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A company that claims to have the first drug to slow mental decline from Alzheimer’s disease made its case to scientists Thursday but left them sharply divided over whether there’s enough evidence of effectiveness for the medicine to warrant federal approval.Excitement and skepticism have surrounded aducanumab since its developers stopped two studies earlier this year because it didn’t seem to be working, then did a stunning about-face in October and said new results suggest it was effective at a high dose.During Thursday’s presentation at an Alzheimer’s 573

A federal judge will sentence Paul Manafort on Thursday for defrauding banks and the government and failing to pay taxes on millions of dollars in income he earned from Ukrainian political consulting -- charges that stemmed from special counsel Robert Mueller's investigation into Russian interference in the 2016 presidential election.The penalty may be steep enough to keep the longtime lobbyist and former Trump campaign chairman in prison for the rest of his life.Prosecutors say that Manafort, 69, deserves between 19 and 25 years in prison as well as millions of dollars in fines and restitution for the crimes, for which a jury convicted him after a three-week trial last summer. Manafort has shown little remorse, they say, and even lied under oath following a plea deal after the trial."The defendant blames everyone from the special counsel's office to his Ukrainian clients for his own criminal choices," prosecutors wrote in a final court filing this week to Judge T.S. Ellis in Alexandria, Virginia.In many ways, the Manafort case -- which reached back almost a decade to track the movement of money from his Ukrainian political consulting work, through the time he was broke and working for Trump in 2016 -- has shaped Mueller's actions for almost two years.Manafort's was the first indictment Mueller announced in late 2017 and it used the criminal prosecution to ratchet up pressure on him throughout 2018 as they sought his cooperation on matters central to their probe. At one point, after securing Manafort's longtime deputy Rick Gates as a witness against him, prosecutors split his case in two, putting the more clear-cut financial crimes indictment in the fast-moving Northern Virginia federal court. Manafort's conviction at trial was a major win for Mueller -- the only official certification from an impartial group of citizens that Mueller had uncovered major crime.The eight crimes for which Manafort will be sentenced on Thursday include five convictions of tax fraud from 2010 through 2014, hiding his foreign bank accounts from federal authorities in 2012 and defrauding two banks for more than million in loans intended for real estate. At his trial, one juror refused to join the other 11 to convict him on 10 additional foreign banking and bank fraud charges. Prosecutors later dropped those counts.Manafort did not testify in his own defense at his trial, which 2411

When it comes to mental health, it's important to have help in an emergency. But what about a place to go before it reaches that level? “People may not even know what the problem is but they know that something isn’t quite right so if they call a ‘warmline’ they're going to get somebody on the other end who is nonjudgmental who will listen to them in a way that maybe family or friends aren’t able to,” says Tom Hill with the National Council for Behavioral Health. So what is a "warmline”? Think of it as a pre-crisis call if you're having a problem or just feeling off. Some people may find themselves feeling especially off amid the holiday season. Someone on the other end of the line can provide emotional support. They can also connect you to a peer coach or support group, a mental health agency or general resources that can help with everyday life. Warmlines are helpful for those living in rural areas. Sometimes, it can be someone's first contact with mental health services. “Warmlines lift barriers and there still exists a lot of barriers for people talking about problems that they're having that they keep to themselves,” Hill says. “And if we keep it to ourselves, we don’t get better.” More than 30 states have their own warmlines.Several of those can also take calls from anywhere in the country.An unofficial list of warmlines by state can be found on 1387

A former East Pittsburgh police officer charged in the shooting death of 17-year-old Antwon Rose II will begin his trial on Tuesday.The killing of the unarmed black teenager last year triggered protests and outrage in Pittsburgh over the officer's use of deadly force. The former officer, Michael Rosfeld, 30, faces a criminal homicide charge, which includes murder, voluntary manslaughter and involuntary manslaughter under Pennsylvania law.The jury has been selected from Dauphin County, which is about 200 miles from Pittsburgh, after a ruling that the publicity around the case had affected the jury pool in Allegheny County. The trial will take place in Pittsburgh with the jurors from the other county.The jury in this racially charged case is predominantly white and older, with two jurors under age 40 and three black jurors, 846

A Connecticut man suffering from cystic fibrosis received a call from his idol, President Donald Trump on Tuesday evening, thanks to his sister — a Democratic politician.According to the 199

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