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WASHINGTON, Sept. 14 (Xinhua) -- Controlling diabetes may someday involve mining stem cells from the lining of the uterus, Yale School of Medicine researchers report in a new study published Wednesday in the journal Molecular Therapy. The team treated diabetes in mice by converting cells from the uterine lining into insulin-producing cells.The endometrium or uterine lining, is a source of adult stem cells. These cells generate uterine tissue each month as part of the menstrual cycle. Like other stem cells, however, they can divide to form other kinds of cells.Led by Yale Professor Hugh Taylor, the researchers bathed endometrial stem cells in cultures containing special nutrients and growth factors. Responding to these substances, the endometrial stem cells adopted the characteristics of beta cells in the pancreas that produce insulin. Over the course of a three- week incubation process, the endometrial stem cells took on the shape of beta cells and began to make proteins typically made by beta cells. Some of these cells also produced insulin.After a meal, the body breaks food down into components like the sugar glucose, which then circulates in the blood. In response, beta cells release insulin, which allows the body's cells to take in the circulating glucose. In this study, Taylor and his team exposed the mature stem cells to glucose and found that, like typical beta cells, the cultured cells responded by producing insulin. The team then injected diabetic mice with the mature, insulin-making stem cells. The mice had few working beta cells and very high levels of blood glucose.Mice that did not receive the stem cell therapy continued having high blood sugar levels, developed cataracts and were lethargic. In contrast, mice that received the cell therapy were active and did not develop cataracts, but the animals' blood sugar levels remained higher than normal.The Yale team's findings suggest that endometrial stem cells could be used to develop insulin-producing islet cells, which are found in the pancreas. These islet cells could then be used to advance the study of islet cell transplantation to treat people with diabetes.Taylor said in a statement that the next step in the research will be to verify how long this treatment remains effective.
SAN FRANCISCO, Sept. 13 (Xinhua) -- Intel and Google on Tuesday announced a partnership to enable the world's largest chip maker's architecture on the search giant's products, saying that an Intel chip-based Android smartphone will hit the market in the first half of 2012.In a joint press release, the two companies said the future versions of Android mobile operating system will support Intel's low power Atom processors, in addition to other architectures.At the Intel Developer Forum in San Francisco on Tuesday, Intel Chief Executive Officer Paul Otellini said the Intel smartphone chip is code-named Medfield and based on the company's own PC- based computer architecture.Otellini said multiple vendors around the world will launch the Medfield-based Android smartphones in the first half of 2012.Andy Rubin, senior vice president of mobile at Google, came on stage at the close of Otellini's keynote to hail the joint initiatives between the two companies.Intel has been struggling to get a bite of the booming market of smartphones and tablets. Most of the current mobile devices use chips based on architecture from ARM Holdings, which are considered more power efficient than Intel's products. Nokia had planned to ship smartphones with Intel chips this year, but it shifted to ARM-based phones with Windows Phone 7 system.Otellini said Intel will eventually have an advantage in supplying smartphone chips as the business is not established in terms of the final winner and performance of the products keeps growing.
BERLIN, June 5 (Xinhua) -- German authority said on Sunday that bean sprouts might be the "most convincing" source for the E. coli outbreak which has killed 22 people and infected more than 2,000 in the Europe.Gert Lindemann, Agriculture Minister of the state Lower Saxony, told reporters in a press conference that restaurants and food outlets where the cases of E. coli had been reported all had received shipments of the particular bean sprouts.A related company in the Uelzen region has been shut down and its products have been recalled, he said."It is the most convincing... source for the E. coli outbreak," Lindemann said. Although a conclusive laboratory analysis will not come out until Monday, current indications were strong enough to issue a public warning, he said.Authorities have been racing to track down the source of the pathogen since the outbreak, which has infected people in 12 countries - all of whom had once traveled in northern Germany. More than 600 of those infected have developed Hemolytic Uremic Syndrome (HUS), a potentially deadly complication attacking the kidneys.The source of E.coli was first thought to be the cucumbers from Spain, which has caused huge loses for Spain farmers. However, this conclusion was overthrown by Laboratory tests in Hamburg on Tuesday.
BEIJING, July 15 (Xinhua) -- The Chinese Academy of Agricultural Sciences (CAAS) announced Friday that a group of international scientists has finished sequencing the genetic code of the potato.The Potato Genome Sequencing Consortium (PGSC), which is led by Chinese scientists and made up of 97 researchers from 14 countries, has sequenced the complete potato genome and published a report of its findings in the latest issue of the scientific journal Nature, said the CAAS.The research took six years and revealed that the potato contains about 39,000 genes, said the CAAS.Qu Dongyu, a potato farming specialist with the Crop Science Society of China and a promoter of the PGSC, said the study helped discover genes that define the growth and insect resistance of potatoes.The sequenced genome will enable scientists to create new varieties of potato that are high in yield and quality and more resistant to insects and diseases, he said.Huang Sanwen, a researcher with the CAAS and one of the three corresponding authors of the report, said the sequencing will also allow potato breeders to accelerate the breeding process of new seeds from 10 to 12 years to about 5 years.China is the world's top potato grower, with its farmers planting potatoes on nearly 90 million mu (6 million hectares) of land each year. The average yield per mu stands at 1,000 kg, only one-third of that harvested by countries with advanced technologies, Qu said.
LOS ANGELES, June 5 (Xinhua) -- A latest study has found no evidence that screening for ovarian cancer may reduce the risk of dying from the disease, it was reported on Sunday.Screening, however, does increase the likelihood of unnecessary invasive procedures, according to researchers at the University of Utah.The researchers presented their findings at an on-going meeting of the American Society of Clinical Oncology in Chicago, The Los Angeles Times said.Researchers studied 78,216 women, ages 55 to 74, who participated in the National Cancer Institute's Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial. Half of the women received the usual care from their OB-gyns, and half received a CA 125 screening every year for six years and an ultrasound every year for four years. They were then followed for a maximum of 12 years.The researchers observed 212 ovarian cancers in the screened group and 176 in the normal care group. There were 118 ovarian cancer deaths in the screened group and 100 in the normal care group. The differences were not statistically significant. Overall, there were 2,924 deaths from all causes in the screened group and 2,914 in the normal care group.But the researchers also observed that 3,285 women had false- positive diagnoses from the screening. Among those, 1,080 underwent surgery that included an oophorectomy (surgical removal of one or both ovaries). Fifteen percent of those who had surgery developed major complications as a result. Overall, 1,771 women in the screened group (7.7 percent) had an oophorectomy, compared with 1,304 in the normal care group (5.8 percent)."We conclude that annual screening for ovarian cancer ... does not reduce disease-specific mortality in women at average risk for ovarian cancer but does increase invasive medical procedures and associated harms," the researchers said in the study.New data presented at the meeting also showed that the widely used cancer drug Avastin can improve treatment of ovarian cancer, The Times said.About 21,880 American women are diagnosed with ovarian cancer each year and about 13,850 die from it, according to the American Cancer Society. Because it produces few symptoms, the disease is typically not diagnosed until it has become advanced and spread throughout the body. As a result, five-year survival is only about 30 percent, and the disease is one of the five most deadly cancers among women. Being able to detect the cancer at an earlier stage when it might be more curable could thus, theoretically, improve the survival rate.The tests most commonly used to detect ovarian cancer include a transvaginal ultrasound to look for tumor masses and a blood test that screens for increased levels of a tumor marker called CA 125.