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WASHINGTON, May 11 (Xinhua) -- Johns Hopkins University researchers have demonstrated that human liver cells derived from adult cells coaxed into an embryonic state can engraft and begin regenerating liver tissue in mice with chronic liver damage.The work, published Wednesday in the journal Science Translational Medicine, suggests that liver cells derived from so- called "induced-pluripotent stem cells (iPSCs)" could one day be used as an alternative to liver transplant in patients with serious liver diseases, bypassing long waiting lists for organs and concerns about immune system rejection of donated tissue."Our findings provide a foundation for producing functional liver cells for patients who suffer liver diseases and are in need of transplantation," says Yoon-Young Jang, assistant professor of oncology at the Johns Hopkins Kimmel Cancer Center. "iPSC-derived liver cells not only can be generated in large amounts, but also can be tailored to each patient, preventing immune-rejection problems associated with liver transplants from unmatched donors or embryonic stem cells." A microsopic view shows human embryonic stem cells in various stages of differentiation into liver cells in this photo taken at Stanford University and released by the California Institute for Regenerative Medicine, March 9, 2009iPSCs are made from adult cells that have been genetically reprogrammed to revert to an embryonic stem cell-like state, with the ability to transform into different cell types. Human iPSCs can be generated from various tissues, including skin, blood and liver cells.Although the liver can regenerate in the body, end-stage liver failure caused by diseases like cirrhosis and cancers eventually destroy the liver's regenerative ability, Jang says. Currently, the only option for those patients is to receive a liver organ or liver cell transplant, a supply problem given the severe shortage of donor liver tissue for transplantation. In addition, mature liver cells and adult liver stem cells are difficult to isolate or grow in the laboratory, she says. By contrast, iPSCs can be made from a tiny amount of many kinds of tissue; and the embryonic stem- like iPSCs can grow in laboratory cultures indefinitely.For the study, Jang and colleagues generated human iPSCs from a variety of adult human cells, including liver cells, fibroblasts ( connective tissue cells), bone marrow stem cells and skin cells. They found that though the iPSCs overall were molecularly similar to each other and to embryonic stem cells, they retained a distinct molecular "signature" inherited from the cell of origin.

BEIJING, Feb. 5 (Xinhua) -- China's meteorological authority said Saturday that a cold snap would sweep north China over the next few days, bringing down temperatures and carrying gusty winds.Temperatures in some parts of Xinjiang Uygur Autonomous Region, Inner Mongolia Autonomous Region and northeast China will drop 4 to 6 degrees Celsius over the weekend, the National Meteorological Center (NMC) said in a statement on its website.In most areas north to the Huaihe River, the temperatures will go down 4 to 6 degrees Celsius, or even 8 to 10 degrees Celsius in some parts of the areas between Monday and Tuesday.The cold front would then move southward to affect more areas in the eastern and southern parts of the country.The NMC said some areas in northern and western Xinjiang Uygur Autonomous Region, the eastern part of Inner Mongolia, Sichuan Basin and most of the northeast China, the western parts of the areas south to the Yangtze River will see light to moderate snow or sleet in the forthcoming three days.Fog continued to shroud south China Saturday, reducing visibility to less than 200 meters in parts of Hunan, Hubei, Jiangxi, Sichuan and Fujian provinces, as well as Chongqing City.

SAN FRANCISCO, April 19 (Xinhua) -- YouTube announced Tuesday that the much-anticipated British royal wedding of Catherine Middleton and Prince William will be live streamed on the website' s live channel.Next Friday, the live stream will follow the wedding procession, marriage ceremony at Westminster Abbey and balcony kiss, said YouTube in its official blog. The official channel (www.youtube. com/theroyalchannel), will have live blog commentary of the event, and users can also upload video wishes for the couple on the site."This one is already heralded as the first of the Internet age, where for the first time in thousands of years of royal history, the moment will be captured on-line and preserved forever," said the blog post.YouTube, whose parent company is Google, will provide the technical support for the broadcast and the footage will be provided by the BBC.On April 8, YouTube launched live streaming service YouTube Live, including a home page where users can view live events and a live steaming platform on which partners with accounts could stream live content.

CARACAS, March 30 (Xinhua) -- The number of confirmed cases of the A/H1N1 influenza in Venezuela has risen to 482 this year, Health Minister Eugenia Sader said on Wednesday.According to the latest report, the state of Merida in southeastern Venezuela has 189 A/H1N1 influenza cases, the biggest number ever reported, which was followed by the Capital District of Caracas with 112 cases. The other 181 cases were confirmed in 17 of 24 Venezuelan states.The first case for this year was reported in Merida earlier this month.Sader said that the Venezuelan government was trying to prevent the spread of the disease. Some 3 million people have been vaccinated against the virus.Three patients infected with the A/H1N1 influenza virus have died in the country this year, according to Sader.The A/H1N1 influenza can cause deadly pneumonia if it is not treated early.

WASHINGTON, Jan. 19 (Xinhua) -- China and the United States have agreed to further boost their bilateral relationship toward a cooperative partnership for the benefit of the whole world, President Hu Jintao said Wednesday.The visiting Chinese leader presented the course forward at a joint press conference at the White House with his U.S. counterpart Barack Obama following their eighth meeting in two years.During the talks, conducted in "a candid, pragmatic and constructive atmosphere," the two sides reached "important agreement on China-U.S. relations and major international and regional issues of shared interests," according to the Chinese president.Chinese President Hu Jintao (2nd L) holds a bilateral meeting with U.S. President Barack Obama (2nd R) at the White House in Washington, the United States, Jan. 19, 2011. "We both agree to further push forward the positive, cooperative and comprehensive China-U.S. relationship," Hu said, adding that both sides also pledged to forge "a China-U.S. cooperative partnership based on mutual respect and mutual benefit" for the benefit of the two countries and beyond.Meanwhile, the two sides "should firmly adhere to the right direction," respecting each other's core interests and handling their relations with a long-term perspective, which will enable both countries to make greater contributions to world peace and development, he said.Citing the growing number of global challenges, the Chinese president stressed that Beijing and Washington "share expanding common interests and shoulder increasing common responsibilities."Accordingly, he added, the two sides have agreed to strengthen exchanges and cooperation in economy, trade, environment, education, science and technology, non-proliferation and counter-terrorism among many other fields.During Hu's ongoing state visit, the two countries signed a number of cooperation agreements. "These will inject fresh momentum into our bilateral cooperation and create a great many job opportunities for our two countries," Hu said.He added that he and Obama also discussed some disagreements in the economic and trade area, with both sides pledging "to continue to appropriately resolve these according to the principle of mutual respect and consultation on an equal footing."Commenting on the relations between the countries's armed forces, Hu said, "We believe expansion of military exchanges and cooperation will be conducive to deepening mutual trust between our two countries."On the situation on the Korean Peninsula, he said that both countries agreed to work together with relevant parties to maintain peace and stability on the peninsula, promote denuclearization of the peninsula and achieve lasting peace and security in Northeast Asia.The Chinese leader reaffirmed China's firm commitment to the path of peaceful development and a win-win strategy of opening up, and appreciated Obama's commitment to a positive and constructive China policy."China is a friend and partner of all countries, and China's development is an opportunity for the world," he said.