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WASHINGTON, Nov. 18 (Xinhua) -- The U.S. Food and Drug Administration (FDA) on Friday revoked its approval of Avastin for treating the breast cancer after concluding that the drug has not been shown to be safe and effective for that use.Avastin will still remain on the market as an approved treatment for certain types of colon, lung, kidney and brain cancer."After reviewing the available studies it is clear that women who take Avastin for metastatic breast cancer risk potentially life-threatening side effects without proof that the use of Avastin will provide a benefit, in terms of delay in tumor growth, that would justify those risks," FDA Commissioner Margaret Hamburg said in a statement. "Nor is there evidence that use of Avastin will either help them live longer or improve their quality of life. "Avastin's risks include severe high blood pressure; bleeding and hemorrhaging; heart attack or heart failure; and the development of perforations in different parts of the body such as the nose, stomach, and intestines.Avastin was approved for metastatic breast cancer in February 2008 under the FDA's accelerated approval program, which allows a drug to be approved based on data that are not sufficiently complete to permit full approval. After the approval, the drug's sponsor, Genentech, completed two additional clinical trials and submitted the data from those studies to the FDA. These data showed only a small effect on tumor growth without evidence that patients lived any longer or had a better quality of life compared to taking standard chemotherapy alone -- not enough to outweigh the risk of taking the drug.FDA's Center for Drug Evaluation and Research, which is responsible for the approval of this drug, ultimately concluded that the results of these additional studies did not justify continued approval and notified Genentech it was proposing to withdraw approval of the indication.Genentech did not agree with the Center's evaluation of the data and, following the procedures set out in FDA regulations, requested a hearing on the Center's withdrawal proposal, with a decision to be made by the Commissioner. That two-day hearing, which took place June 28-29, included recommendations from the FDA 's Oncologic Drugs Advisory Committee, voting 6-0 in favor of withdrawing approval of Avastin's breast cancer indication.

SAN FRANCISCO, Dec. 15 (Xinhua) -- Microsoft on Thursday announced that it will automatically upgrade the Internet Explorer (IE) to the latest version to give Windows customers more protection against malicious software.According to the company's blog post, starting from Australia and Brazil next January, users of Windows XP, Vista and Windows 7 will get the IE updates if they have turned on automatic updating via Windows Update.Microsoft said the industry has been moving toward automatic updates as a norm since the biggest online threat these days is social engineering malware typically targeting outdated software like Web browsers.Automatic upgrades, also called silent updates for displaying no messages or windows during the progress, has been deployed by Google's Chrome and Mozilla's Firefox. It can ensure users have the newest versions of the browser, and therefore is seen as a big improvement to Internet security.According to the Microsoft Security Intelligence Report released in October, 99 percent of all attacks during the first half of 2011 came from unpatched but known vulnerabilities, and 90 percent of infections were attributed to vulnerability exploitation that had a security update available from the software vendor for more than a year.In the latest research data from Web analytics company StatCounter, Microsoft's IE has a strong lead with 40.63 percent of global browser market share, followed by 25.7 percent of Chrome and 25.23 percent of Firefox.
HEFEI, Nov. 25 (Xinhua) -- China's leading private automaker, Chery Automobile Co., Ltd., is expected to export a record 170,000 units of vehicles in 2011, marking the highest annual export figure in the company's history, a company manager said Friday.Chery exported 135,556 units of vehicles in the first ten months of this year, up 77.3 percent from a year earlier. This total accounts for 35.3 percent of total passenger vehicle exports of domestic brands, said Feng Ping, deputy general manager of Chery International.The central Anhui province-based carmaker started exporting cars in 2001, when it sold ten cars to Syria, and has since led export sales amongst Chinese automakers.The company exports its products to more than 80 countries and regions, and has established 3 research institutions, a service network of 1,000 dealers and more than 800 service stations overseas.
来源:资阳报