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WASHINGTON, Dec. 7 (Xinhua) -- The use of two drugs never tried in combination before in ovarian cancer resulted in a 70 percent destruction of cancer cells already resistant to commonly used chemotherapy agents, say researchers at Mayo Clinic in Florida.Their report, published on-line Wednesday in Gynecologic Oncology, suggests that this combination, ixabepilone and sunitinib, might offer a much needed treatment option for women with advanced ovarian cancer.Neither drug is approved for use in ovarian cancer. Ixabepilone is a chemotherapy drug that, like other taxane drugs, targets the microtubules and stops dividing cells from forming a spindle. It has been approved for use in metastatic breast cancer. Sunitinib, approved for use in kidney cancer, belongs to a class of tyrosine kinase inhibitors that stops growth signals from reaching inside cancer cells.When caught at late stages, ovarian cancer is often fatal because it progressively stops responding to the chemotherapy drugs used to treat it."Women die from ovarian cancer because their tumors become resistant to chemotherapy, so a drug that might be able to reduce that resistance -- which may be what this combination of agents is doing -- would be a boon to treatment of this difficult cancer," says study coauthor Gerardo Colon-Otero.The finding also highlights the importance of the role of a molecule, RhoB, that the researchers say is activated by the drug duo. It might be a potential biomarker that may help identify patients who might benefit from such combination therapy, the researchers say.

BEIJING, Jan. 22 (Xinhua) -- China restored 23,000 hectares of wetlands in 2011, according to the latest figures from the State Forestry Administration (SFA).An SFA spokesman said China reinforced wetland protection in 2011 by increasing subsidies in protecting wetlands. In the year the country carried out 42 wetland protection projects, increased 330,000 hectares of protected wetland areas, added four wetlands of international importance and 68 national wetland parks.The spokesman said in 2012 the country will further step up wetland protection and restoration, finish the second national wetland resources investigation and carry out pilot projects in assessing healthy conditions of the wetland ecological system.So far China has built more than 550 wetland natural reserves, 37 wetlands of international importance, which were listed in the Ramsar international wetland convention, and 100 national wetland parks. About half of the country's natural wetlands have been brought under effective protection, the SFA said.

CANBERRA, Oct. 15 (Xinhua) -- Prisoners and health experts on Saturday told national broadcasting network ABC News that they are concerned of a looming HIV epidemic in Australia's prisons.The warning came following a test report undertaken in August showed that 40 percent of inmates at a correctional center in Canberra of Australia tested positive to Hepatitis C.According to the head of the Alcohol and Drug Service based at St Vincent's Hospital in Sydney, Alex Wodak, roughly 25 percent of Australia's prison population are injecting drugs, and he is concerned about the risk of an HIV explosion in Australia originating in prisons."Were Australia to have an epidemic of HIV beginning among people who inject drugs, it is almost certain that it would begin in one of our prisons. So we are very exposed to this risk," he told ABC News on Saturday.The Australia Capital Territory state government has proposed a trial prison needle exchange program in Canberra's correctional center, and Paul Cubitt, who currently works at the Alexander Maconochie Center in Canberra, said he has never seen so many syringes in a jail."Under a controlled regime it will actually take those needles that currently exist within a correctional center out of the environment, and prisoners will be more willing to use a clean item under a level of anonymity which then protects them and protects staff," he said.Meanwhile, The Community and Public Sector Union 's national secretary, Nadine Flood, agrees action must be taken to curb prisoner drug use.Dr Wodak noted that prison needle exchange programs have been operating overseas for over a decade with ten countries provide inmates with clean needles, and said it is shameful Australian prisons are lagging behind.

BEIJING, Oct. 21 (Xinhua) -- China's State Councilon Thursday called ordered improved, innovative administration in environmental protection, according to a statement.In a statement published on the central government's website, the State Council listed a series of guidelines on environment-related issues, saying that it will step efforts to address prominent environmental problems that affect people's lives and sustainable development.The statement ordered strictly implementing environmental impact assessment, vigoroulsy developing environmental protection industry, and ensuring nuclear and radioactive safety.It called for implementing economic policies beneficial to environmental protection.The statement also ordered local governments at all levels to attach more importance to environmental protection, noting ecological conditions should be considered in evaluating the performance of local leaders.

SANTO DOMINGO, Sept. 30 (Xinhua) -- Haitian health authorities on Friday said the number of deaths caused by cholera increased to 6,435 in the Caribbean country since October 2010.The Haitian Health Ministry said the number of people infected with cholera almost reached half a million, although the ministry repeated the epidemic was decreasing.The report said 455,727 people had been treated due to cholera, and 242,205 had to be hospitalized.The western province of Artibonite suffered the plague most with 1,196 deaths. The southwest province of Nippes registered the smallest death toll of 181.Meanwhile, in the Haitian capital Port-au-Prince, 221 people have been killed since October 2010 when the epidemic first broke out in central Haiti.The epidemic is supposedly due to the spill of dregs from a Nepalese camp, which is part of the UN Stabilization Mission in Haiti (MINUSTAH).The Dominican Republic, a country neighboring the island country Haiti to the east, has also been suffering the disease since November 2010, which has killed at least 135 people there.