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The US Food and Drug Administration approved a drug to return sexual desire to some women with low libido, the agency said Friday.The drug, bremelanotide, sold under the brand name Vyleesi by AMAG Pharmaceuticals, is an injection to be taken before sex. It's intended to treat women who are premenopausal and have hypoactive sexual desire disorder, where a lack of interest in sex may cause significant distress in a woman's life.It will be available in September, and the company has not yet determined pricing or reimbursement information, according to AMAG spokeswoman Sarah Connors."Most women who come into my office have no idea that there's this condition ... and that they are one of millions," said Sheryl Kingsberg, division chief of Behavioral Medicine at University Hospitals Cleveland Medical Center. Kingsberg was involved in the drug's clinical trials and has served as a paid consultant for the companies responsible for its marketing and development, AMAG and Palatin Technologies.Kingsberg, a clinical psychologist, said that "the impact of sexual dysfunction on a woman's self-esteem, on her body image, on her self-confidence and on her relationship is profound."Experts say the diagnosis is the most common type of sexual dysfunction among women, estimated to affect between 1308

The US Food and Drug Administration announced Wednesday it is investigating a possible connection between e-cigarette use and seizures in younger users.In a public notice the agency reported "a recent uptick in voluntary reports of adverse experiences with tobacco products that mentioned seizures occurring with e-cigarette use (e.g., vaping)" signaling "a potential emerging safety issue."Since June 2018, the FDA said it has "observed a slight but noticeable increase in reports of seizures" connected with e-cigarette use."After examining poison control centers' reports between 2010 and early 2019, the FDA determined that, between the poison control centers and the FDA, there were a total of 35 reported cases of seizures mentioning use of e-cigarettes within that timeframe," the notice says. "Due to the voluntary nature of these case reports, there may be more instances of seizure in e-cigarette users than have been reported."FDA commissioner Dr. Scott Gottlieb released an accompanying statement explaining why the agency was releasing the information."We want to be clear that we don't yet know if there's a direct relationship between the use of e-cigarettes and a risk of seizure. We can't yet say for certain that e-cigarettes are causing these seizures," he said."We're sharing this early information with the public because as a public health agency, it's our job to communicate about potential safety concerns associated with the products we regulate that are under scientific investigation by the agency. This also helps encourage the public to voluntarily report additional adverse events that can better inform our work." 1656

The Supreme Court agreed on Friday to take up an abortion case this term, adding an explosive issue to an already robust docket of controversial issues in the middle of the 2020 presidential election.The justices will consider a Louisiana law that requires doctors to obtain admitting privileges from a nearby hospital.This is the first abortion case that will be argued since Justice Brett Kavanaugh and Neil Gorsuch joined the bench, solidifying a conservative majority.While the case does not directly challenge Roe v Wade, supporters of abortion rights are fearful that this is the first of what could be a growing number of opportunities for the new conservative majority to chip away at abortion rights.A Supreme Court ruling on abortion could play a massive role in shaping the presidential race.President Donald Trump and Republicans seeking to hold onto their Senate majority for years have rallied their evangelical base -- including those who might find Trump's personal behavior distasteful -- around the promise of a right-leaning court that could lock in conservative victories for years to come. A court ruling that chips away at abortion rights, with more opportunities for the court to take up abortion in the near future, would galvanize that base.The case is one of several cultural touchstones the Supreme Court will take up this year -- including cases on employment discrimination against LGBT Americans, gun rights, and Trump's elimination of protections undocumented immigrants brought into the United States as children. In recent years, polls have shown majorities of voters aligning with Democrats on those issues, particularly in the formerly Republican but rapidly shifting suburbs. If the court scales back on abortion rights and undercuts Obama-era steps on other key issues, those cultural issues could move to the forefront of the election.Louisiana lawThe Louisiana law, which has been 1932

The State Department told CNN on Saturday that the United States is cutting off aid to the Northern Triangle, as the territory made up of the Central American countries of El Salvador, Guatemala and Honduras is known, after President Donald Trump said this Friday that they had "established" caravans of migrants to enter the United States."We were paying them huge amounts of money. And we are not paying them anymore. Because they have not done anything for us. They installed these caravans, "said Trump. "Following the secretary's instructions, we are conducting the president's address and ending the foreign assistance programs for the Northern Triangle for fiscal year 2017 and fiscal year 2018," said a spokesman for the State Department. "We will participate in the Congress as part of this process."Trump threatened to interrupt or substantially reduce aid to the Northern Triangle before saying in an October tweet that countries "could not do the job of arresting people since they left their country and came to the United States illegally." But experts have said that cutting aid will likely increase the number of migrants leaving countries and heading to the United States."Cutting aid could worsen the circumstances for families fleeing violence and conflict. The American aid associations in these places are working to address the root causes of violence in Honduras, Guatemala and El Salvador. This is a time when these countries could use additional investments and partnerships from the United States to promote economic opportunities and security for their citizens, nothing less, "said the United States Global Leadership Coalition, composed of retired diplomats, military leaders and members of Congress. As for the possibility, the help could be cut. The officials did not say exactly how much money would be affected by the directive and it is likely that part of the amount has already been spent. According to a study by the Congressional Research Service, between last year and this year, about 1,300 million dollars were allocated to the region, and the great majority went to those three countries. 2142

The University of Missouri-Kansas City has filed a lawsuit against a former professor, alleging that he stole and sold his graduate student's research for .5 million.The suit, filed this week, says Ashim Mitra swiped a "groundbreaking" drug formulation from the student and stands to gain as much as million more in royalties.Mitra, who has resigned from the university, denied the allegations to CNN.Also named in the lawsuit are Mitra's wife, who worked in her husband's lab, and two pharmaceutical companies that used the invention.The university alleges Mitra worked in secret with the companies to develop the patent, which outlines an innovative way of delivering drugs to the eye using nanotechnologyThe pharmaceutical product has recently received FDA approval, the university said. It's a treatment for dry eye, an ailment common to the elderly.The university's contentionIn a statement to CNN, the university said:"Mitra stole UMKC-owned inventions, sold them to industry, assisted those companies in patenting and commercializing them, denied credit to a deserving student and reaped a personal financial windfall -- all the while concealing his efforts and denying his involvement."The lawsuit seeks to designate the student, Kishore Cholkar, as the rightful inventor to the patent based on his research from 2010.The university policy is that it owns the rights to discoveries made by staff and students while they are working at the university. When commercial rewards are reaped, the inventor is entitled to one-third of the profits and the school keeps the remaining two-thirds, the school said.The professor's reactionReached by phone Thursday, the professor denied the allegations and told CNN that Cholkar doesn't deserve credit for the patent."Everyone is trying to jump in and get a piece of the pie," he said.He said he conceived of the formulation with the drug companies through his private consultancy business, adding that "the student arrived after the patent was signed."Cholkar's work involved a part of the eye not affected by the drug, Mitra said.He added that he's consulting with his lawyers on how best to tackle the lawsuit.Cholkar, the student, now works at a California-based pharmaceutical company. CNN has reached out to Cholkar for comment. 2298

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