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Epidiolex, the first cannabis-based medication approved by the US Food and Drug Administration, is now available by prescription in all 50 states.The twice-daily oral solution is approved for use in patients 2 and older to treat two types of epileptic syndromes: Dravet syndrome, a rare genetic dysfunction of the brain that begins in the first year of life, and Lennox-Gastaut syndrome, a form of epilepsy with multiple types of seizures that begins in early childhood, usually between ages 3 and 5."Because these patients have historically not responded well to available seizure medications, there has been a dire need for new therapies that aim to reduce the frequency and impact of seizures," said Justin Gover, CEO of GW Pharmaceuticals, the maker of Epidiolex, in a written statement. "We are committed to ensuring that these patients can access this novel cannabinoid medicine that has been thoroughly studied in clinical trials, manufactured to assure quality and consistency, and is eligible to be covered by insurance for appropriate patients." 1063

Ever since their older brother competed in the Scripps National Spelling Bee years ago, twin brothers Garrett and Pierce Bryner have dreamed of making it to the bee — together.This year, they’ll see that dream become reality. “It’s kind of historical, I guess you’d say,” said Garrett, who made it to the national bee — without his brother — last year.Previously, twins would never have been able to make it to the bee together, as one would have always beaten the other out. But thanks to new qualifying rules put in place this year which incorporate a point system, two sets of twins are now going to be on the national stage for the first time in the spelling bee's 91-year history: the Bryner twins, and another set of twins from Mississippi.Garrett’s brother Pierce will become the third sibling in the Bryner family to attend the bee.Their mom, Liz Bryner, who has shepherded her kids through her share of bees, says that while the two will be nervous, for the parents, its on a whole other level.“I think nothing compared to the Bee in terms of the stress level,” Liz said from her home in Utah. “If you look around at the parents they’re often more nervous than the kids. I think it’s really a nail-biting experience.”Garret and Pierce say they can be competitive when it comes to studying. "Sometimes the other one jumps in tries to spell the word before the other one,” Pierce said. Ultimately they hope for the best for each other.“I just cheer him on,” Pierce said.They’ve been studying as much as they can, Liz said, but as eighth grade boys, surrounded by the rugged landscape of Utah, their attention span only lasts so long before they want to get back outside and hop on their bikes.“I don’t think we’ve ever gone longer than probably 90 minutes at a time,” she said. “That’s about as long as anyone’s been willing to do.”“To know that they can both understand what it’s like to be there at the national bee to compete, and it’ll be something they share,” she said. “The fact that they can share this experience is just incredible as a mom.”ESPN, which broadcasts the bee, has seen viewership numbers for the annual contest that have hovered around one million people. The twins’ trick to calm their nerves?“Focus more on the words than the audience,” Garret said with a smile. Editor’s note: This publication is owned by the E.W. Scripps Company which sponsors the Scripps National Spelling Bee. 2471

Facebook says it has removed a small network of fake accounts and pages that originated in China and focused on disrupting political activity in the U.S. and several other countries.The accounts posted material both in support of and against presidential candidates Pete Buttigieg, Joe Biden and Donald Trump.Facebook said they removed 155 accounts, 11 pages, 9 groups and 6 Instagram accounts.Facebook did not link the network directly to the Chinese government. It said the people behind the network tried to conceal their identity and location via virtual private networks and other methods.U.S. intelligence officials have identified China as one of several countries, along with Russia and Iran, who they say could look to interfere in the 2020 election. In an August public assessment, the country’s chief counterintelligence official, William Evanina, said officials had determined that Beijing regards Trump as unpredictable and wants to see him lose to Biden.The U.S.-focused activity was the most limited and gained almost no following, Facebook said.Facebook said the network focused mainly on Southeast Asia, where it posted in Chinese, Filipino and English about global news and current events. These included Beijing’s interests in the South China Sea, Hong Kong, support for Philippines President Rodrigo Duterte and his daughter’s potential run in that nation’s 2022 presidential election, and criticism of Rappler, an independent news organization in the Philippines.Facebook also removed a second network originating in the Philippines. In connection with this network, Facebook removed 57 accounts, 31 pages and 20 Instagram accounts. 1661

Father and son stories aren't supposed to look like this."I was praying for my friends and family to be OK," said Braden Freidkes, a freshman at Marjory Stoneman Douglas High School. He was inside the school when a gunman started shooting.Braden eventually made it out and into his parents' arms. They had been trying to reach him repeatedly and up until that point had feared the worst. "We were one of the lucky ones. We were able to get him and he was safe," said John Freidkes, Braden's father.But now Braden and his dad have a shared experience, in a way they could have never imagined.  605

ESCONDIDO, Calif. (KGTV) -- A 17-year-old was killed early Saturday morning following a hit-and-run in unincorporated Escondido. According to California Highway Patrol, the crash happened on Mesa Rock Road near Mesa Ranch Drive around 12:30 a.m. CHP says the 17-year-old female was standing outside a vehicle parked on the right shoulder having a conversation with four friends. Three of the individuals, including the teen, crossed the road from east to west. As they crossed, CHP says either a white Toyota SUV or a pickup truck speeding northbound struck the teen."The California Highway Patrol Oceanside Area is asking the public for assistance in locating a 2008 to 2012 model year range second generation, Toyota Highlander, pearl white in color. The vehicle will have damage to the right front headlight area and right-side mirror," said CHP Ofc. Mark Latulippe. 877