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SORRENTO VALLEY, Calif. (KGTV) - Another San Diego-based company is moving forward on developing a vaccine for the coronavirus. Sorrento Therapeutics is working on several projects that they believe could lead to viable vaccines or treatments. One of them was announced on Monday. Sorrento Therapeutics said it was partnering with Boston-based Smartpharm to create a gene-encoded antibody vaccine. “In the effort to more quickly resolve the global COVID-19 crisis, our company has initiated a rapidly accelerated program for the identification of potent neutralizing antibodies against SARS-CoV-2 coronavirus antigens that may be used for either treatment or prophylaxis,” said Henry Ji, CEO of Sorrento Therapeutics. Sorrento Therapeutics is also working on another vaccine called the I-Cell project. That vaccine uses a decoy virus to activate a person’s immune system to train it to attack the real virus. It’s also developing a protein called COVIDTRAP that can bind to the receptors on the coronavirus, thus blocking it from being able to bind to the receptors on healthy human cells. If proven succesful, it could be used as a treatment or preventative measure.How long will it take for them to be ready?“That all depends on what leeway the FDA gives us,” said Mark Brunswick, Senior Vice President of Regulatory Affairs at Sorrento Therapeutics. If they can get fast tracked, he estimates they can start clinical trials in 2 months, as opposed to 9-12 months normally. 1483

Software engineer Raymond Berger begins his work day at 5 a.m., before the sun comes up over Hawaii.Rising early is necessary because the company he works for is in New York City, five hours ahead of Maui, where he is renting a home with a backyard that’s near the beach.“It’s a little hard with the time zone difference,” he said. “But generally I have a much better quality of life.”The pandemic is giving many workers the freedom to do their jobs from anywhere. Now that Hawaii’s economy is reeling from dramatically fewer tourists, a group of state officials and community leaders wants more people like Berger to help provide an alternative to relying on short-term visitors.Coinciding with the approach of winter in other parts of the U.S., “Movers & Shakas” — a reference to the Hawaii term for the “hang loose” hand gesture — launches Sunday as a campaign to attract former residents and those from elsewhere to set up remote offices with a view. They’re touting Hawaii’s paradisiacal and safety attributes: among the lowest rates per capita of COVID-19 infections in the country.The first 50 applicants approved starting Sunday receive a free, roundtrip ticket to Honolulu. Applicants pledge to respect Hawaii’s culture and natural resources and participants must commit several hours a week to helping a local nonprofit.It didn’t take much to convince Abbey Tizzano to leave behind her Austin, Texas, apartment to join four Silicon Valley friends in a rented house in Kahala, Honolulu’s version of Beverly Hills.She had never been to Hawaii before. She booked a one-way ticket, arrived in September and quarantined for 14 days, complying with the state’s rules at the time for arriving travelers. She’s keeping Central time zone hours while working in account management for a software company, allowing her to end the work day early enough to enjoy long hikes along mountain ridges or walk five minutes to the beach.“It’s like I live two lives right now. There’s the corporate side for ... the early mornings,” Tizzano said. “And then there’s just like the Hawaii lifestyle after I get off work around noon or 1 p.m.”Neighbors tell the remote workers they’re a welcome change from the bachelor and bachelorette parties the luxury home normally hosts, she said.Tizzano wonders what other locals think of them: “Are they appreciative of people coming that want to help stimulate the economy or are they concerned that they’re going to raise housing prices more and stuff like that?”Housing is a real concern in a state where there’s an affordable housing crisis, said Nicole Woo, a policy analyst for Hawaii Appleseed Center for Law and Economic Justice.She worries that if their presence remains beyond the pandemic and if they come in larger numbers, they could start pushing property values even higher.Lifelong Kauai resident Jonathon Medeiros felt uncomfortable when he saw an airline ad luring remote workers to Hawaii.The remote worker campaign just feels to him like another kind of tourism. “We just get portrayed as this paradise, a place for you to come and play,” he said. “And there’s such privilege involved in that attitude.”One focus of the campaign sounds appealing to Medeiros, a public high school teacher: An opportunity for those who grew up in Hawaii to come home without having to take the pay cuts that are often required to work here.“I see so many of my students, they graduate and many of them leave and never come back,” he said, “because they don’t see Kauai as a place where they can make a life.”Richard Matsui grew up in Honolulu. After high school, he left for the U.S. mainland and Asia for educational and career opportunities.As CEO of of kWh Analytics, he never expected to be able to leave California’s Bay Area and still be able to run the company.The pandemic shut down child care options in San Francisco for his baby born in January. He and his wife planned to come to Honolulu for a month so that his mother could help with the baby. A month turned into two and then six.“If there’s an opportunity now to take mainland salaries and our mainland jobs and to execute them well from Hawaii, I do think that Hawaii has a once-in-a-lifetime opportunity to diversify the economy and ... take advantage of the fact that our core strength is Hawaii is a tremendously wonderful place to live and to raise kids,” he said.The idea behind the campaign started with wanting more people like Matsui to come home, said Jason Higa, CEO of FCH Enterprises, parent company of Hawaii’s popular Zippy’s restaurants.Then the group started thinking about broadening it to others.With the impacts on housing in mind, Higa said the group included a vacation rental company that’s sitting on a large inventory of vacant properties normally rented by tourists.Wissam Ali-Ahmad, a software solution architect from San Jose, California, is renting a Kauai condo that’s normally marketed to vacationers.He has picked up side projects as a consultant for local food trucks and restaurants to help the small businesses improve their contactless services.“I feel like I’m a guest here, and I have to contribute as much as possible,” he said.Many Hawaii neighborhoods are overrun with illegal short-term vacation rentals, and having those properties occupied legally by longer-term tenants is appealing, said Ryan Ozawa, communications director for local tech company, Hawaii Information Service.“What I like about the idea of, say, a cabal of Twitter employees all moving to Kailua is that one, they bring their jobs with them, so you’re not talking about displacement in that regard,” he said. “But for all of the things that we want, which is local sales tax, groceries, electric bill, et cetera, you know, those paychecks from San Francisco get spent in Hawaii.”The Honolulu suburb of Kailua has been struggling with how to manage an influx of short-term vacation rentals. It’s where Julia Miller, who works for a company that provides payroll services for small businesses, her Google employee husband and their two toddlers, ended up last month when they left Northern California’s dreary weather and fires.“We do feel really grateful that we were able to come here and be welcome,” she said. “We want to do our part in keeping Hawaii safe.”While the Millers plan to stay four to six months, others are looking at Hawaii as a longer-term remote workplace.Software engineer Gil Tene and his wife, an intensive care unit doctor, bought a house in September in Hanalei, Kauai’s most desirable beach town of multimillion-dollar homes.They plan to split their time between Hanalei and Palo Alto, California, so they looked for a property with remote working in mind. They settled on a five-bedroom house — enough rooms for Tene to work in, his wife to see patients virtually in and their daughter to study in.“What you look for in a place you intend to work from is very different than when you want to vacation,” he said. 6954

SOUTH HAVEN, Mich. -- Those stuck at home and going stir crazy many have begun venturing out this summer. Air and car travel have been steadily increasing in recent months and visits to lakefront resorts have been on the rise. But some worry the economic boost in tourism could be short-lived.Located along the shores of Lake Michigan, the resort town of South Haven is a drivable oasis for busy urban dwellers looking for a quick escape like Naperville, Illinois, resident Edward Marcin.“People are friendly. The water here the boats… it’s almost like going to New England in two and a half hours,” says Marcin.Scott Reinert, the executive director of the South Haven, Van Buren County Convention and Visitor’s Bureau says the tourism economy here brings in about million of revenue to the area each year.“Lodging represents a little over 20 percent of the total spend when visitors come in,” he says.But the pandemic shutdown wiped out 10 weeks of business. Revenues for the beachfront community were down 90 percent.“They essentially put us out of business,” says John Marple. He owns the Old Harbor Inn in South Haven.Forced to lay off his entire staff, Marple lost 20% of his gross income.Federal stimulus dollars he says helped him keep from going under.But once the state allowed for reopening in early June, business began booming. It took just days for rooms to sell out completely through July and even into august.“The online reservations just blew up. I had the highest sales month I ever had in June of this year,” says Marple.It’s so busy Marple has removed the inn from travel sites like Expedia and Booking.com.Today, the town is bustling with tourists. The beaches are completely packed. Housekeeping can barely keep up with the enhanced disinfecting process.“Right now, it takes us approximately 45 minutes longer to properly prepare a room for a new guest by doing all the sanitation,” says Marple.Door stickers now indicate when a room has been cleaned and that no one has been inside. But rising COVID-19 cases and hospitalizations in many states are changing consumer attitudes towards travel plans.“With so many visitors coming in from in some cases hotspots from around the state or around the Midwest,” says Reinert. “You know, how long can we stay safe?”According to a travel survey conducted this month by Longwoods International, 76% of travelers say the will change their plans because of coronavirus. That’s up from 69% at the beginning of June. And 45% say they will cancel trips completely. That’s up from 37% in June.“The past week for sure we have seen a rash of cancellations,” says Marple.While the current increase in tourism has helped recover some losses, another shut down Marple worries could be devastating to the seasonal businesses here.“I do worry that business may not return like it has in the past. I think this is going to be an issue for quite some time," he said. 2927

Simone Biles has added another milestone to her historic gymnastics career with a gold medal at the 2018 United States Gymnastics Championships on Sunday.Per The United States Olympic Team, Biles is the first woman ever with five U.S. Gymnastics all-around titles.Per TeamUSA.org's Brandon Penny, Biles became the oldest woman (21) to win the all-around crown since Linda Metheny Mulvihill shared the gold with Joan Moore Gnat in 1971.Since making her debut at the U.S. Gymnastics Championships in 2013, Biles has been an unstoppable force. She has taken gold in the all-around in each of her five appearances at the event—she didn't participate last year while taking a hiatus—and has won 16 gold medals across every discipline.After taking all of 2017 off from competition, Biles began training last October with an eye on competing for Team USA at the 2020 Olympics. Her first event back was an overwhelming success with two years to go before the Tokyo Games. 991

Several U.S. airlines are boosting their flight schedules ahead of the Thanksgiving in anticipation of a surge in travelers flying during the holiday amid the coronavirus pandemic.An American Airlines spokesperson told FOX Business that they plan to increase its flights from Nov. 24-25 and Nov. 28-30 by 15%, bumping up from an average of 3,500 flights per day to more than 4,000 flights over the holiday.United Airlines said that they would boost capacity, with the carrier predicting Thanksgiving week will be its busiest since March, so they are planning to add more than 1,400 domestic flights that week.The carrier added that they'd "swap in larger aircraft" to accommodate any last-minute travel demands.In December, United said it'll add more than 140 daily flights and increase capacity on more than 350 routes as passengers look to travel during the holidays that month.JetBlue and Delta Airlines are also adding more flights in anticipation of passengers traveling during the Thanksgiving holiday.JetBlue said 25 flights from New York City and surrounding areas to Florida, California, and in the Caribbean, such as Port-au-Prince, San Juan, Santiago, and Santo Domingo, will be added between Nov. 20 and Nov. 30.Meanwhile, Delta said it'll increase to over 3,800 peak-day flights per day during Thanksgiving.Delta said it'll increase service to leisure destinations in Hawaii, Mexico, and Florida. 1417