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New York, Connecticut and New Jersey asked Wednesday for travelers from states with high coronavirus infection rates to go into quarantine for 14 days in a bid to preserve hard-fought gains as caseloads rise elsewhere in the country.“We now have to make sure the rates continue to drop,” New York Gov. Andrew Cuomo said Wednesday at a briefing in New York City, joined via video by Govs. Phil Murphy of New Jersey and Ned Lamont of Connecticut, both fellow Democrats. “We also have to make sure the virus doesn’t come on a plane again.”What was presented as a “travel advisory” that starts Thursday affects three adjacent Northeastern states that managed to check the spread of the virus this spring as New York City became a hot spot for the pandemic.Travelers from more than a half-dozen states, including Florida and Texas, are currently impacted. The quarantine will last two weeks from the time of last contact within the identified state.The announcement comes as summer travel to the states’ beaches, parks and other attractions — not to mention New York City — would normally swing into high gear.It also marks a flip-flop in the COVID-19 battle since March, when Florida Gov. Ron DeSantis and Texas Gov. Greg Abbott, both Republicans, separately issued orders requiring people flying in from the New York tri-state area, where cases were surging, to quarantine for 14 days.Now, Florida and Texas are among the struggling states being eyed warily by the three northern governors.“As Governor DeSantis said on Saturday, Governors have a prerogative to do what they need to do,” press secretary Cody McCloud said. “He just asks that Floridians not be quarantined in the nursing homes in New York.”Murphy called a quarantine the smart thing.“We have taken our people, the three of us, these three states, to hell and back,” Murphy said. “The last thing we need to do right now is subject our folks to another round.”The states will relay the quarantine message on highways, at airports, and through websites and social media. Lamont signed an executive order on Wednesday evening requiring such messages be posted at all major points of entry into the state and at the state’s airports. He said the governors plan to also ask hotels and vacation rental companies to tell guests from affected states.Lamont’s order also allows the state’s public health commissioner to make exceptions for essential workers and for “other extraordinary circumstances” when a quarantine is not possible.Enforcement will vary by state. The Cuomo administration said violators in New York will be subject to mandatory quarantine and face fines from ,000 to ,000. Violators could be discovered at business meetings or during a traffic stop, he said.It was not clear what, if any, penalties violators in New Jersey and Connecticut will face.Lamont described the quarantine as “urgent guidance.” Murphy called it a “strong advisory ... to do the right thing.”The quarantine applies to people coming from states with a positive test rate higher than 10 per 100,000 residents on a seven-day average, or with a 10% or higher positivity rate over seven days.As of Wednesday, states over the threshold were Alabama, Arkansas, Arizona, Florida, North Carolina, South Carolina, Washington, Utah and Texas, Cuomo said.Washington Gov. Jay Inslee said later Wednesday that his state was erroneously included on the list.A spokeswoman for Cuomo, Caitlin Girouard, said there had been an initial discrepancy with Washington’s reporting, but “they have since corrected it and we have removed them from the list of states under travel advisory.”The order appears to apply to President Donald Trump, who was in Arizona on Tuesday and is slated to go to Bedminster, New Jersey, this weekend.White House spokesman Judd Deere said in an email Wednesday that standard procedures were in place in Arizona to ensure the president did not come into contact with anyone who was symptomatic or had not been tested.“It could come back and we can have a second wave arriving by jet airplane a second time,” Lamont said. “And right now, they wouldn’t necessarily be coming from China. They could be coming from one of six or seven or eight states that have a very high positivity rate.”___Contributing to this report were Associated Press writers Marina Villeneuve in Albany, N.Y.; Susan Haigh in Hartford, Connecticut; and Mike Catalini in Trenton, N.J. 4421

New research suggests that antibodies the immune system makes to fight the new coronavirus may only last a few months in people with mild illness, but that doesn’t mean protection also is gone or that it won’t be possible to develop an effective vaccine.“Infection with this coronavirus does not necessarily generate lifetime immunity,” but antibodies are only part of the story, said Dr. Buddy Creech, an infectious disease specialist at Vanderbilt University. He had no role in the work, published Tuesday in the New England Journal of Medicine.The immune system remembers how to make fresh antibodies if needed and other parts of it also can mount an attack, he said.Antibodies are proteins that white blood cells called B cells make to bind to the virus and help eliminate it. The earliest ones are fairly crude but as infection goes on, the immune system becomes trained to focus its attack and to make more precise antibodies.Dr. Otto Yang and others at the University of California, Los Angeles, measured these more precise antibodies in 30 patients diagnosed with COVID-19 and four housemates presumed to have the disease. Their average age was 43 and most had mild symptoms.Researchers found that the antibodies had a half-life of 73 days, which means that half of them would be gone after that much time. It dovetails with a previous report from China also suggesting antibodies quickly fade.The results “call for caution regarding antibody-based ‘immunity passports,’ herd immunity, and perhaps vaccine durability,” the California authors write.That’s true, Creech said, but other parts of the immune system also help confer protection. Besides churning out antibodies, B cells develop a memory so they know how to do that again if needed.“They would get called into action very quickly when there’s a new exposure to the virus. It’s as if they lie dormant, just waiting,” he said.Other white blood cells called T cells also are better able to attack the virus the next time they see it, Creech said.Although circulating antibodies may not last long, what we need to know is if and how people remake antibodies if exposed to the coronavirus again and if they protect against another infection, Alison Criss, an immunologist at the University of Virginia, wrote in an email. “We also need to know if there is a protective T cell response” that reappears.Vaccines, which provoke the immune system to make antibodies, might give longer-lasting protection than natural infection because they use purified versions of what stimulates that response, she noted.Creech agreed.“This shouldn’t dissuade us from pursuing a vaccine,” he said. “Antibodies are only a part of the story.”___Marilynn Marchione can be followed on Twitter at http://twitter.com/MMarchioneAP___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 2967

NEW YORK (AP) — Keith Raniere, a self-improvement guru whose organization NXIVM attracted millionaires and actresses among its adherents, was sentenced Tuesday to 120 years in prison.The 60-year-old was convicted of charges accusing him of turning some of his followers into sex slaves branded with his initials.The court proceeding in Brooklyn culminates several years of revelations about the organization, which charged people thousands of dollars for self improvement courses.Those people included Hollywood celebrities and others willing to endure humiliation and pledge obedience for Raniere’s vision of how to pursue perfection.Prosecutors said Raniere led what amounted to a criminal enterprise. Co-conspirators helped recruit and groom sexual partners for him.Raniere’s sentencing comes about a month after Clare Bronfman, a wealthy benefactor of his, was sentenced to seven years in prison in the case.The Seagram’s liquor fortune heir was taken into custody to begin her 81-month sentence immediately after her appearance in federal court in Brooklyn on Sept. 30.Bronfman admitted in a guilty plea last year that she committed credit card fraud on behalf of Raniere. 1185

NEW YORK (AP) — Police have made an arrest in a mystery that's been stopping New Yorkers in their tracks for months: a wave of subway trains grinding to a halt because someone pulled the emergency brake.Isaiah Thompson, 23, of Brooklyn, was arrested late Thursday after police publicized video of a man they say pulled the emergency brake on a train in Manhattan during the Tuesday evening rush hour.Thompson was awaiting arraignment Friday on charges related to the Tuesday incident. He's also accused of committing a lewd act in the subway.Police are investigating whether he's behind about 40 other brake-pulling incidents that have cascaded into hundreds of delayed trains — and thousands of frustrated commuters — since February. Police on Thursday released images and video of a man they say rode on the outside of a car for several stops before entering the car and pulling its emergency brake and fleeing.Chief Edward Delatorre, of the NYPD's transit division, said police believe Thompson is responsible for "several incidents where he endangered subway riders (and) disrupted passenger train service."Thompson's record includes more than a dozen arrests, mostly for subway-related incidents. Police say he's claimed to get a thrill out of "subway surfing" and enjoys causing havoc in the transit system.It wasn't clear if Thompson had a lawyer who could comment on his behalf.Police believe someone has been using a key to get into an unoccupied motorman car and then engage the emergency brake."Let this be a reminder that anyone who intentionally disrupts the subway, endangering our employees and customers, will be sought by the police and caught," Transit Authority President Andy Byford said in a statement Friday.Byford said whoever is responsible for the series of brake-pulling incidents "should face a lengthy prison term and the strictest possible penalties." He's been pushing to ban people who repeatedly commit offenses in the subway.The video of Tuesday's incident involved a man police say rode on the outside of a northbound 2 train for several stops before entering the car, pulling its emergency brake and fleeing.The man was wearing a Nike T-shirt with the slogan: "Swag Don't Come Cheap." 2227

NEW YORK (AP) — Apple is the first U.S. company to boast a market value of trillion, just two years after it became the first to reach trillion. Apple shares have gained nearly 60% this year as the company overcame the shutdown of factories in China that produce the iPhone and the closure of its retail sales amid the coronavirus pandemic. The company’s hugely loyal customer base trust its products so much that they continued to buy iPhones and other devices online while stuck at home. Apple recently reported blowout earnings for the April-June quarter.Apple has been at the vanguard of a group of Big Tech companies that are increasingly taking over people’s lives — and the stock market. Just five companies — Apple, Microsoft, Amazon, Facebook and Google’s parent company — account for nearly 23% of the S&P 500’s entire value. 853

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