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BEIJING, August 1 (Xinhuanet) -- U.S. researchers have discovered a genetic mutation unique to African Americans that links to heighten their asthma risk, according to reports published on Sunday in the journal Nature Genetics.Researchers of University of Chicago found a gene, PYHIN1, and its variations may account for asthma risk in people of African descent. In their study, they examined data from nine previous genome-wide association studies, totaling more than 2 million single nucleotide polymorphisms in 3,246 asthma patients and 3,385 control patient, 1,702 patient-parent groupings, 355 family-based cases, and 468 family-based controls.In the study, the researchers found that between 26 percent and 29 percent of people of African-descent carried at least one copy of the gene. In particular, one polymorphism of the gene was 34 percent more likely found in African-American and Afro-Caribbean people with asthma. More interestingly, this variant of the gene is rarely found in Caucasian people and in Latino population, it was found in less than 5 percent.This new variant is part of a family of genes linked with the body's response to viral infections. It is thought to be involved in interferon signaling, which could influence the occurrence of asthma.The team stressed that each gene variant on its own plays only a small role in increasing asthma risk, but that risk could be multiplied when combined with other risk genes and with environmental factors.
BEIJING, August 1 (Xinhuanet) -- U.S. researchers have discovered a genetic mutation unique to African Americans that links to heighten their asthma risk, according to reports published on Sunday in the journal Nature Genetics.Researchers of University of Chicago found a gene, PYHIN1, and its variations may account for asthma risk in people of African descent. In their study, they examined data from nine previous genome-wide association studies, totaling more than 2 million single nucleotide polymorphisms in 3,246 asthma patients and 3,385 control patient, 1,702 patient-parent groupings, 355 family-based cases, and 468 family-based controls.In the study, the researchers found that between 26 percent and 29 percent of people of African-descent carried at least one copy of the gene. In particular, one polymorphism of the gene was 34 percent more likely found in African-American and Afro-Caribbean people with asthma. More interestingly, this variant of the gene is rarely found in Caucasian people and in Latino population, it was found in less than 5 percent.This new variant is part of a family of genes linked with the body's response to viral infections. It is thought to be involved in interferon signaling, which could influence the occurrence of asthma.The team stressed that each gene variant on its own plays only a small role in increasing asthma risk, but that risk could be multiplied when combined with other risk genes and with environmental factors.
BEIJING, June 29 (Xinhuanet) -- Twitter Inc. co-founders Biz Stone and Evan Williams said they are moving on from the microblogging service, media reports said Wednesday.“The Twitter crew and its leadership team have grown incredibly productive,” Stone said on the blog. “I’ve decided that the most effective use of my time is to get out of the way until I’m called upon to be of some specific use.”The two will continue to advise Twitter on strategic matters, but devote the lions' share of their time to The Obvious Corporation, Stone said.Obvious was first created by Williams to buy back a company from investors that he and Stone failed to sell about six years ago, Stone said. The two began working together after leaving Google in 2005.The company will also be run by Jason Goldman, a former Twitter executive, Stone said.
BEIJING, Sep. 1 (Xinhuanet) -- A campaign is being launched across U.S. to help lovers of sugar drinks reduce their habit by the Center for Science in the Public Interest.This campaign is based on the findings of a new survey conducted by CDC (Centers for Disease Control)."Men drink more than women, and teens and young adults drink the most," said Cynthia L. Ogden who is an epidemiologist at the CDC's National Center for Health Statistics.The campaign is called "Life's Sweeter with Fewer Sugary Drinks." And it aims to decrease intake of soda and sugary drinks down to the American Heart Association recommendation of fewer than three cans per person per week.Sugary drink intake in the U.S. has increased over the last 30 years, which has been linked with weight gain, obesity, poor diet, and type 2 diabetes.So far, the cities signing on include Boston, Chicago and Los Angeles.