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WASHINGTON, May 11 (Xinhua) -- Johns Hopkins University researchers have demonstrated that human liver cells derived from adult cells coaxed into an embryonic state can engraft and begin regenerating liver tissue in mice with chronic liver damage.The work, published Wednesday in the journal Science Translational Medicine, suggests that liver cells derived from so- called "induced-pluripotent stem cells (iPSCs)" could one day be used as an alternative to liver transplant in patients with serious liver diseases, bypassing long waiting lists for organs and concerns about immune system rejection of donated tissue."Our findings provide a foundation for producing functional liver cells for patients who suffer liver diseases and are in need of transplantation," says Yoon-Young Jang, assistant professor of oncology at the Johns Hopkins Kimmel Cancer Center. "iPSC-derived liver cells not only can be generated in large amounts, but also can be tailored to each patient, preventing immune-rejection problems associated with liver transplants from unmatched donors or embryonic stem cells." A microsopic view shows human embryonic stem cells in various stages of differentiation into liver cells in this photo taken at Stanford University and released by the California Institute for Regenerative Medicine, March 9, 2009iPSCs are made from adult cells that have been genetically reprogrammed to revert to an embryonic stem cell-like state, with the ability to transform into different cell types. Human iPSCs can be generated from various tissues, including skin, blood and liver cells.Although the liver can regenerate in the body, end-stage liver failure caused by diseases like cirrhosis and cancers eventually destroy the liver's regenerative ability, Jang says. Currently, the only option for those patients is to receive a liver organ or liver cell transplant, a supply problem given the severe shortage of donor liver tissue for transplantation. In addition, mature liver cells and adult liver stem cells are difficult to isolate or grow in the laboratory, she says. By contrast, iPSCs can be made from a tiny amount of many kinds of tissue; and the embryonic stem- like iPSCs can grow in laboratory cultures indefinitely.For the study, Jang and colleagues generated human iPSCs from a variety of adult human cells, including liver cells, fibroblasts ( connective tissue cells), bone marrow stem cells and skin cells. They found that though the iPSCs overall were molecularly similar to each other and to embryonic stem cells, they retained a distinct molecular "signature" inherited from the cell of origin.

TAIPEI, Jan. 29 (Xinhua) -- Nora Sun, granddaughter of Sun Yat-sen, the forerunner of China's revolution to end feudalism, died Saturday afternoon in a Taipei hospital, about one month after being injured in a car accident.Sun, 72, was severely injured in a car crash while on her way to an airport near Taipei on Jan. 1. She was in stable condition after several operations, but her condition abruptly deteriorated Saturday afternoon, according to hospital officials, without giving additional details.Sun, who spent most of her time in Shanghai, came to Taipei to attend the Flora Expo. While returning to Taoyuan International Airport near Taipei the black sedan Sun was riding in crashed head-on into an oncoming vehicle, described as a red car. Sun had planned to return to Hong Kong that day.Sun's car had been driven by a friend. The driver of the red car, who was believed to be speeding, according to police, died on the spot. Sun, her friend, and an injured passenger in the red car were immediately transported to a hospital. .Sun is the youngest daughter of Sun Fo, son of Sun Yat-sen, the leader of the 1911 Revolution that ended imperial rule in China.

BEIJING, Feb. 8 (Xinhua) -- China respects the results of south Sudan referendum, which was announced Monday, Chinese Foreign Ministry spokesman Hong Lei said Tuesday.Hong made the remarks in a statement concerning China's view on the results of the referendum."China respects the choice of Sudan people and appreciates the unremitting efforts of both the north and the south to promote the peace process between the two sides," Hong Lei said."China hopes the two sides will continue to resolve controversial issues through dialogue and consultation in line with the principle of mutual understanding and mutual accommodation," Hong said."China expects full implementation of the Comprehensive Peace Agreement(CPA) as well as long peace and stability in Sudan."The referendum, conducted from Jan. 9 to 15, was a major condition of the CPA, which ended a two-decade civil war between the two sides.The South Sudan Referendum Commission Monday announced the final results of the referendum saying that 98.83 percent of the voters had voted for separation.

BEIJING, Feb. 14 (Xinhua) -- A recent circular of China's film and television watchdog to cut smoking scenes in films and TV dramas has received welcome from supporters of tobacco control.Xu Guihua, deputy head of China Association on Tobacco Control (CATC), a non-profit organization, said the order of the State Administration of Radio, Film and Television (SARFT) demonstrates government determination to protect public health rights."Frequent smoking scenes in films and TV dramas do not accord with China's stance on tobacco control and mislead the public, especially the youth," said the SARFT in a recent circular.Tobacco brands or signs and smoking scenes with juveniles present should not be allowed to appear in films or TV dramas, it said, adding that scenes which have to show smoking should "last as short as possible."Hailing the order, Xu said the communication through media including movies and TV is among those factors that can influence people's attitude toward smoking.Deng Haihua, a spokesman with China's Ministry of Health, also said the SARFT's move will help prevent people, especially the young, from being misled by smoking scenes on screens.In a survey report issued in August 2010, the CATC said it found smoking scenes in 31 movies and 28 TV series after monitoring 40 Chinese movies and 30 local TV series.Another survey by Beijing Municipal Center for Disease Control and Prevention also showed students tend to follow the fashion after seeing actors smoke on TV or in films.China has more than 300 million smokers and 540 million more suffering from secondhand smoke.What is especially worrisome is that 11.5 percent of the country's juvenile smoke and the ratio is even increasing, according to experts.

BEIJING, March 10 (Xinhuanet) -- The price of preventing preterm labor is about to rise drastically in the U.S. next week.A drug for high-risk pregnant women costs about 10 to 20 dollars per injection. Next week, the price will shoot up to 1,500 dollars a dose, according to media reports Wednesday.This means the total cost during a pregnancy could be as much as 30,000 dollars.The massive increase comes after KV Pharmaceutical of St. Louis won an exclusive government license to produce the drug, known as Makena.The drug, a form of progesterone given as a weekly shot, has been made cheaply for years by unlicensed chemists.The March of Dimes and many obstetricians supported the move because it means quality will be more consistent and it will be easier to get, but none of them has anticipated the sharp price hike.Doctors and campaign groups have been caught out by the move, saying that the price hike may deter low-income women from getting the drug, leading to more premature births.