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The Trump Administration pushed through a million contract to study whether the active ingredient in Pepcid is an effective treatment for Covid-19. That contract is now under scrutiny after a government whistleblower accused a senior administration official of rushing the deal through without the scientific oversight necessary for such a large federal award. The Food and Drug Administration gave the clinical trial speedy approval even as a top agency official worried that daily injections of high doses of famotidine for already sick patients pushed the levels of what was considered safe “to the limits,” internal government emails show. And the doctors who initially pushed the Pepcid idea are locked in a battle for credit and sniping over allegations of scientific misconduct.The origins of the interest in famotidine are under dispute, but there were reports out of China that patients who took the drug survived the virus, while patients who took other heartburn medications were not surviving. Initial observational studies in the U.S. were promising, however scientists urged more research was needed. Meantime, the trial itself that was part of the million contract is on pause due to a shortage of hospitalized COVID-19 patients in New York, delaying it indefinitely. A vaccine or effective treatment could be available before the study is complete. 1380
The road to the White House clearly goes through the state of Michigan as both Joe Biden and Donald Trump have been actively campaigning in the state.Michigan has been a state hard-hit economically in recent years as the once thriving auto industry Nationally, the number of auto jobs has declined amid the pandemic. The auto industry has lost nearly 100,000 jobs this year.At the start of the century, there were more than 1.3 million US auto jobs. When Barack Obama took office, that number had dropped by 50%. During his tenure, the auto industry regained a portion of those jobs lost.But any gains from a revamped trade agreement had yet to be realized in the auto industry based on Bureau of Labor Statistics figures. On Thursday, Joe Biden said in an interview with CNN’s Jake Tapper the new USMCA agreement that replaced NAFTA is an upgrade, but failed to give President Donald Trump for securing the agreement."But look what the overall trade policy has done even with NAFTA. We now have this gigantic deficit in trade with Mexico. Not because NAFTA wasn't made better, because overall trade policy and how he deals with it made everything worse," Biden said.Biden was asked whether Trump should be given credit for the USMCA. Biden said the Obama White House was unable to renegotiate NAFTA because of Congress. For the first two years of the Obama administration, both the House and Senate were held by Democrats.“Because we had a Republican Congress that wouldn't go along with us renegotiating,” Biden told Tapper.In 2008, both Biden and Obama campaigned on changing the US trade agreement between Mexico and Canada. The USMCA, which became effective this year, was amended by Congress, but ultimately won bipartisan support from leaders of both party.The interview with Tapper was taped in Michigan and aired hours before Trump held a campaign rally in the state.On Monday, Trump said, “Biden supported NAFTA. He supported China’s entry into the World Trade Organization. Two disasters. The most disastrous trade deals in history, both of them. I can’t tell you which was worse; they were both terrible.” 2125

The Sanderson Sisters from "Hocus Pocus" are back and ready to put a spell on you this Halloween.Bette Midler, Sarah Jessica Parker, and Kathy Najimy are reuniting as The Sanderson Sisters from the cult classic "Hocus Pocus." The sisters will be treating us to a virtual event on Oct. 30. And it's all for a good cause.According to the New York Restoration Project (NYRP) website, tickets for the "In Search of the Sanderson Sisters: A Hocus Pocus Hulaween Takeover" are .All the money raised will benefit the nonprofit NYRP, which Midler started in 1995. They restore parks and plant trees in New York City.Midler tweeted a picture of all three actresses together as Winifred, Mary, and Sarah Sanderson. 715
The US has reported more deaths from the coronavirus on Wednesday than in any other single day during the pandemic, according to data from Johns Hopkins University.According to Johns Hopkins’ figures, local health officials reported 3,157 deaths from COVID-19 on Wednesday, shattering the previous record of 2,607 set in April.The marker comes as CDC Director Robert Redfield warned on Wednesday that the US could see an additional 180,000 coronavirus-related deaths between today and the end of January — an average of at least 3,000 a day.Meanwhile, coronavirus hospitalizations in the US topped 100,000 on Wednesday according to the COVID Tracking Project, a mark that is well above the spring and summer surges of the coronavirus. Nearly 13% of all US hospital beds are being used by coronavirus patients, placing the nation’s health care system in a precarious situation.Despite population increases since the 1970s, the number of hospital beds in America has steadily declined, according to CDC figures.Wednesday's figures would likely not include infections that occurred during the Thanksgiving holiday weekend as coronavirus infections can take weeks to cause hospitalizations. Public health experts are fearful that despite some states implementing shutdowns of businesses, that holiday travel will cause an additional spike in coronavirus cases.According to Johns Hopkins, the U.S. has recorded at least 100,000 new COVID-19 cases each day since Nov. 3. 1472
The US Centers for Disease Control and Prevention continues to warn against eating any romaine lettuce harvested from the central Coastal growing regions of Northern and Central California amid a multistate outbreak of E. coli illnesses linked to romaine lettuce. The agency also reported Thursday that nine additional people have been reported ill since November 26.Now, 52 people have been infected with E. coli in this outbreak, which was announced in October, according to the CDC.Illnesses have been reported in 15 states: California, Connecticut, Florida, Illinois, Louisiana, Massachusetts, Maryland, Michigan, New Hampshire, New Jersey, New York, Ohio, Pennsylvania, Rhode Island and Wisconsin.Nineteen people have been hospitalized, including two who developed hemolytic uremic syndrome, a type of kidney failure. No deaths have been reported.Last month, the CDC and the US Food and Drug Administration updated their warning against eating or selling romaine lettuce products harvested in the California counties of Monterey, San Benito, San Luis Obispo, Santa Barbara, Santa Cruz and Ventura. 1110
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