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GENEVA — The U.N. health agency says the world’s largest randomized trial of COVID-19 treatments found “conclusive evidence” that remdesivir, a drug used to treat U.S. President Donald Trump when he fell ill, has little or no effect on severe cases. The World Health Organization has announced long-awaited results of its six-month “Solidarity Therapeutics Trial” that endeavored to see if existing drugs might have an effect on the coronavirus. The study, which was not peer-reviewed, found that four treatments tested — remdesivir, hydroxychloroquine, lopinavir/ritonavir and interferon — had “ little or no effect on 28-day mortality or the in-hospital course of COVID-19 among hospitalized patients.” Remdesivir was the only drug of the four that had not largely been ruled out as ineffective in fighting COVID-19. 826

HOLLYWOOD, Calif. (CNS) - Another prominent filmmaker was accused Wednesday of extensive sexual misconduct.In interviews with the Los Angeles Times, actress Natasha Henstridge and five other women accused director and producer Brett Ratner of a range of sexual harassment and misconduct in private homes, on movie sets or at industry events.Ratner, through his lawyer, denied all the allegations, which included forcing women to perform sex acts and pleasuring himself in front of them."I have represented Mr. Ratner for two decades, and no woman has ever made a claim against him for sexual misconduct or sexual harassment," Singer said in a 10-page letter to The Times. "Furthermore, no woman has ever requested or received any financial settlement from my client."Ratner has become one of Hollywood's most powerful players, directing, producing or financing dozens of today's biggest box-office hits, including "Rush Hour," "X-Men: The Last Stand," "The Revenant" and "Horrible Bosses," according to The Times.Now 48, Ratner has long flaunted his playboy persona, bragging publicly about his sexual prowess, according to The Times. He has been romantically linked to Paris Hilton, Lindsay Lohan and Mariah Carey.The women quoted by The Times today are actresses Natasha Henstridge, Olivia Munn, Jaime Ray Newman,  Katharine Towne, aspiring singer Eri Sasaki and background actress Jorina King.As hundreds of women have come forward in recent weeks with allegations of sexual misconduct at the hands of producer Harvey Weinstein, director James Toback and other powerful men, Henstridge decided she would no longer remain silent, The Times reported. As is often the case, none of the allegations, which date back to the early 1990s, were reported to  police.The Beverly Hills Police Department, meanwhile, is investigating "multiple complaints" involving Weinstein and James Toback, two longtime film industry figures who have each been the subject of numerous accusations of sexual harassment and sexual assault."The Beverly Hills Police Department has recently received multiple complaints involving Harvey Weinstein. These cases are under investigation and no further information will be released at this time," police said in a statement. The department sent an identical release involving Toback, a writer and director. Weinstein, a producer long considered one of Hollywood's most powerful people, was fired from The Weinstein Company after dozens of women accused him of sexual harassment or assault. He was also expelled from the Academy of Motion Picture Arts and Sciences, the Producers' Guild. and the Directors' Guild is expected to follow suit, having initiated the process.Weinstein has apologized for his behavior but vehemently denied ever engaging in non-consensual sexual activity. The Los Angeles Police Department has announced it is investigating a sexual assault allegation against Weinstein. That allegation was made by an Italian model-actress who claims Weinstein raped her in 2013 at a hotel while she was in town for an Italian film festival.Police in New York and London have said they are investigating allegations of sexual assault involving Weinstein as well.As for Toback, 38 women recently emerged to report years of perverted and creepy behavior by the director whose credits include "The Pick-up Artist" and "Black & White." The Los Angeles Times reported that it spoke to the women about the allegations, with 31 speaking on the record. 3501

HONG KONG – Scientists at the University of Hong Kong claim to have the first evidence of someone being reinfected with the coronavirus that causes COVID-19.They said Monday that genetic tests show a 33-year-old man returning to Hong Kong from a trip to Spain in mid-August had a different strain of the virus than the one he’d previously been infected with in March.The man had mild symptoms the first time and none the second time, so his previous infection may have helped prevent serious illness.Experts say waning immunity could have implications for vaccine development and that the case shows the need to keep up social distancing and other prevention measures.Dr. Kelvin Kai-Wang To, who led the group of scientists, told The Associated Press that it’s unknown how many people can get reinfected, but there are probably more out there.Even if someone can be infected a second time, it’s not known if they have some protection against serious illness, because the immune system generally remembers how to make antibodies against a virus it’s seen before. 1069

Gyms are doing whatever they can to get you back, but many are wondering if it’s safe. A public health expert says it depends on what precautions your gym is taking.“The fact is that the gyms don't spread disease,” said Dr. Jay Wolfson, a public health professor at the University of South Florida. “The people within them who are coming into the gym and not cleaning up after themselves and are not maintaining social distances, and the gym staff, if they're not being attentive and conscientious in terms of disinfecting, are the ones who are aiding a abetting the spread of the disease.”There's evidence showing coronavirus can be spread through aerosol and droplets. Those droplets can float in the air long enough to be inhaled. And they could travel more aggressively when we’re working out.“Just as when you yell and scream, and you'll be sweating, and you'll be hyperventilating sometimes, so those droplet nuclei are going to come out, which means the larger particles are going to rest on some of the equipment as well as in the air,” said Wolfson.Wolfson says it may be hard to monitor gyms across the country because the rules in certain cities and states are different. And it's hard to know if a case is tied to a gym.A Norwegian university looked at whether workout facilities played a role in the spread. It didn't find any cases in people who went to the gym and took proper precautions.Researchers said going to the gym is relatively safe in areas where there aren't many infections. 1509

George Papadopoulos, the former Trump campaign adviser who pleaded guilty to lying to the FBI, is making his first appearance testifying on Capitol Hill later this month.Papadopoulos is expected to testify behind closed doors before a small group of lawmakers on the House Judiciary and Oversight committees on October 25, according to two sources familiar with the matter.The interview is part of Judiciary Chairman Bob Goodlatte and Oversight Chairman Trey Gowdy's investigation into the FBI's handling of the Hillary Clinton email and Russia investigations, although Democrats are likely to press the former Trump foreign policy adviser on potential Russia collusion, too.Papadopoulos has also been in discussions with the Senate Intelligence Committee for an interview, according to one of the sources. And California Rep. Adam Schiff, the top Democrat on the House Intelligence Committee, has expressed a desire to speak to Papadopoulos as part of his investigation into potential collusion between Trump's team and Russia. Schiff and the House Intelligence Committee Democrats interviewed Papadopoulos' wife, Simona Mangiante Papadopoulos, in July.A committee aide said the panel's Democrats are still interested in talking to Papadopoulos and "look forward to scheduling an interview at the appropriate time."Papadopoulos tweeted?Thursday that he was coming to Capitol Hill, suggesting there was an effort to discredit him and his wife before he testified and denying any involvement with Russian collusion."The attempt to discredit my wife and I before my testimony on capitol hill has reached a fever pitch," he tweeted. "Someone is nervous. I think America was smart enough to realize that someone who has never knowingly met a Russian official in their life never could have colluded. Fake news."Papadopoulos pleaded guilty last year to lying to the FBI over his contacts with individuals tied to Russia during the 2016 campaign. He lied about his interactions with Maltese professor Joseph Mifsud, who told Papadopoulos that the Russians had "thousands of emails" about Clinton, according to the charging documents from special counsel Robert Mueller.Papadopoulos told CNN's Jake Tapper last month that he did not recall sharing the information from Mifsud with anyone on the Trump campaign, though he did not completely shut the door on the possibility. "As far as I remember, I absolutely did not share this information with anyone on the campaign," Papadopoulos said, adding, "I might have, but I have no recollection of doing so. I can't guarantee. All I can say is, my memory is telling me that I never shared it with anyone on the campaign."He was sentenced in September?to two weeks in prison, which he has not yet served.Since the sentence, Papadopoulos has suggested on Twitter that British intelligence officials were behind his meeting with Mifsud.A lawyer for Papadopoulos did not respond to a request for comment. 2961