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For the first time in more than a decade, a new treatment to improve brain function for Alzheimer’s disease has been submitted to the Food and Drug Administration (FDA) for review.This was after the drug trial was stopped and then a second look revealed some promising results.The Waterhouse family has seen the impact of Alzheimer’s firsthand.Gina and Steve Waterhouse have been a team most of their lives. They’ve been married for 43 years and ran several businesses together. Then in 2016, things started to change. Gina didn’t notice anything but employees at the family's businesses did.“I wasn't remembering some of the stuff I was supposed to be doing,” said Gina.Gina was diagnosed with early Alzheimer's disease that year.“They said, 'well you can come back in a year. We will check and see how you're doing, or we have a drug trial if you're interested,'” said Gina.Gina and Steve spent the next two and a half years at the Mayo Clinic, where Gina eventually got high doses of the drug aducanumab.Steve started to notice Gina was remembering more things and reported it back to doctors.“He just smiled and said, 'let me tell you what we're seeing. We're seeing cognitive improvement. And it’s the first time in my career.' These doctors said in their career that we've ever seen it,” said Steve.“He was so excited,” said Gina.Then in 2019, the drug trial suddenly ended. Gina says she felt like she’s gone downhill a little since it did.Rebecca Edelmeyer, PhD, with the Alzheimer’s Association, says the trial stopped early based on a futility analysis.“It was a statistical analysis that was done by the Biogen team, predicting that the trial would not actually be successful,” said Edelmeyer.Edelmeyer says then upon a second look at the trial data, they found that those people on the highest dose of the drug were seeing improvement in their brain function. She called it a very important moment for the Alzheimer’s research community.Now, the government will determine whether or not the drug is safe and effective enough to use.Steve mentioned there were some possible side effects like bleeding of the brain, but Gina did not experience any.Meanwhile, Gina can no longer take the drug. She and Steve have decided to retire.“We just decided tomorrow has to come today and we're having a great time. We're loving life,” said Gina.You can learn more about aducanumab here. 2394

Finding the right child care can be a frustrating -- and expensive -- process for parents around the world, from New York to Nairobi.Access to adequate child care for all has become a "global" need, said Shelley Clark, a demographer and professor of sociology at McGill University in Canada, who has studied child care and other family dynamics."We can think of iconic images like The Atlantic monthly cover of the mom carrying the kid in the briefcase to work and how absurd that's supposed to be to us, but then when we think of women in lower-income countries, you think of the mom selling goods at the market with a kid strapped to her back, and you think, 'Well, that's not a problem for her, because she can easily combine child care and work,' " Clark said."There's this perception out there that for the kinds of work that women do in lower-income countries, it's easier to combine child care and work," she said. "The fact is, it's quite challenging for these moms, also."Clark added that families in lower-income countries spend a significant chunk of their income -- about 17% of some women's average earnings -- on child care services, similar to those in wealthier countries.Families living across 30 wealthy nations in the Organisation for Economic Co-operation and Development spend on average about 15% of their net income on child care costs, according to a 2016 report from the group, an association of 35 countries founded to improve economic development and social well-being around the world.Yet the percentage of a family's income spent on child care costs varies drastically by country: Couples spend 33.8% in the United Kingdom, but in Korea, Austria, Greece and Hungary, couples spend less than 4% due to government benefits and programs. Those findings came from the OECD's database on tax and benefits across countries compared with average net income of families in those countries.Here is a sampling of what child care looks like around the world. 1984

Former FBI Director James Comey on Sunday called the House Intelligence Committee Republicans' year-long Russia investigation "a wreck" that damaged relationships with the intelligence community and the federal court that grants warrants to surveil foreigners.The committee released a redacted version of the GOP report on the panel's Russia probe Friday, which found no evidence of collusion between the Trump campaign and Russia in its attempt to influence the 2016 presidential election. The report also disputed the intelligence community's assessment that Russian President Vladimir Putin tried to help elect Donald Trump.The committee also released a redacted Democratic dissent document that said collusion exists and that Republicans failed to investigate key aspects of the matter.Asked on NBC's "Meet the Press" whether the committee served "a good investigative purpose," Comey responded: "Not that I can see," adding that the probe became politicized "and it wrecked the committee, and it damaged relationships with the FISA Court, the intelligence communities. It's just a wreck."Comey said the resulting GOP report "strikes me as a political document."Trump tweeted about the report on Friday evening, saying it backs his claims that there is no truth to the allegations that his campaign colluded with Russia in Moscow's attempt to interfere in the election."House Intelligence Committee rules that there was NO COLLUSION between the Trump Campaign and Russia," Trump wrote. "As I have been saying all along, it is all a big Hoax by the Democrats based on payments and lies. There should never have been a Special Councel (sic) appointed. Witch Hunt!" Trump wrote on Twitter.Comey disputed the President's assertions when asked during the interview Sunday whether they matched his views."That is not my understanding of what the facts were before I left the FBI, and I think the most important piece of work is the one the special counsel's doing now," Comey said.Comey, who was fired by Trump in May, is on a publicity tour to promote his newly published memoir, "A Higher Loyalty: Truth, Lies, and Leadership," which paints a critical portrait?of the President. In the book, Comey calles Trump "unethical" and "untethered to the truth" and compares his presidency to a "forest fire."The book prompted a furious response from Trump, who has repeatedly attacked the former FBI director on Twitter, calling him a "leaker" and a "liar."Asked on Sunday whether he would consider Trump a credible witness if the President were to sit down for an interview with special counsel Robert Mueller, Comey said: "I have serious doubts about his credibility.""Whether he were under oath or not?" host Chuck Todd asked?"Correct," Comey said. "And sometimes people who have serious credibility problems can tell the truth when they realize the consequences of not telling the truth in an interview or in the grand jury would be dire. But you would have to go in with a healthy sense that he might lie to you." 3083

Former President George H.W. Bush is facing allegations that he squeezed a teenager's buttocks in 2003.In an interview with Time magazine published Monday, Roslyn Corrigan said she was 16 years old when Bush, then 79, touched her inappropriately at a November 2003 event in The Woodlands, Texas, office of the CIA, where her father had gathered with fellow intelligence officers and family members to meet Bush.Corrigan told the magazine Bush groped her buttocks as she and her mother, Sari Young, posed for a photograph with the former president. 555

Former Vice President Joe Biden canceled a planned appearance in Illinois this week because he is sick and "under doctor's orders not to travel," according to state Democrats."Everyone who knows Vice President Biden knows that he gives our party and our country his all, but unfortunately he is sick and is under doctor's orders not to travel," Illinois Democratic County Chairs' Association President Doug House said in a statement posted to Facebook Tuesday night.Biden, 75, was scheduled as a keynote speaker for the Illinois Democrats County Chairs' Association brunch in Springfield, Illinois. The event kicks off Democrats' Day at the Illinois State Fair."The cancellation is of course disappointing, but it is clear that the circumstances are simply unavoidable," House said.House added, "We all hope he gets well soon and I'm sure he'll be back campaigning for Democrats in Illinois and across the country in no time."A spokesman for Biden said the former vice president is simply under the weather and will "be fine in a few days." The spokesman would not comment on the record about Biden's condition.Biden has been crisscrossing the country campaigning with Democrats candidates ahead of the midterm elections but also fueling speculation that he'll seek the Democratic presidential nomination in 2020. 1321