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WASHINGTON, Oct. 9 (Xinhua) -- U.S. researchers have found a way to block, in an animal model, the damaging inflammation that contributes to many disease conditions. In their report receiving early online publication Sunday in Nature Biotechnology, researchers describe using small interfering RNA technology to silence the biochemical signals that attract a particular group of inflammatory cells to areas of tissue damage."The white blood cells known as monocytes play a critical role in the early stages of the immune response," says Matthias Nahrendorf, of the Massachusetts General Hospital (MGH) Center for Systems Biology, the paper's senior author. "We now know there are two subsets of monocytes -- an inflammatory subset that defends against pathogens and a reparative subset that supports healing. But if the inflammatory response is excessive, it can block the healing process and exacerbate conditions such as heart disease and cancer."Cells damaged by injury or disease release a cocktail of chemicals called cytokines that attract immune cells to the site of the damage. Inflammatory monocytes are guided to sites of tissue injury by a receptor protein called CCR2, and the MGH-led team devised a strategy targeting that molecule to block the inflammatory process but not the action of the reparative monocytes.Small interfering RNA (siRNA) technology prevents production of specific proteins by binding to associated messenger RNA molecules and preventing their translation. However, the technique requires extreme precision in developing the right siRNA molecule and delivering it to the correct cellular location.To make sure that their siRNA preparation targeted the right monocytes, researchers first confirmed that its use reduced levels of CCR2 in monocytes and increased levels of the fragments produced when siRNA binds to its target. They then showed that monocytes from mice treated with the siRNA preparation were unable to migrate towards CCR2's usual molecular target. Experiments in animal models of several important diseases showed that the siRNA preparation reduced the amount of cardiac muscle damaged by a heart attack, reduced the size and the number of inflammatory cells in atherosclerotic plaques and in lymphomas, and improved the survival of transplanted pancreatic islets."These inflammatory monocytes are involved in almost every major disease," Nahrendorf explains. "Anti-inflammatory drugs currently on the market hit every inflammatory cell in the body, which can produce unwanted side effects. This new siRNA treatment doesn't affect inflammatory cells that don't rely on the CCR2 receptor. That makes a big difference."
SAN FRANCISCO, Nov. 7 (Xinhua) -- Google on Monday added a highly-anticipated service to its Google+ social network, allowing businesses and brands to set up their own pages on the site.Named "Google+ Page," the service is a further challenge to its rival Facebook's fan pages, which has become a major promotion strategy for many business brands over the past several years.Unlike Facebook, Google will not charge businesses and organizations for using the scheme, and will not put ads on the pages. The service is expected to enhance the tech giant's other businesses like search and mobile advertising.Some big brand names, such as Burberry, the Barcelona football club and the Muppets, have already set up their pages.Google noted it will not pass on personal data.In addition to big brands, Google also wants small businesses that have or do not have their own websites to use Google+ Pages as their default presences.According to a report by Ad Age Digital, Google+ Pages will soon be location-aware, allowing local businesses to send offers and deals to mobile phones.According to Google, more than 40 million people have opened an account with its social network, which was launched in June. Although the network is growing very quickly, some analysts said it still has a long way to go to become a major threat to Facebook, which has more than 800 million users.
BEIJING, Jan. 22 (Xinhua) -- China restored 23,000 hectares of wetlands in 2011, according to the latest figures from the State Forestry Administration (SFA).An SFA spokesman said China reinforced wetland protection in 2011 by increasing subsidies in protecting wetlands. In the year the country carried out 42 wetland protection projects, increased 330,000 hectares of protected wetland areas, added four wetlands of international importance and 68 national wetland parks.The spokesman said in 2012 the country will further step up wetland protection and restoration, finish the second national wetland resources investigation and carry out pilot projects in assessing healthy conditions of the wetland ecological system.So far China has built more than 550 wetland natural reserves, 37 wetlands of international importance, which were listed in the Ramsar international wetland convention, and 100 national wetland parks. About half of the country's natural wetlands have been brought under effective protection, the SFA said.
SINGAPORE, Dec. 18 (Xinhua) -- Two Chinese Navy ships called at Singapore's Changi port on Sunday on their way back to China from an escort mission in the Gulf of Aden and the waters off Somali.The destroyer Wuhan and the frigate Yulin were part of the ninth flotilla dispatched by China in July to guard commercial ships in the troubled waters against pirates.They are stopping over in Singapore for three days to replenish fuel, water and other logistic supplies, officials said.The task force will also have exchanges with the Singapore side on anti-pirate efforts, and visit Singapore's Information Fusion Center, which is aimed to promote collaboration and information sharing in maritime security.The Chinese sailors were received at the port in Changi Naval Base on Sunday morning by Colonel Tan Kai Cheong, commander of the 3rd Flotilla, Singapore Navy; Chinese Ambassador to Singapore Wei Wei and other Chinese diplomats, as well as representatives of Chinese companies and the Chinese community in Singapore.Guan Jianguo, commander of the Chinese flotilla, said the task force left the port of Zhanjiang in Guangdong province on July 2. The two Chinese naval warships made port calls in Kuwait and Oman for friendly visits before stopping over at Singapore.The Chinese flotilla escorted 280 commercial vessels, including both Chinese and foreign ships, during the five months of the escort mission in the Gulf of Aden and the waters off Somali.Sixteen of the escorted vessels were Singapore-registered.The Chinese task force and the anti-pirate flotilla dispatched by Singapore also organized exchange visits, and the commanders of the two flotillas also met for exchanges.The Chinese Navy ships will leave Singapore on Tuesday for their home country.
ADDIS ABABA, Oct. 22 (Xinhua) -- China on Saturday delivered portion of the first batch of emergency food assistance to Ethiopia.Wei Hongtian, Charge d'Affairs at the Chinese Embassy in Ethiopia, handed over the assistance certificate to Wondirad Mandefro, Ethiopian State Minster of Agriculture, in a ceremony held at the Office of the Ethiopian Disaster Risk Management Food Security Sector (DRMFSS) in Addis Ababa, Ethiopia.The handover was witnessed by Ahmed Shide, Ethiopian State Minister of Finance and Economic Development, and Qian Zhaogang, Economic Counselor at the Chinese Embassy in Ethiopia as well as officials and diplomats from the two countries.The charge d'affairs said the Chinese government has decided to provide Ethiopia with two batches of gratis emergency food aid valued at some 24 million U.S. dollars, as part of humanitarian assistance to the people affected by drought in the Horn of Africa region, about which the international community is concerned much.Months ago, China pledged to provide humanitarian aid to drought affected people in Ethiopia, Kenya and Djibouti.The 2011 drought in the Horn of Africa region has affected livelihoods of over 12 million people in countries of the region including Ethiopia.In this move, China has delivered large quantities of wheat to Ethiopia, and it is put in the central warehouse in Adama town, 90 km away from Addis Ababa, as the first batch of the 8,139.4 tons of wheat and 715.15 tons of rice donated by the government of China, said Ethiopian State Minister of Agriculture.According to the minister, the Chinese government has pledged around 20,000 tons of emergency food valued at 24 million dollars.Wei said China attaches great importance to the agriculture development and the food security in Africa. He said China has engaged itself in various agricultural cooperations with African countries including Ethiopia, in different channels."In the future, besides food assistance, China's agricultural cooperation with Africa will focus on technology demonstration, personnel training, infrastructure construction, promotion of agricultural production and trade, and experience sharing agriculture development," said the Charge d'Affairs.The rest portion and the other batch of the emergency food assistance pledged by China is expected to come in November and December.Wei assured that the rest batches of emergency food aid would come to Ethiopia on schedule. The Ethiopian state minister said the Chinese government is one of those donors that demonstrated its strong friendship with the Ethiopian government and its people by extending appreciable humanitarian support at critical time."The recent donation of 100, 000 U. S. dollars by a Chinese private company, Huajin Group Ltd, for food aid is a manifestation that even private companies join us in our efforts to containing problems associated with such natural disasters," said Wondirad."Despite a steady economic growth achieved these past eight years in Ethiopia that reached an average of 11 percent annually and our continued efforts to maintain and accelerate the momentum through the GTP, we are confronted by climate change induced disasters, of which drought remains the major one," said the minister."While reducing disaster risk and vulnerabilities through development interventions, the government of Ethiopia in collaboration with its partners is taking all the necessary measures towards further enhancing its early warning and response system with the view to reducing potential impacts of disasters, including that of drought enhanced preparedness and provision of timely and appropriate responses."The government of the People's Republic of China has been one of our major development partners supporting us in all these efforts," he added.The state minister commended the Chinese government and its people for standing with Ethiopia shoulder to shoulder at the critical time by donating appreciable size of emergency food aid.