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Supporters of right-to-try argue that the legislation is needed because most terminal patients are too sick to be selected to participate in clinical trials and it takes too long for promising treatments to be approved.Joffe argued that the right-to-try approach to providing access to unapproved drugs early in their development could put patients in harm's way, as patients receiving the drug are often in very fragile health, doctors often lack the information needed to administer the drugs safely, and little may be known about their risks and benefits, he said.Joffe pointed to certain stem cell therapies as treatment approaches that appear promising but have turned dangerous when unregulated."Another thing I'm worried about is that there's going to be a bunch of shady actors that are going to pop up that are going to start to try to take advantage of the right-to-try law to say 'we can provide these sort of experimental therapies, if you want to call them that, to patients without needing to go through the FDA,'" Joffe said."We've already seen some of that in the stem cell clinics popping up around the country that try to provide stem cell treatments for a host of problems: eye problems, heart problems," he said. "While there are legitimate efforts to develop effective stem cell therapies, a lot of these clinics that are popping up around the country that are poorly regulated are taking people's money and they are hurting people."On the other hand, the treatments available under right-to-try laws are already in clinical trials, Coleman said, adding that "this law isn't replacing the existing FDA expanded access program; it's just opening up another avenue.""No person is going to be forced to take an investigational drug. No doctor is going to be forced to request an investigational drug, and no drug company is forced to provide an investigational drug, if they don't think it's the right fit for a patient," she said."It's only for people who say, 'I understand the risk. I know this drug is not fully approved. It may not help me, but my doctor and the drug company think it could, and I want to try,'" she said. "Basically, if the FDA says that a drug is safe enough to be used in trials on humans, then it's safe enough for a dying person to make their own choice about whether or not they would like to try it when they can't get into a clinical trial."  2395

That means, if a man believes he was discriminated against or experienced a hostile work environment because he is a man, he can allege sex discrimination, Bornstein said in an email. "'Because of sex' also includes 'because of gender stereotypes' — meaning feminine or masculine dress or behavior." 299

Small closure due to the threat of new volcanic activity: https://t.co/qgMGhIWUD4 pic.twitter.com/9sIVre0fPb— Hawaii Volcanoes NPS (@Volcanoes_NPS) May 3, 2018 159

The “message with the subject line “Emergency Alert” went out to over 3 million mobile phone users in San Diego and it read: “TEST of the CA Earthquake Warning System. No action required. THIS IS A TEST.”RELATED: Earthquake warning system expanding across SoCal 261

Sister Cynthia Borman, an educator as well, was also something of a handy-woman. She was the fixer-upper of the church. Sciano says if you needed something fixed, she was the one to turn to. 190