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Johnson & Johnson announced it has paused its coronavirus vaccine trials on Monday following an “unexplained illness” among one of its participants.Johnson & Johnson stressed that adverse events during trials are expected, and a pause gives researchers an opportunity to review all of the medical information before moving forward with the trial. Johnson & Johnson added that it’s not always immediately known if the affected person received a placebo or a study treatment.Among the trials paused was Johnson & Johnson’s multi-country “ENSEMBLE” vaccine, which entered Phase 3 testing in September. Johnson & Johnson said last month that its goal was to seek an emergency use authorization approval in early 2021.The FDA noted that a vaccine candidate must be at least 50% effective to receive emergency use authorization. Vaccine candidates should include a median follow-up duration of at least two months after completion of the full vaccination regimen to help provide adequate information to assess a vaccine’s risk-benefit.According to the FDA, a typical Phase 3 trial would take one to three years.“NIH is committed to supporting several Phase 3 vaccine trials to increase the odds that one or more will be effective in preventing COVID-19 and put us on the road to recovery from this devastating pandemic,” said NIH Director Francis S. Collins, M.D., Ph.D. “We also know that preventing this disease could require multiple vaccines and we’re investing in those that we believe have the greatest potential for success.” 1554
JEFFERSON COUNTY, Colo. — It’s easy to spot deer or wild turkeys along Parmalee Gulch Road north of Highway 285 in Jefferson County. But what's catching the eyes of speeding drivers now is a creature of myth and legend.On Ron DiDonato's Indian Hills property is a 5-foot pink pig with wings that flap, attached to a 10-foot pole.“I knew this would be an attention-getter and it definitely has been,” DiDonato said. “At first, I didn’t know if it was going to be good or not because they were stopping in the street to look at it."DiDonato said he decided to create the flying pig to play off the saying that the only time traffic would slow down on Parmalee Gulch Road is when pigs fly.“I couldn’t go out, couldn’t do anything, so I decided to do this just to slow the traffic down and it sure has helped,” DiDonato said. “I’m not an artist of any sort, so I did papier-maché, and to make it weatherproof I fiberglassed it. Then painted it pink and put lipstick on it.”Ron needed newspaper for his papier-maché project, which his granddaughter helped with, so he contacted Terri Wiebold, publisher of the Castle Pines Connection.“Having done some pandemic purging ourselves, The Castle Pines Connection had set aside some archived papers to recycle, and we were happy to oblige DiDonato’s request," Wiebold said.DiDonato said so far, it seems to be working — people are so surprised to see the flying pig, they slow down to take it all in.DiDonato said he blames the speeding problem on the growth that has been coming as fast as the drivers down these foothill roads and in this part of Jefferson County.Mike Taplin, public information officer for the Jefferson County Sheriff’s office said he doesn't know if the flying pig has helped slow speeding traffic."If people post something or do something to help remind drivers to follow traffic laws and drive with safety in mind, we do not have a problem," he said. "The public should not attempt to enforce traffic laws themselves — that needs to be done by law enforcement agencies.”DiDonato said he plans to leave it up all winter and for as long as it keeps working to slow down drivers who like to push well past the 30 mph speed limit on the straight stretch of road through his neighborhood.“All my neighbors are really happy I did it. Maybe we’ll do some more," he said.This story was first reported by Jayson Luber at KMGH in Denver, Colorado. 2408
KANSAS CITY, Kansas – The Kansas Attorney General’s Office Tuesday released indictments against three more officials and entities in connection to the Schlitterbahn Waterpark death in 2016. Jeffrey Wayne Henry, John Timothy Schooley, and Henry & Sons Construction Company, Inc. were indicted by a Wyandotte County Grand Jury.The trio faces reckless second-degree murder charges in addition to aggravated battery and aggravated child endangerment charges stemming from others who rode Verruckt at the company’s Kansas City, Kansas waterpark.Henry was taken into custody Monday by U.S. Marshals in Cameron County, Texas. A spokeswoman for the attorney general’s office said Schooley remains at large.Henry is co-owner of Schlitterbahn and is connected to Henry and Sons Construction Company.Schooley played a key role in the design of Verruckt.It was on Verruckt that then 10-year-old Caleb Schwab died in August 2016.Last week, the attorney general’s office charged the company and its park operations manager at the time of the incident, Tyler Miles, in connection to Schwab’s death.Miles pleaded not guilty in a court hearing in Wyandotte County on Friday. 1189
JAMUL, Calif. (KGTV) - Anabel and Dewey will celebrate 21 years of marriage this year, but in the smallest fraction of that time, everything from their life was destroyed.The couple lived in their Jamul home with Anabel’s mother and their five cats. Saturday, Anabel was at work and her mother was out of town. Dewey saw there was a fire in the distance, but felt confident it would be contained quickly, like most of the fires that spark in their area. He left the home, not knowing it would be the last time he saw it standing.That night, flames engulfed their home. Video captured shows it on fire, with firefighters nearby trying to find the flames, but they were unsuccessful. The five cats were not able to be saved.RELATED COVERAGEVALLEY FIRE: Resources on where to get help, air quality, and animal sheltersINTERACTIVE MAP: Valley Fire erupts in Japatul Valley areaPhotos: Valley Fire erupts in East CountyAnabel said they have not been able to return home to see the damage, and found out about the loss from images online, a realization that was hard to process.“But the more I looked at it, that was our house. That was the car, my mom’s car, right by the house that was on fire,” she said.In the fire, they lost their cats and a lifetime of memorabilia. At home, they had many family members' ashes, including Dewey’s mother, Anabel’s stepfather and also Anabel’s son, who passed away from cancer this year.Also lost were sentimental items from Dewey’s 22 years in the Navy, including his shadow box and his uniform, which he intended to wear when he pinned his mentees, an honor in the military community.RELATED COVERAGE:Red Cross evacuation sites provide outdoor shelter and hotel lodging amid pandemicABC 10News forecast for San Diego County“They’ve asked to make sure that I pin them. And you can buy a new uniform, yeah, but you’d like to wear the one you wore,” he said, holding back tears.Despite the long list of losses, the couple said they aren’t giving up.“It’s just [beginning] again, it’s not the end and that’s the way it’s going to be,” said Dewey.Their nephew started a GoFundMe to help them get back on their feet. They said the support from friends and strangers already has touched them in ways they didn’t know were possible.“We are overwhelmed. I don’t know what the proper adjective is or the expression to explain the level of which we are thankful to so many friends, family and strangers who are being extremely generous,” said Dewey. 2480
JULIAN (CNS) - A motorcyclist was killed in a crash near Julian on Saturday.California Highway Patrol officers headed to state Route 79 near Sunrise Highway about 1:50 p.m. for a report that a Toyota 4Runner had struck a motorcycle and pinned the rider underneath the vehicle, according to a CHP incident log.The motorcyclist was pronounced dead at the scene, according to Cal Fire San Diego. No identifying information on the victim was available.One-way traffic control was in place while authorities investigated and worked to clean up the crash, according to the CHP. 579