.4%31.9%Fever14.8%14.2%Typically the symptoms went away in one day.“Just because a vaccine has side effects doesn’t mean it’s not safe,” said Dr. Olulade. “We know that side effects happen actually because your immune system is working and waking up. It's actually a positive thing.”The slight difference in side effects could be because of differences in the way researchers polled volunteers, or it could be something with the architecture of the vaccines, experts said.The companies use different tiny bubbles of fat to enclose the messenger RNA. Moderna’s bubble is a little stronger and more stable so it doesn’t need to be stored at sub-arctic temperatures.“It could be that [Moderna’s] elicits a little more inflammation than the other,” Dr. Chin-Hong said.Having slightly more side effects could be a sign that Moderna’s vaccine prompts a stronger immune response that might lead to longer-lasting immunity, but the durability of either vaccine remains one of the most pressing unanswered questions.The biggest difference may be where the vaccines are deployed. Since Pfizer's vaccine needs to be stored at such cold temperatures, experts said Moderna's vaccine may be prioritized for rural hospitals and community health centers that lack ultra-cold storage units. 3370

SAN DIEGO (KGTV) — In Pacific Beach, it's common to see scooters in the flow of traffic.At night, it's the same story. Firefighters plagued with trauma patients from scooter crashes. Crews say they often see people using them to bar hop.A study released Thursday reveals data supporting exactly that. The study focuses on 103 patients and after tests it shows that half of them were drunk. Even more surprising, 52% were high on drugs.The study pulled data from UCSD Medical Center, Scripps Mercy Medical Center, and a hospital in Austin, Texas."We were concerned this would become the next big public health issue," says UC San Diego Health Dr. Leslie Kobayashi.The study looked at patients between September 1, 2017 to October 31, 2018."Spinal fractures and spinal chord injuries," Kobayashi says, recalling injuries. "I myself saw one patient who was not able to be salvaged because of a severe overwhelming devastating head injury."Kobayashi seeing the skyrocketing trend from the emergency room.New rules started in June to combat these stats, like limiting the speed of scooters in places like the boardwalk and forcing riders to park scooters in corrals.Firefighters in Pacific Beach say they're seeing less injuries in the last month.Kobayashi hopes it's just the beginning."Reducing the speeds, limiting the times of day it can be used, and whether or not protective gear, most importantly helmets are going to have an impact on injury prevention," Kobayashi added.The conclusion of the study reads, "eScooter-related trauma has significantly increased over time. Alcohol and illicit substance use among these patients was common, and helmet use was extremely rare. Significant injuries including intracranial hemorrhage and fractures requiring operative intervention were present in over half (51%) of patients. Interventions aimed at increasing helmet use and discouraging eScooter operation while intoxicated are necessary to reduce the burden of eScooter-related trauma."10News reached out to Bird and Lime for a response.Lime said they are "piloting a new function in the app - “Don’t drink and ride” - whereby those trying to rent a Lime after 10pm now have to confirm they are not attempting to rider under the influence."Both companies said safety is their priority.Bird sent us this statement, in part, "The rules of the road, apply to everyone — whether behind the wheel, walking, cycling or on a scooter. We go to great lengths to educate and inform riders about the dangers of distracted riding, including riding under the influence, as well as educating them on how to identify drivers who might be operating cars under the influence." They provide in-app messages and emails reminding riders not to drink and ride.The study acknowledges their information may be skewed, "Using patients only from Level 1 trauma centers may skew our data by excluding many of the less severely injured patients who were triaged to lower level trauma centers and non-trauma centers." 2995

SAN DIEGO (KGTV) — Low-lying parts of San Diego are dealing with the possibility of more coastal flooding Saturday and Sunday morning because of "King Tides." The high tide event is expected to occur the mornings of December 22 and 23, according to tidal charts. King tides occur when there is an alignment of the gravitational pull of the sun and the moon. RELATED: Sandbags available in San Diego CountySome parts of Imperial Beach already experienced tidal flooding Friday morning as several homeowners reported water entered their homes. Wow! Really high tide here in Imperial beach. Water soaking the area. @10News pic.twitter.com/F3P6dNr7HS— Mimi Elkalla (@10NewsMimi) December 21, 2018 700

SAN DIEGO (KGTV) — In response to the coronavirus pandemic, Qualcomm is requiring employees able to work from home to do so.In an email sent to employees, the company moved to "a global required work from home policy for employees who are able to perform their job remotely" effective immediately through March 27. A Qualcomm spokesperson confirmed the email to 10News.The company email says employees in China should continue to follow local guidelines that they've received separately."Certain employees will be identified as 'onsite critical,' which means that your work is both critical to the continuity of business operations and requires onsite presence to perform your work duties," the company's email read.Qualcomm said it is taking the action as a "proactive, preventative measure to protect our employees and help reduce the spread of the virus."The San Diego Regional Economic Development Corporation estimated in early 2018 that the company has a .9 billion impact on the San Diego economy. Founded in 1985, Qualcomm is one of San Diego's largest employers, employing more than 33,000 people worldwide. 1126

SAN DIEGO (KGTV) -- If you own boat -- or even a kayak or a jet ski -- that's just sitting in a dock or on a trailer, you may be sitting on some extra income."Business has been ..." Karina Sanchez searches for the right words. "We can't even believe how great business has been, we're so so thankful for it."Sanchez and her husband are owners of Waterhorse Charters in Mission Bay. Opening just last year, they offer scuba diving tours, party cruises, fishing and whale watching excursions.When the pandemic hit, they were forced to temporarily shutdown by state mandate. But once given the green light to reopen, Sanchez says business has been booming, with people want to get out and do it safely."I feel like people get a little more comfortable going out in the water," says Sanchez, "Something that's outdoors; than having, for instance, a house party or just going to bars or something like that."Sanchez connects with many of her customers through the site GetMyBoat.Com, which is kind of like Airbnb for boats."There's some data that suggests the average boat is only used 8 to 10% of the year," says Val Streif, who represents GetMyBoat.com from their headquarters in Minneapolis. "And the other time it's just sitting in a dock or marina."Streif says GetMyBoat has listings from private boat owners and charter services in 184 countries around the world, offering everything from kayaks and jet skis to pontoon boats and yachts."This is a way for people to earn some supplemental income," says Strief, "When they're not using the boat for themselves for personal purposes."There are increased regulations during the pandemic -- stepped up cleaning, fewer passengers for social distancing and other steps depending on the boat or excursion offered."We require everybody to wear a mask while they're on board," says Sanchez, "When they rent a regulator -- which is the piece you put in your mouth when you're diving -- every time people rent one from us we make them buy the mouthpiece."Sanchez says the changes aren't hurting business, as they've been sold out. And they're not the only ones, which is why GetMyBoat.com looking for more boat owners to sign up and perhaps help themselves "stay afloat" during these tough times, by renting out their boat.Sanchez says the demand is definitely there."Everybody is just grateful they can go out on the water. So, it's been great." 2394

来源：资阳报