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2025-05-31 17:09:33
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  中山大便出血 原因   

WASHINGTON, Oct. 6 (Xinhua) -- The U.S. Food and Drug Administration (FDA) and the National Institutes of Health (NIH) announced Thursday a joint, large-scale, national study of tobacco users to monitor and assess the behavioral and health impacts of new government tobacco regulations.The initiative is the first large-scale NIH/FDA collaboration on tobacco regulatory research since the U.S. Congress granted FDA the authority to regulate tobacco products in an act in 2009. Scientists at NIH's National Institute on Drug Abuse and the FDA's Center for Tobacco Products will coordinate the effort."The launch of this study signals a major milestone in addressing one of the most significant public health burdens of the 21st century," said FDA Commissioner Margaret Hamburg in a statement. "The results will strengthen FDA's ability to fulfill our mission to make tobacco-related death and disease part of America's past and will further guide us in targeting the most effective actions to decrease the huge toll of tobacco use on our nation's health."Investigators will follow more than 40,000 users of tobacco- product and those at risk for tobacco use ages 12 and older. They will examine what makes people susceptible to tobacco use; evaluate use patterns and resulting health problems; study patterns of tobacco cessation and relapse in the era of tobacco regulation; evaluate the effects of regulatory changes on risk perceptions and other tobacco-related attitudes; and assess differences in attitudes, behaviors and key health outcomes in racial-ethnic, gender, and age subgroups."We are pleased to collaborate with the FDA on this study that may provide us with a better understanding of the impact of product regulation on tobacco prevention and cessation," said NIH Director Francis Collins.While smoking rates have dropped significantly since their peak in the 1960s, nearly 70 million Americans ages 12 and older were current users of tobacco products in 2010. As a result, death and disease caused by tobacco use is still a tremendous public health burden. Tobacco use is the leading preventable cause of disease, disability, and death in the United States. Cigarette smoking results in more than 443,000 premature deaths in the United States each year -- more than alcohol, illegal drug use, homicide, suicide, car accidents, and AIDS combined.

  中山大便出血 原因   

WASHINGTON, Oct. 13 (Xinhua) -- U.S. researchers have corrected sickle cell disease in adult laboratory mice that had been bred to have the inherited blood disorder by activating production of a special blood component, according to a study published online Thursday in the journal Science.Sickle cell disease results from an abnormality in hemoglobin, the protein found in red blood cells that is responsible for transporting oxygen throughout the body. People living with sickle cell disease have two copies of an altered gene that produces sickle hemoglobin instead of normal adult hemoglobin. Sickle hemoglobin changes shape after releasing its oxygen, causing the red blood cell to become stiff, misshapen and sticky, and slowing blood flow to tissues. This process damages organs and causes pain.The study tested a new approach to increasing the production of a third form of hemoglobin -- fetal hemoglobin. Production of fetal hemoglobin predominates before birth, but turns off thereafter as adult hemoglobin production takes over. People with sickle cell disease are unable to make normal adult hemoglobin, and instead make sickle hemoglobin starting in infancy.An elevated level of fetal hemoglobin within the red blood cell reduces the tendency of sickle hemoglobin to change the shape of red blood cells. Considerable research has shown that the drug hydroxyurea increases production of fetal hemoglobin and reduces the number of pain crises and other complications of sickle cell disease in adults and children. However, not all patients respond well to hydroxyurea, and adverse side effects are a concern.The current study explores a more targeted approach to increasing fetal hemoglobin production. It builds upon earlier studies that discovered a protein called BCL11A normally suppresses the production of fetal hemoglobin soon after birth. The researchers viewed the BCL11A protein as a target for therapy and decided to see what would happen if they blocked production of the protein.The paper details how the research team silenced the mouse gene that produces the BCL11A protein in mice with sickle cell disease. Silencing the gene turned off production of the BCL11A protein and allowed the adult mice to continue to produce fetal hemoglobin. It appears to have eliminated disease symptoms without affecting other aspects of blood production."This discovery provides an important new target for future therapies in people with sickle cell disease," said Susan Shurin, acting director of the U.S. National Heart, Lung, and Blood Institute, which co-funded the study. "More work is needed before it will be possible to test such therapies in people, but this study demonstrates that the approach works in principle."Approximately 100,000 Americans live with sickle cell disease. It is most prevalent in people of African, Hispanic, Mediterranean, and Middle Eastern descent. There is no widely available cure for sickle cell disease. Bone marrow transplants have cured some patients, but the treatment is not without risk and most patients do not have relatives who can donate compatible and healthy bone marrow to them.

  中山大便出血 原因   

WINDHOEK, Nov. 29 (Xinhua) -- An agreement on Economic and Technical Co-operation was signed here on Tuesday between the Chinese and Namibian governments.The agreement was signed after Namibian Cabinet ministers and officials from various ministries held talks with Chinese State Councilor Liu Yandong, who arrived in Namibia on Tuesday for a three-day official visit.Minister of Presidential Affairs Albert Kawana, who is the Acting Director-General (DG) of the National Planning Commission (NPC), and Ambassador of China to Namibia Wei Ruixing signed the agreement.The two also exchanged letters on the provision of office supplies and solar energy equipment to the Namibian government by the Chinese government.During their talks, Liu highly spoke of the steady, healthy development of the relations between the two countries.She said the substantial cooperation have been obtained on agriculture, mining and human resources. Great achievements have been made in exchanges of culture and education.The state councilor also said China would like to work together with all African countries including Namibia to promote the development of people-to-people exchanges.Namibia's Deputy Prime Minister Marco Hausiku proposed future cooperation with China in visual and performing arts.He said the Directorate of Arts in the Ministry of Youth, National Service, Sports and Culture is keen to develop future relationships that will lead to bilateral exchanges in arts education, assistance in the development of small arts businesses, the promotion of arts through the exchange of information on arts and participation in events in the respective countries."This can be achieved through the development of ties between the relevant institutions responsible for these areas, such as the line ministries responsible for arts, arts education colleges, performance theaters, art galleries and organizers of events such as festivals and expos," he noted.He also encouraged exchanges between musicians in the sphere of composition, conducting, and instrumental playing in both folklore and symphonic genres, and therefore invited China in the development of Namibia's National Symphony Orchestra.Hausiku also proposed for scholarships in information and communication technology (ICT), particularly policy development and regulatory framework, and linkages with Chinese ICT institutions for exchange purposes.

  

JERUSALEM, Dec. 11 (Xinhua) -- Kfir Damari, a communication systems engineer, has a dream: to land a miniature spacecraft on the moon sometime in 2013.Damari is one of the founders of Team SpaceIL, a non-profit organization representing Israel in the Google Lunar X Competition. The prize: 20 million U.S. dollars to the first of the 26 international teams currently registered that lands an unmanned craft on the moon, moves it a minimum of 500 meters across the lunar surface and transmits live high-resolution images back to earth."It's a tough mission, but I believe that if everyone in Israel joins hands it's possible," Damari told Xinhua.It is exactly the kind of entrepreneurial spirit that Israel, a country largely void of natural resources, counts on to make it a global leader in technological innovation.The two other men behind the initiative are Yonatan Winetraub, 25, a systems engineer at Israel Aerospace Industries (IAI) and a graduate of NASA's International Space University, and Yariv Bash, 31, a computer scientist and electronics engineer. The three first met at an innovation conference held by IAI a year ago.They describe the lander as a nano-satellite, whose design was revealed at the project's official inauguration ceremony on Thursday. The vessel weighs 100 kg, 80 percent of which are fuel, and is outfitted with rocket boosters and a panoramic camera."It's somewhat of a cellular phone sitting on a large fuel tank. All the technology that we require is basically contained in a typical smartphone with its communication and imaging features," Damari said.Launched in 2007, the Lunar X Prize aims to encourage space enthusiasts and engineers worldwide to develop cheap technologies for robotic space exploration.The Israelis have slated a modest 15 million U.S. dollars for the endeavor, 90 percent of which must come from private contributions according to the competition's rules. They have already raised 3.5 million dollars.The fact that they have formed a non-profit NGO in itself is worthy of praise. Most other teams have obtained the patronage of private corporations for whom money is not a problem, with some reportedly allotting up to 100 million U.S. dollars.To compensate for the disparities in funding, Damari and his partners have enlisted the support of 120 local volunteers, many of them engineers holding top positions in the technological and scientific community as well as the country's leading defense industries.Rona Ramon, the widow of Israeli astronaut Ilan Ramon killed aboard the Columbia Space Shuttle in 2003, was one of the sponsors too.In a bid to keep costs down, SpaceIL is heavily relying on the existing knowledge accumulated by Israel's defense industries over the past decades in building and launching mainly small, lightweight communications and military surveillance satellites into space.The challenge, Damari said, is to take that know-how a step further. The professionals who have volunteered for the project, among them some of Israel's most revered space experts, are currently grappling with several issues, including the ignition system, optic-visual navigation, beaming imagery to earth and the intricacies of enabling the nano-satellite a smooth lunar landing.SpaceIL is still searching for a third party that they will lease to launch their vehicle into space. Once there, they will have to navigate it to the moon on their own.While 20 million U.S. dollars is a major motivator for anyone, the Israelis said they're not seeking personal gain, but rather plan to invest the prize money in the vision that originally prompted their registration in December last year: inspiring the country's younger generation to pursue engineering and the sciences and to dream big, just like Neil Armstrong did when he disembarked from the Apollo 11 and took the first step on the moon in 1969.The funds, they said, will be funneled to educational programs that seek to rejuvenate youths' interest in science disciplines, which have been on the decline in the country's high schools in recent decades."We hope to attract the next generation of kids, to enable them to be engineers and scientists and to make sure that we have more people that can build spaceships in Israel in the future," said Damari.He and the other men behind the initiative also acknowledge that their motives are no less driven by patriotism. Winning the Lunar X has the potential to create national pride and put Israel "on the map as a start-up nation" by accomplishing a feat reserved for superpowers."The moon is something you see every day. I think that for me personally, space exploration is the way to enlist the nation to do something that has not yet been done," said Damari, who started programming aged six and wrote his first computer virus aged 11."It's also about exploring new borders, going the distance. (The project) will leverage Israel's space industry. I'm sure that all the industries that will partner with us will learn a lot and develop new applications, especially for the civilian market," he said.On Thursday, Israeli President Shimon Peres, whose name has become synonymous with the nation's hi-tech industries, honored the trio by unveiling their model at the ceremony held at MABAT -- IAI's missiles and space division near Tel Aviv."More than Israel is leading technology, it is likely to lead Israel. It's the key to our economy ... If they win the prize, and I'm sure they will, it will also reward Israel with the deepest appreciation and the best deterrence," Peres told a crowd of senior executives from local defense industries."I admire your audacity and vision," he complimented the three scientists.Will they realize their ambition? Damari expressed humble optimism, "It's not easy, but certainly possible ... We believe we can win."

  

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