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A team at the University of Kentucky is researching a possible treatment for COVID-19 and key helpers are three alpacas; Big Boy, Blue Eyes and Emperor.“It’s a powerful technology that we have at UK (University of Kentucky) and it’s something that hopefully we can develop some therapeutics with,” said Wally Whiteheart, a professor in the Department of Molecular & Cellular Biochemistry.Alpacas, along with llamas and camels, make a special kind of antibody called a nanobody. Nanobodies can be useful in cancer research and for other diseases. Researchers, led by Whiteheart and fellow professor Lou Hersh, are working with a nearby ranch to see what impact alpacas could have on COVID-19.“We, in a sense vaccinate them, and this case with viral proteins, and we make nanobodies to those viral proteins,” explained Whiteheart. “We can then go and purify and identify the nanobodies that bind to the virus and then test them to see if they can inhibit viral infection.”Making the nanobodies is just the first step. The team will see which, if any, can block virus infection and those candidates could move on to clinical trials.There’s still a lot of research and testing to go, and also still a lot of hope.“The cool thing which we’re exploring now is the fact that you might be able to use them as a nasal spray and this actually gets them to the place where the virus is affecting lung tissue,” said Whiteheart.This isn’t the first time the trio of alpacas has helped medical research. Big Boy, Blue Eyes and Emperor have contributed to the university’s nanobody research for more than three years. In that time, they have helped researchers generate more than 50 nanobodies to target proteins involved in a variety of human diseases including cancer, diabetes and neurological disorders.This story was originally reported by Alex Valverde on LEX18.com. 1869
A man who police believe is the Golden State Killer will be arraigned Friday as police continue looking for more clues that connect him to the decades-old crimes.Joseph James DeAngelo, 72, was arrested Tuesday and charged with capital murder in the 1978 killing of Katie and Brian Maggiore in Sacramento County.On Thursday, FBI agents and police searched DeAngelo's home in Citrus Heights, a town about 16 miles northeast of the California capital. 456

A report says three Milwaukee Police officers were suspended for varying lengths after the arrest (involving a Taser) of Milwaukee Bucks player Sterling Brown.The Journal Sentinel says that the first police officer who confronted Brown on January 26 outside a Walgreens on Milwaukee's south side was suspended for two days.The report says two supervising officers who came to the scene later received 15 and 10 day suspensions, while other officers were reprimanded.Their names were not initially divulged. Chief of Police Alfonso Morales says retraining will be involved."I have to do things within the legal contractual boundaries that I have," said Morales about letting the public know the officers' names. 728
A new US government report delivers a dire warning about climate change and its devastating impacts, saying the economy could lose hundreds of billions of dollars by the end of the century.The federally mandated study was supposed to come out in December but was released by the Trump administration on Friday, at a time when many Americans are on a long holiday weekend, distracted by family and shopping.David Easterling, director of the Technical Support Unit at the NOAA National Centers for Environmental Information, emphasized that there was "no external interference in the report's development." He added that the climate change the Earth is experiencing is unlike any other."The global average temperature is much higher and is rising more rapidly than anything modern civilization has experienced, and this warming trend can only be explained by human activities," Easterling said.Coming from the US Global Change Research Program, a team of 13 federal agencies, the Fourth National Climate Assessment was put together with the help of 1,000 people, including 300 leading scientists, roughly half from outside the government.It's the second of two volumes. The first, released in November 2017, concluded that there is "no convincing alternative explanation" for the changing climate other than "human activities, especially emissions of greenhouse gases."The report's findings run counter to President Donald Trump's consistent message that climate change is a hoax. On Wednesday, Trump tweeted, "Whatever happened to Global Warming?" as some Americans faced the coldest Thanksgiving in over a century.But the science explained in these and other federal government reports is clear: Climate change is not disproved by the extreme weather of one day or a week; it's demonstrated by long-term trends. Humans are living with the warmest temperatures in modern history. Even if the best-case scenario were to happen and greenhouse gas emissions were to drop to nothing, the world is on track to warm 1.1 degrees Fahrenheit.As of now, not a single G20 country is meeting climate targets, research shows.Without significant reductions in greenhouse emissions, the annual average global temperature could increase 9 degrees Fahrenheit (5 Celsius) or more by the end of this century, compared with preindustrial temperatures, the report says. 2355
A man walks into an Ohio Little Caesars, buys a pizza and walks back out to his car.Happens every day.What does not happen every day is the man driving away on only three tires and getting busted for an OVI. According to Canton police, Joshua Milkovich, 28, was missing a tire as he drove his car around on Sunday night. Police say they got several calls from concerned citizens who were worried he had gotten into accident.Police found him on the 1900 block of Mount Vernon, where his car broke down.He was charged with an OVI and taken to Stark County Jail. 598
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