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SAN DIEGO (KGTV) — UC San Diego Health and three other UC Health medical centers will begin to recruit participants for an antiviral drug being tested to treat the novel coronavirus.The medical system will start "phase II" clinical trials for the antiviral drug remdesivir. The drug has "shown activity in animal models and human clinical trials of SARS-CoV, MERS-CoV, Ebola, Marburg and other viruses," according to UCSD Health.RELATED: San Diego hospitals start drives for personal protective equipmentRemdesivir is not currently approved for the treatment of any infection by the FDA, but is currently undergoing trials for treating multiple viruses, including COVID-19.“With this type of adaptive study design, if remdesivir proves to be safe and active, the clinical trial may be rapidly adapted to remove the requirement for a placebo arm and add a treatment arm that includes other promising antiviral or other investigational drug to compare with the activity of remdesivir," said co-principal investigator Constance Benson, professor of medicine at UC San Diego School of Medicine and an infectious disease specialist at UC San Diego Health.RELATED: Nurse urges people to turn over N95 masks to San Diego hospitalsUC San Francisco, UC Irvine Health, and UC Davis Health are also participating in the trials. The trial is projected to run until April 1, 2023 and involve 440 participants. 1404

SAN DIEGO (KGTV) — UC San Diego says it plans to begin repopulating its campus this summer, with about 30% of courses being held in person this fall.The campus says in-person classes will be limited to less than 50 students per class or 50% classroom capacity, whichever is lower. Any classes with more than 50 students enrolled will be offered remotely.Some classes will also be held in a hybrid format. The fall quarter is set to begin on Sept. 28, with student arrivals to campus being staggered to protect the capacity for testing."We aim to mitigate risk in a way that will allow UC San Diego to provide an environment for learning and offer a university experience that our students expect," said Chancellor Pradeep Khosla. "As one of the nation’s leading research universities, we have risen to meet difficult circumstances and responded with innovation every step of the way."For students attending in-person classes, facial coverings will be required, according to the school. Students will also be tested for COVID-19 monthly and when moving in on campus.UCSD plans to offer regular coronavirus testing to students, faculty, and staff, with higher frequency in testing for those who are at higher risk for infection. The campus says there will be no cost for asymptomatic or symptomatic testing for students, faculty, and staff when done at a UC San Diego Health location or through Student Health Services.“Our adaptive model considers the most current science on transmission and infection risk and will drive our determinations on the testing frequency of our various campus populations,” said project lead Natasha Martin, associate professor of medicine at UC San Diego School of Medicine. “We wanted a simple, easy testing process which can be delivered at scale in the fall to ensure widespread testing for early outbreak detection.“Our simulations indicate that if more than 75 percent of the population were tested per month, we would be able to detect an outbreak before there are 10 detectable infections on campus,” she said.Students aren't thrilled at the impact the coronavirus is having on their college experience."You can't really make new friends and meet new people and do many projects strictly online," Dylan Nelson said. He will be an incoming Junior at UC San Diego. This summer his internship in New York was also put on hold due to the pandemic, but he's finding the silver lining."Fortunately all [my classes are] computer based classes, so a lot of that was going to be online anyway so it's not too hard to adapt," adding, "as a Junior I think it's tough but not the worst, I feel bad for all the Seniors going in right now because you're missing out on potentially really big classes."ABC 10News asked if he would feel comfortable returning to class wearing a face covering, "for me personally no, I think for other people in certain classes they might want the more in person aspect."Nelson is hopeful for the future, saying this to his fellow Tritons, "hang in there and stay safe or this may be even longer than we want it to be." 3079

SAN DIEGO (KGTV) — UC San Diego says it plans to begin repopulating its campus this summer, with about 30% of courses being held in person this fall.The campus says in-person classes will be limited to less than 50 students per class or 50% classroom capacity, whichever is lower. Any classes with more than 50 students enrolled will be offered remotely.Some classes will also be held in a hybrid format. The fall quarter is set to begin on Sept. 28, with student arrivals to campus being staggered to protect the capacity for testing."We aim to mitigate risk in a way that will allow UC San Diego to provide an environment for learning and offer a university experience that our students expect," said Chancellor Pradeep Khosla. "As one of the nation’s leading research universities, we have risen to meet difficult circumstances and responded with innovation every step of the way."For students attending in-person classes, facial coverings will be required, according to the school. Students will also be tested for COVID-19 monthly and when moving in on campus.UCSD plans to offer regular coronavirus testing to students, faculty, and staff, with higher frequency in testing for those who are at higher risk for infection. The campus says there will be no cost for asymptomatic or symptomatic testing for students, faculty, and staff when done at a UC San Diego Health location or through Student Health Services.“Our adaptive model considers the most current science on transmission and infection risk and will drive our determinations on the testing frequency of our various campus populations,” said project lead Natasha Martin, associate professor of medicine at UC San Diego School of Medicine. “We wanted a simple, easy testing process which can be delivered at scale in the fall to ensure widespread testing for early outbreak detection.“Our simulations indicate that if more than 75 percent of the population were tested per month, we would be able to detect an outbreak before there are 10 detectable infections on campus,” she said.Students aren't thrilled at the impact the coronavirus is having on their college experience."You can't really make new friends and meet new people and do many projects strictly online," Dylan Nelson said. He will be an incoming Junior at UC San Diego. This summer his internship in New York was also put on hold due to the pandemic, but he's finding the silver lining."Fortunately all [my classes are] computer based classes, so a lot of that was going to be online anyway so it's not too hard to adapt," adding, "as a Junior I think it's tough but not the worst, I feel bad for all the Seniors going in right now because you're missing out on potentially really big classes."ABC 10News asked if he would feel comfortable returning to class wearing a face covering, "for me personally no, I think for other people in certain classes they might want the more in person aspect."Nelson is hopeful for the future, saying this to his fellow Tritons, "hang in there and stay safe or this may be even longer than we want it to be." 3079

SAN DIEGO (KGTV) - When a baby is born premature, a family’s world can be turned upside down. November is Prematurity Awareness Month. So, in recognition of that, the March of Dimes donated 50 care packages filled with everything from fuzzy socks to crossword puzzles, and tissues to parents who spend countless hours with their babies in the NICU. "Oh, is that funny?" says mom Vanessa holding her newborn. For a mother, anything her newborn does is a little miracle. "So this is our boy Ezekial,” says Vanessa showing off her little miracle. “He was 3 pounds, 10 ounces." But Ezekial is only one of three miracles. There's also sister Eleana, and little Evelyn. Triplets, three little miracles, born nine weeks premature at Sharp Mary Birch. "I spent three and a half weeks upstairs on the fourth floor, admitted. Um, it was hard,” adds Vanessa holding back tears. “I carried the triplets until 31 weeks and three days, and we've been here ever since, I'm going on about 40 days." Forty days and counting in the Neonatal Intensive Care Unit at Sharp Mary Birch Hospital. And Vanessa, with a two year old at home already, is here six to nine hours a day. "I come between 10 and 11, and I'll leave about 5 or 6. It just depends. Sometimes it's just hard to leave," says Vanessa. On this day, the March of Dimes is here delivering care packages. A little comfort for parents trying to navigate the emotional roller coaster of life in the NICU. "It's great, the nurses love our babies, and the doctors are amazing,” says Vanessa. “It's just some days are hard because this is what you come to every day. And every day I just want to hear, 'Your babies are ready to go home.'" That day will come, just like it did for Kristina and Mia. "She was born on July 31st, and she was supposed to be born on November 3rd. She was born 1 pound and 9 ounces," says mother Kristina holding her little Mia tight. Mia was 14 weeks premature. "This kind of puts it into perspective of how small she was,” says Kristina showing a picture on her phone. “That's my husband’s finger, and that's her little hand. Her fingers don't even wrap around the tip of his finger." The difficulty of having to leave your baby in the hospital, and the trust that a parent has to have in the nurses who care for them is overwhelming and at the same time, very comforting. “Yes, it is extremely overwhelming, depressing,” says Kristina. “But you bond with these people here and they become family, they really do. That's why I’m back here today to visit my primary nurse. We will always be grateful for everything they did for us here." Mia was part of a March of Dimes study when she was in the NICU at Sharp Mary Birch. Each year more than 22 thousand babies never make it out of the NICU because of complications with premature birth. The awareness and research by the March of Dimes is determined to put an end to that.You can join the March of Dimes effort to help mothers and children at the March for Babies. Learn more here. 3004

SAN DIEGO (KGTV) - Typically dry and brown swaths of San Diego County are currently lush and green due to record-setting levels of rain, indicating the availability of more vegetation with the potential to fuel a wildfire during drier years. To watch for the threat from growing brush and grass, Cal Fire and other agencies track fuel moisture, the amount of water in a plant. When fuel moisture is high, fires do not ignite quickly - or at all, according to the National Oceanographic and Atmospheric Association. Fires spark easily and spread fast when fuel moisture is low. Any fuel moisture content level below 30 percent indicates the brush is dead and at the mercy of temperatures, humidity and winds, NOAA reports. The calculations are critical for firefighters when Santa Ana conditions arrive and San Diego’s winter storms are a distant memory. “A direct relationship to this rain is how damp that brush is throughout the summer, or how high it is,” said Cal Fire Captain Jon Heggie. “Think of it as a sponge and it’s full of water right now,” said Heggie. “We’ll monitor that throughout the year and as we get closer to the heat of the summer we’ll really pay attention to what those levels are. Once they hit certain thresholds, that’s when we know fire danger is really at its highest.” Fuels were critically dry before San Diego County’s Cedar Fire in 2003, the U.S. Forest Service and California Department of Forestry reported. Humidity levels monitored at the Descanso Fire Station dropped to 4 percent, with the fire moisture level of the brush plunging to the same low. To make the situation worse, the county had experienced several years of below-normal rainfall. Although chaparral and coastal scrub were the most likely to burn in the Cedar Fire, Heggie called grass a “huge contributor” to fire growth in California. Heggie’s assertion echoes what climate change scientists from Scripps Institution of Oceanography, San Diego State University and other local research outlets discovered about fire fuel. “One climactic variable that has become important in recent years is high prior-year precipitation, likely due to its role in promoting higher abundance of annual grasses that, once dry, become extremely ignition prone in the subsequent year,” the group wrote in a study about the ecological impacts of climate change. Heggie, who has been fighting fires in San Diego County for 25 years, has noticed the changing weather patterns. “I’ve seen conditions gradually get worse for probably the last decade; what that tells me is that the landscape is reacting to those ten years of drought.” To alleviate the threat, fire agencies routinely conduct brush mitigation activities including controlled burns and, on occasion, using goats to eat through unwieldy vegetation. “There’s so much fuel, we are doing our best to stay in front of it, but the tremendous amount of fuel on the landscape is going to take decades for us to really get a handle on,” said Heggie. Cal Fire increased the amount of controlled burns planned for 2019, but Heggie says preventing fire is key. He encourages San Diegans to clear the brush around their homes and be careful on high fire danger days. “Our new normal is that we always have potential for that large fire to break out anyplace here in San Diego County.” 3325

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