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The first participant in a clinical trial for a vaccine to protect against the new coronavirus will receive an experimental dose on Monday, according to a government official.The National Institutes of Health is funding the trial, which is taking place at the Kaiser Permanente Washington Health Research Institute in Seattle. The official who disclosed plans for the first participant spoke on condition of anonymity because the move has not been publicly announced.Public health officials say it will take a year to 18 months to fully validate any potential vaccine. Testing will begin with 45 young, healthy volunteers with different doses of shots co-developed by NIH and Moderna Inc. There’s no chance participants could get infected from the shots, because they don’t contain the virus itself. The goal is purely to check that the vaccines show no worrisome side effects, setting the stage for larger tests.Dozens of research groups around the world are racing to create a vaccine as COVID-19 cases continue to grow. Importantly, they’re pursuing different types of vaccines — shots developed from new technologies that not only are faster to produce than traditional inoculations but might prove more potent. Some researchers even aim for temporary vaccines, such as shots that might guard people’s health a month or two at a time while longer-lasting protection is developed.Also in the works: Inovio Pharmaceuticals aims to begin safety tests of its vaccine candidate next month in a few dozen volunteers at the University of Pennsylvania and a testing center in Kansas City, Missouri, followed by a similar study in China and South Korea.Even if initial safety tests go well, “you’re talking about a year to a year and a half” before any vaccine could be ready for widespread use, according to Dr. Anthony Fauci, director of NIH’s National Institute of Allergy and Infectious Diseases.That still would be a record-setting pace. But manufacturers know the wait — required because it takes additional studies of thousands of people to tell if a vaccine truly protects and does no harm — is hard for a frightened public.President Donald Trump has been pushing for swift action on a vaccine, saying in recent days that the work is “moving along very quickly” and he hopes to see a vaccine “relatively soon.”Today, there are no proven treatments. In China, scientists have been testing a combination of HIV drugs against the new coronavirus, as well as an experimental drug named remdesivir that was in development to fight Ebola. In the U.S., the University of Nebraska Medical Center also began testing remdesivir in some Americans who were found to have COVID-19 after being evacuated from a cruise ship in Japan.For most people, the new coronavirus causes only mild or moderate symptoms, such as fever and cough. For some, especially older adults and people with existing health problems, it can cause more severe illness, including pneumonia. The worldwide outbreak has sickened more than 156,000 people and left more than 5,800 dead. The death toll in the United States is more than 50, while infections neared 3,000 across 49 states and the District of Columbia. The vast majority of people recover. According to the World Health Organization, people with mild illness recover in about two weeks, while those with more severe illness may take three weeks to six weeks to recover.___The Associated Press receives support for health and science coverage from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 3597

The Federal Reserve on Wednesday voted to raise interest rates despite new signs of economic softening and weeks of market volatility.Central bankers unanimously agreed under Chairman Jerome Powell to lift the federal funds rate, which controls the cost of mortgages, credit cards and other borrowing, to a range of 2.25% and 2.5%.Interest rates have increased seven times since President Donald Trump took office. Four of those increases have been under Powell.The policy decision comes even as Trump called on the Fed to move cautiously "before they make yet another mistake," shortly before policy makers began their two-day policy-setting meeting in Washington on Tuesday. 688

The Minnesota National Guard confirmed that three guardsmen died after a UH-60 Blackhawk helicopter went down near St. Cloud, Minnesota, on Thursday. There were no survivors on board the helicopter.The Minnesota National Guard said that they lost contact with the crew around 2:05 p.m. CT. The National Guard was conducting a maintenance test flight on the Blackhawk."Our Minnesota National Guard family is devastated by the deaths of these soldiers," said Maj. Gen. Jon Jensen, the Adjutant General of the Minnesota National Guard. "Our priority right now is ensuring that our families are taken care of."The identities of the guardsmen are being withheld pending next of kin notification. The National Guard said an investigation is currently being conducted. 773

The Boy Scouts of America urged victims to come forward Tuesday as the historic, 110-year-old organization filed for bankruptcy protection in the first step toward creating a huge compensation fund for potentially thousands of men who were molested as youngsters decades ago by scoutmasters or other leaders.The Scouts resorted to Chapter 11 in hopes of surviving a barrage of lawsuits, many of them made possible by recent changes in state laws to allow people to sue over long-ago sexual abuse.Bankruptcy will enable the organization to put those cases on hold for now and continue operating. But ultimately the Boy Scouts could be forced to sell some of their vast property holdings, including campgrounds and hiking trails, to raise money for a victims’ fund that could top billion.The Boy Scouts estimated 1,000 to 5,000 victims will seek compensation.“The BSA encourages victims to come forward to file a claim as the bankruptcy process moves forward,” the organization said in a statement.James Kretschmer of Houston, one of those suing, said he was molested by a Scout leader in the mid-1970s in the Spokane, Washington, area. The bankruptcy, he said, “is a shame because at its core and what it was supposed to be, the Boy Scouts is a beautiful organization.”“But you know, anything can be corrupted,” he added. “And if they’re not going to protect the people that they’ve entrusted with the children, then shut it down and move on.”More than 12,000 boys have been molested by 7,800 abusers since the 1920s, according to Boy Scout files revealed in court papers.Evan Smola said two new victims had already called his law office in Chicago on Tuesday morning, bringing the firm’s total to 319.“The opportunity to tell your story is a cathartic and healing experience,” Smola said. “It’s very painful when they actually do it, but getting it off your chest is a big step.”It will be up to the court to set a deadline for filing claims. The amount of money each victim will receive is likely to depend on what assets are turned over and how many people come forward.The filing in Wilmington, Delaware, sets in motion what could be one of the biggest, most complex bankruptcies ever seen, given the Scouts’ 50-state presence. The organization listed assets of billion to billion and liabilities of 0 million to billion.“We are outraged that there have been times when individuals took advantage of our programs to harm innocent children,” said Roger Mosby, the Boy Scouts’ president and CEO. “While we know nothing can undo the tragic abuse that victims suffered, we believe the Chapter 11 process, with the proposed trust structure, will provide equitable compensation to all victims while maintaining the BSA’s important mission.”The Boy Scouts are the latest major American institution to face a heavy price over sexual abuse. Roman Catholic dioceses across the country and schools such as Penn State and Michigan State have paid out hundreds of millions of dollars in recent years.The bankruptcy represents a painful turn for an organization that has been a pillar of American civic life for generations and a training ground for future leaders. Achieving the rank of Eagle Scout has long been a proud accomplishment that politicians, businessmen, astronauts and others put on their resumes and in their official biographies.“I’m sad for all the victims who were preyed upon by people entrusted with their care. I’m sad that no amount of money will undo their trauma,” said Jackson Cooper, an Eagle Scout who is now a prosecutor in Louisville, Kentucky. “Whatever consequences come for BSA are no concern of mine. I only hope, if they continue to operate, they build robust systems to protect the young people in their care.”The Boy Scouts’ finances have been strained in recent years by declining membership and sex-abuse settlements.The number of youths taking part in scouting has dropped below 2 million, down from a peak of more than 4 million during the 1970s. Its membership rolls took a big hit Jan. 1 when The Church of Jesus Christ of Latter-day Saints cut ties and withdrew more than 400,000 scouts in favor of programs of its own.The financial outlook worsened last year after New York, Arizona, New Jersey and California relaxed their statutes of limitations to make it easier for victims to file claims. Teams of lawyers across the U.S. have been signing up clients by the hundreds to sue the Boy Scouts.Most of the new cases date to the 1960s, ’70s and ’80s, before the Boy Scouts adopted mandatory criminal background checks, abuse-prevention training for all staff and volunteers, and a rule that two or more adult leaders must be present during all activities. Many of the lawsuits accuse the group of negligence and cover-ups.Wayne Perry, a member of the organization’s national board and past president, said Scout families won’t notice any differences as a result of the bankruptcy. He touted the protections now in place for young people.“Today, we are really, really good. Were we always good? No, nobody was good 50 years ago, 40 years ago, 30 years ago,” Perry said.Amid the crush of lawsuits, the Scouts recently mortgaged some of their major properties, including their national headquarters in Irving, Texas, and the 140,000-acre Philmont Ranch in New Mexico.One unanswered question is whether the Boy Scouts’ 261 local councils — and their campgrounds and other assets — will be dragged into the case, even though the Boy Scouts said the councils are legally separate entities and they were not part of the bankruptcy filing.Mike Pfau, a Seattle-based attorney whose firm is representing scores of men nationwide, said the plaintiffs may go after the local councils’ property holdings, too.“We believe the real property held by the local councils may be worth significantly more than the Boy Scouts’ assets,” he said. He said one question will be whether the Boy Scouts transferred property to their local councils to try to put it out of the reach of those suing.Perry said he hopes the court remembers that the Boy Scouts are teaching leadership and life skills to children. “You have to take into account the balancing of the victims, but (also) the fact that the kids today who are joining Scouting had nothing to with those bad behaviors of criminal acts of perpetrators who are long gone,” he said.Plaintiffs’ attorneys trace the Boy Scouts’ fall to 2010, when a jury awarded a former Scout nearly million in a lawsuit in Portland, Oregon. The trial led the Oregon Supreme Court to release 20,000 pages of confidential Boy Scout files on 1,200 people after The Associated Press and other news organizations fought for their disclosure.Until last spring, the organization had insisted it never knowingly allowed a predator to work with youths. But in May, the AP reported that attorneys for abuse victims had identified multiple cases in which known predators were allowed to return to leadership posts. The next day, the Boy Scouts acknowledged the truth.___McCombs reported from Salt Lake City. Associated Press video journalist John Mone also contributed to this story. 7147

The Dow fell more than 800 points Wednesday after the bond market, for the first time in over a decade, flashed a warning signal that has an eerily accurate track record for predicting recessions.Here's what happened: The 10-year Treasury bond yield fell below 1.6% Wednesday morning, dropping just below the yield of the 2-year Treasury bond. It marked the first time since 2007 that 10-year bond yields fell below 2-year yields.US stocks fell as investors sold stock in companies and moved it into bonds. The Dow was about 2.8% lower. The broader S&P 500 was also down 2.8% and the Nasdaq sank 3.1% Wednesday.CNN Business' Fear and Greed Index signaled investors were fearful. The VIX volatility index spiked 26%.Investors are on edge because the German economy shrank in the second quarter, and the US-China trade war still looms large over markets despite the latest truce. Industrial production in China grew at the weakest rate in 17 years in July.As the global economy sputters, investors are plowing money into long-term US bonds. The 30-year Treasury yield fell to 2.05%, the lowest rate on record.Government bonds — particularly US Treasuries — are classic "safe-haven" assets that investors like to hold in their portfolios when they're nervous about the economy. Stocks, by contrast, are riskier assets that tend to be more volatile during economic slowdowns.Gold, another safe-haven asset, rose 1% Wednesday.Here's what this all means: Normally, long-term bonds pay out more than short-term bonds because investors demand to be paid more to tie up their money for a long time. But that key "yield curve" inverted on Wednesday. That means investors are nervous about the near-term prospects for the US economy. Bonds and yields trade in opposite directions, so yields sink when investors buy bonds.Part of the yield curve has been inverted for several months. In March, the yield on the 3-month Treasury bill rose above the rate on the 10-year Treasury note for the first time since 2007. It inverted again on July 24 and has remained negative. But Wednesday marked the first time in over a decade that the "main" yield curve — the 2-year / 10-year ratio — had inverted.That spooked Wall Street, because an inversion of the 2/10 curve has preceded every recession in modern history. That doesn't mean a recession is imminent, however: The Great Recession started nearly two years after the December 2005 yield-curve inversion.William Foster, Moody's lead US analyst, predicts the US economy will avoid a recession in 2019 and in 2020, despite the yield curve inversion's warning sign. He expects growth to slow in the second half this year into 2020.The US economy remains strong: Unemployment is historically low, consumer spending is booming, and the financial system is healthy."Even though we're discouraged by the yield curve's shape right now, we see few signs of danger ahead," said John Lynch, LPL Research chief investment strategist, in a blog post.Stocks have grown volatile lately, with the Dow plunging and rising more than 350 points in each session this week. But the yield curve inversion doesn't mean the stock market is about to collapse. The S&P 500 has rallied 22% on average between the first time a yield curve inverts and the start of a recession, Lynch noted.Following the last yield curve inversion in 2005, stocks rose for 12 straight months. 3400