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They have traveled for days on foot and by bus. They are tired, hungry and desperate for a better life.President Donald Trump described the Central American migrants traveling in a caravan through Mexico as dangerous but many of them are women and children.As many of them stay south of the border to find work there and some 200 or so migrants continue their journey into the US, here's a look at some of their stories: 428

Today @Mintmobile is launching unlimited for just AND bringing back Rick Moranis. Suck it, 2020. pic.twitter.com/N1sl7mYchF— Ryan Reynolds (@VancityReynolds) September 9, 2020 187

Too few new antibiotics are under development to combat the threat of multidrug-resistant infections, according to a new World Health Organization report published Tuesday. Adding to the concern: It is likely that the speed of increasing resistance will outpace the slow drug development process.As of May, a total of 51 antibiotics and 11 biologicals -- medical products often made from natural sources -- are being developed, the new report said."The idea is that biologicals could replace use of antibiotics, which could help in overcoming the resistance problem," Peter Beyer, an author of the report and senior adviser to the WHO's Department of Essential Medicines and Health Products, wrote in an email.Seemingly, this large number of potential new drugs should suffice, yet it is not nearly enough.First, just 33 of the antibiotics in the pipeline target priority pathogens. This year, the WHO published a list of a dozen "priority pathogens": 12 separate families of antibiotic-resistant bacteria that pose the greatest threat to human health.Among the priority pathogens is a drug-resistant tuberculosis, which kills about 250,000 people around the world each year, and a variety of multidrug resistant strains -- Acinetobacter, Pseudomonas and various Enterobacteriaceae -- which are responsible for infections in hospitals and nursing homes and among patients whose care requires ventilators and catheters.Of the 33 potential medicines for treating priority bug infections, only eight are innovative treatments. The other 25 are simple modifications of existing families of antibiotics. At best, then, the 25 will serve as short-term solutions since it is expected bacteria will quickly adapt to and resist these new (though somewhat familiar) drugs, according to the WHO."It is difficult to speculate why companies develop specific new medicines," Beyer noted. "But in general many new treatments do not necessarily constitute advances over existing treatments."TB infections require a combination of at least three antibiotics, according to the new report, yet only seven of the new TB medicines are even in clinical trials. Soon, there will be a serious lack of treatment options for this infection, the report warns.The same is true for gram-negative pathogens, which can cause severe, often deadly infections typically in hospitals and nursing homes.Gram-negative bacteria have more complex cell walls than gram-positive, explained Beyer. "In a nutshell, it is more complex to develop a novel antibiotic that can penetrate the complex gram-negative cell wall and stay inside the bacterium," he wrote.Finally, the WHO sees too few oral antibiotics being developed. These are necessary "to target the critical priority pathogens (and) be accessible in low- and middle-income countries," Beyer noted.To address the problem of developing new antibiotics, the WHO and the Drugs for Neglected Diseases Initiative set up the Global Antibiotic Research and Development Partnership. However, new drugs alone cannot combat the threat of antimicrobial resistance. The WHO is also working to improve infection prevention and control while developing guidance for the responsible use of antibiotics."Always seek medical advice before taking antibiotics and then always follow the advice of the health-care professional," Beyer noted.The new report is a "fantastic (and very useful!) summary" of the antibiotic situation, wrote Bill Hanage, an associate professor of epidemiology at Harvard T.H. Chan School of Public Health, in an email. Hanage, who has also published studies of antibiotic resistance, was not involved in the new report.Although the risk of getting a completely resistant infection is low in the United States, about 2 million people each year become infected with "resistant enough" bacteria that are harder to treat, Hanage said. And every year, more than 20,000 people die of these infections."More resistant infections don't just mean you or someone you care about is more likely to die from one, they also mean healthcare will get even more expensive," Hanage said. "Many of the procedures we take for granted in medicine, from cancer treatments to surgeries, depend on our ability to handle infections that happen in the course of treatment."The number of new drugs in development is simply not enough, he said."The great majority will not make it into the hands of doctors or your treatment," Hanage wrote. "As the report states, for drugs to be used in humans they have to pass 3 hurdles, the phase 1, 2 and 3 trials. Drugs entering that pipeline have just a 14% chance of getting all the way through to be used in humans." 4676

There's some misunderstanding about medical exemptions to wearing masks.A legal expert tells us the Americans with Disabilities Act (ADA) makes it so businesses must make reasonable accommodations to everyone. The key word there is reasonable.“The problem with what's going on right now and some of the things that have been going around the internet, is that the advice, kind of spurious advice that's being put forth is to use the provision for reasonable accommodation as a sword rather than as a shield,” said David Tarrien, an associate professor at WMU-Cooley Law School.Tarrien says the conditions that qualify as a mask exemption have a smaller scope than many realize. For example, he says asthma patients likely do not fall under that scope. But later stages of pulmonary respiratory disease, emphysema, or a serious mobility issue can be "legitimate" reasons.Furthermore, you could face repercussions for lying.“If they're claiming that they have a disability and they don't have a disability, if that is found out, then there are criminal and civil penalties for that,” said Tarrien.As for privacy concerns, Tarrien says store employees are allowed to ask customers why they're not wearing a mask. If you refuse to answer, they may refuse entry.Even if you give a legitimate reason to not wear a mask, you may still be refused entry. That's because the ADA does not apply if there's a “direct threat” to someone's health or safety.Tarrien says HIPPA privacy laws also do not apply in this kind of situation. That only protects your information from being shared inappropriately among medical facilities. 1623

This holiday season won't be the same without "A Charlie Brown Christmas" on network TV.But after viewer outrage, it is coming back to TV — for just one night.Viewers looking for "A Charlie Brown Christmas" won't find it on ABC or CBS this year for the first time in 50 years.Apple this fall snapped up all the Peanuts specials (including "It's the Great Pumpkin, Charlie Brown"), and they will be streaming on Apple TV Plus from now on.You can just see Apple jumping up and down in a little wooden booth like Lucy Van Pelt, saying "I just love the sound of money!"Where you can still see it freeBut if you don't want to pay a month to subscribe to Apple TV Plus, you still have several free options to watch the holiday favorite.Apple announced "A Charlie Brown Christmas" will be available to stream on the platform for free from Dec. 11 to Dec. 13.Just go visit the Apple TV Plus website(tv.apple.com) on a TV, smartphone or laptop and search for the special.You should not be required to enter a credit card to watch the special between Dec. 11 and 13, according to Apple Insider. A credit card is required for a 7-day free trial of the entire streaming service on all other days.What about those who don't stream?But from the doesn't that stink file — Apple's free offer doesn't help those who still use cable or antenna TV.After thousands of viewer complaints, Apple recently announced it is allowing PBS stations nationwide to air the show on Dec. 13. It will air at 7:30 pm on most stations, but check your local PBS listings.DVDs of "A Charlie Brown Christmas" are also available at Walmart, Target, and Amazon for between - for those who want to watch the show on demand without a streaming service. The only thing missing: The old Dolly Madison snack cake commercials featuring Lucy and Linus and the gang that used to air during the broadcast.Streaming TV is the future, but some traditions are best enjoyed the old fashioned way, with the whole family gathered in front of the big TV screen. As always, don't waste your money.______________________________Don't Waste Your Money" is a registered trademark of Scripps Media, Inc. ("Scripps").Like" John Matarese Money on FacebookFollow John on Instagram @johnmataresemoneyFollow John on Twitter (@JohnMatarese)For more consumer news and money saving advice, go to www.dontwasteyourmoney.com 2369