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LOS ANGELES (CNS) - USC researchers have found the likely order in which COVID-19 symptoms first appear: fever, then cough and muscle pain, followed by nausea, and/or vomiting, and diarrhea, it was announced Thursday.Knowing the order of COVID-19's symptoms may help patients seek care promptly or decide sooner than later to self isolate, according to scientists at the USC Michelson Center for Convergent Bioscience. The information also may help doctors rule out other illnesses, or help doctors plan how to treat patients, and perhaps intervene earlier in the disease.The study, which appears in the journal Frontiers in Public Health, was led by doctoral candidate Joseph Larsen and scientists Peter Kuhn and James Hicks at the USC Michelson Center's Convergent Science Institute in Cancer."This order is especially important to know when we have overlapping cycles of illnesses like the flu that coincide with infections of COVID-19," said Kuhn, a USC professor of medicine, biomedical engineering, and aerospace and mechanical engineering. "Doctors can determine what steps to take to care for the patient, and they may prevent the patient's condition from worsening."Fever and cough are frequently associated with a variety of respiratory illnesses, including influenza, Middle East Respiratory Syndrome and Severe Acute Respiratory Syndrome. But the timing and symptoms in the upper and lower gastrointestinal tract set COVID-19 apart."Given that there are now better approaches to treatments for COVID- 19, identifying patients earlier could reduce hospitalization time," Larsen said.To determine COVID symptom chronology, the authors analyzed more than 55,000 confirmed coronavirus cases in China collected from Feb. 16 to Feb. 24 by the World Health Organization. They also studied a dataset of nearly 1,100 cases collected from Dec. 11 through Jan. 29 by the China Medical Treatment Expert Group via the National Health Commission of China.In addition, to compare the order of COVID-19 symptoms to influenza, the researchers examined data from 2,470 cases in North America, Europe and the Southern Hemisphere, which were reported to health authorities from 1994 to 1998."The order of the symptoms matter, " Larsen said. "Knowing that each illness progresses differently means that doctors can identify sooner whether someone likely has COVID-19, or another illness, which can help them make better treatment decisions." 2440

LONG BEACH, Calif. (KGTV) - A man with a handgun prompted a standoff with police near Long Beach City Hall Wednesday.A "hysterical female" called 911 to reported her husband was armed at a federal building, according to ABC affiliate KABC. Los Angeles Sheriff's Department deputies and Long Beach Police responded to the suspect in the 300 block of Ocean Blvd. just before 4 p.m., where the standoff began.LASD said the suspect had a "possible improvised explosive device" in his vehicle.SWAT officers and bomb squad officers were at the scene as the man has stood outside a van with his arms raised. He appeared to have a gun in his hand, according to officers.The standoff ended at about 6 p.m. after a police K-9 brought the man down.Long Beach Mayor Robert Garcia tweeted that police had escorted employees out of City Hall and that "everyone is safe." 874

LOS ANGELES (AP) — Authorities say a Los Angeles County sheriff's deputy who said he was shot in a station parking lot was lying.Assistant Sheriff Robin Limon said at a news conference late Saturday that Wednesday's "reported sniper assault was fabricated" by Angel Reinosa, a 21-year-old deputy.A department statement on Thursday had said a round hit the top of Reinosa's shoulder, damaging his uniform shirt but failing to penetrate his flesh.But Sheriff's Capt. Kent Wegener says no bullets were recovered from the scene and detectives saw "no visible injuries." He says Reinosa eventually admitted making up the story and using a knife to cut the two holes in his shirt.Reinosa has been relieved of his duties and will face a criminal investigation. Wegener says Reinosa didn't explain a motive. 807

LONDON (AP) — Authorities say a Florida teen hacked the Twitter accounts of prominent politicians, celebrities and technology moguls to scam people around the globe out of more than 0,000 in Bitcoin. The 17-year-old boy was arrested Friday in Tampa. He faces 30 felony charges.“These crimes were perpetrated using the names of famous people and celebrities, but they’re not the primary victims here. This ‘Bit-Con’ was designed to steal money from regular Americans from all over the country, including here in Florida. This massive fraud was orchestrated right here in our backyard, and we will not stand for that,” Hillsborough State Attorney Andrew Warren said.The hacks led to bogus tweets being sent out July 15 from the accounts of Barack Obama, Joe Biden, Mike Bloomberg, and a number of tech billionaires including Amazon CEO Jeff Bezos, Microsoft co-founder Bill Gates and Tesla CEO Elon Musk. The tweets offered to send ,000 for every ,000 sent to an anonymous Bitcoin address.“I want to congratulate our federal law enforcement partners—the US Attorney’s Office for the Northern District of California, the FBI, the IRS, and the Secret Service—as well as the Florida Department of Law enforcement. They worked quickly to investigate and identify the perpetrator of a sophisticated and extensive fraud,” State Attorney Warren said.“This defendant lives here in Tampa, he committed the crime here, and he’ll be prosecuted here,” Warren added.The FBI and the U.S. Department of Justice conducted a complex nationwide investigation and located the teen in Hillsborough County.The teen is facing the following charges:Organized fraud of over ,00017 counts of communications fraud of over 0Fraudulent use of personal information of over 0,000 or 30 or more victims10 counts of fraudulent use of personal informationAccess to computer or electronic device without authority, scheme to defraud“Working together, we will hold this defendant accountable,” Warren said. “Scamming people out of their hard-earned money is always wrong. Whether you’re taking advantage of someone in person or on the internet, trying to steal their cash or their cryptocurrency—it’s fraud, it’s illegal, and you won’t get away with it.” 2241

LOS ANGELES (AP) — Officials have vowed to find what sparked the inferno aboard the dive boat Conception that killed 34 people in waters off Southern California, but vital evidence may have gone down with the ship or drifted out to sea.The main piece of evidence, the charred remains of the boat, rests on the sea floor in 60 feet (18 meters) of water. Other items that could provide valuable clues could have been carried away by tides or destroyed in the blaze that burned so hot DNA is needed to identify the dead."All of that will be a very large hurdle to overcome," said George Zeitler, a former Coast Guard inspector who runs his own marine investigation firm. "It will definitely make for a complex investigation."Investigators will want to craft a timeline of the ship's final voyage from the moment it pulled away from a Santa Barbara dock early Saturday morning until dispatchers received the frantic mayday call of the breathless captain overwhelmed by smoke, experts said.RELATED: San Diego woman killed in deadly Conception boat fire off Santa BarbaraThey will look at the ship's layout and whether the bunk room below deck was too cramped and had enough exits, review maintenance records and even study photos and videos from people who have been on the boat to look for valuable evidence.As the investigation into the Labor Day tragedy expands on land and sea, federal and local authorities will look not only at determining what went wrong but also seek lessons that could lead to changes in commercial vessel regulations."Our mission here while we're on scene is to determine how this happened, why it happened and what safety improvements are needed to prevent it from ever happening again," said Jennifer Homendy of the National Transportation Safety Board.The fire, investigated with help from the FBI and Bureau of Alcohol, Tobacco, Firearms and Explosives, is being treated as an accident and there's nothing to suggest anything "nefarious," said Santa Barbara County Sheriff Lt. Erik Raney.The Conception, owned by Truth Aquatics, had been chartered for three days by a commercial dive outfit based in Santa Cruz to explore the rugged Channel Islands, sometimes referred to as the Galapagos of North America, about 20 miles (32 kilometers) south of Santa Barbara.The mayday call came at 3:15 a.m. Monday as passengers would have been sleeping while the boat was anchored just off Santa Cruz Island.While initial details were limited, Santa Barbara County Sheriff Bill Brown said fire above deck blocked the one stairway and an emergency exit hatch where 33 passengers and one crew member were sleeping in their bunks. It's not known if any alarm sounded or what the people below deck may have done to try to escape."If an emergency exit is blocked due to fire and prevents one from escaping, it's a horrific situation," said Hendrik Keijer, an investigator with Robson Forensic who has captained cruise ships and operated cargo boats. "Vessels are mazes."The five survivors were all crew members, including the captain. They apparently jumped from the boat's bow, where the stairway led to the sleeping quarters, and swam to the stern, where they escaped in a dinghy and were taken aboard a nearby boat.Attorney James Mercante, a former merchant marine officer who has defended thousands of maritime casualty cases, said it was unusual that only crew members survived, but that is likely because they were above deck.Mercante said he would want to find out what the crew did upon being alerted to fight the fire and for how long before they abandoned ship."Something was ignited that spread a fire rapidly," Mercante said. "It must have spread awfully quickly if nobody but the crew got out."Even with limited physical evidence, fire investigators should be able to pinpoint where the fire began, though finding the cause will be more difficult, Mercante said.The leading causes of boat fires are, specifically, electrical problems and, generally, stupidity, said Walter Godfrey, who has investigated more than 2,000 boat fires in a career spanning a half-century.By all accounts Godfrey has seen, Truth Aquatics had a good reputation and a clean record of service and was not the type of outfit to employ do-it-yourself electrical wiring."I don't think they'd be cutting those kind of corners," Godfrey said. "I would think just off the top of the head this would have to have been something totally accidental and not something ... you would anticipate."Coast Guard records show fire safety violations on the Conception in 2014 and 2016 were quickly fixed. There were no deficiencies found in February or August 2018 inspections.The same problems that lead to house fires every day can also sink ships: kitchen fires, unextinguished cigarette butts and gas leaks.While experts did not want to speculate on a cause, Godfrey said he would want to know more about the built-in barbecue on board and where gasoline was stored for the dinghy. He said electrical fires are most common because a boat — even when docked — is always moving and wires get chafed and exposed. They can arc and spark or ignite gas vapors.A fire on board can rapidly become a terrifying situation with no help nearby."It's very difficult to fight fires without outside help," Keijer said. "You're really on your own in most instances. It's up to the vessel's crew to fight fires. It's not like one can easily escape a vessel. You walk out of a building if a fire occurs on land. That's not as easy on vessels." 5515

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