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Have you ever lied on a work resume? Well, 75 percent of human resources managers surveyed by Career Builder say they’ve spotted a lie on applicants’ resumes.Here were some of them: 189

GUERNEVILLE, Calif. (AP) — Two communities in Northern California's wine country were accessible only by boat Wednesday after a rain-swollen river overflowed its banks following a relentless downpour across an already waterlogged region.The small city of Guerneville north of San Francisco "is officially an island," with the overflowing Russian River forecast to hit its highest level in about 25 years, the Sonoma County Sheriff's Office said in a statement."Nobody is coming or going from the Guerneville area at this time," said sheriff's Sgt. Spencer Crum. The nearby town of Monte Rio was also isolated by floodwaters and all roads leading to it were swamped.The still rising Russian River was engorged by days of rain from western U.S. storms that have also dumped heavy snow in the Sierra Nevada, throughout the Pacific Northwest and into Montana, where Gov. Steve Bullock signed an emergency order to help keep up the supply of heating fuel amid frigid temperatures.Snow from the storms closed roads and schools and toppled trucks and trees from Oregon to Montana and an avalanche in the Sierra prompted Amtrak to suspend rail service between Sacramento and Reno, Nevada.The Russian River topped 42 feet (13 meters) Wednesday afternoon, when television helicopter footage showed homes underwater and cars submerged. It could crest at more than 46 feet (14 meters) by Wednesday night, officials said. About 4,000 residents in two dozen river communities were ordered to evacuate Tuesday evening but officials estimate only about half heeded the orders, Crum said.Jeff Bridges, co-owner of the R3 Hotel in Guerneville, said he and others who stayed behind were well prepared to ride out the storm. He and employees spent most of the night moving computers, business records and furniture to second-floor room. Reached by telephone, Bridges said there was about 7 feet (2 meters) of water at his two-story home in Guerneville Wednesday but was not worried."As long as everybody is safe, dry and warm, it's all fine. You just ride it out," said Bridges, noting that this flood was the fourth he's experienced in 33 years.He added: "People in Florida have hurricanes, people in Maine have blizzards; we have floods," he said. "It's the price we have to pay to live in paradise."Several areas in California set record-high rainfall totals, including nearby Santa Rosa, which had nearly 8 inches (20 centimeters) of rain in one day. The often-waterlogged Venado weather station 5 miles (8 kilometers) from Guerneville recorded more than 20 inches (50 centimeters) of rain in 48 hours.In the Sierra Nevada, which has already seen a month of heavy snow, two Amtrak trains together carrying nearly 300 passengers stopped and reversed directions because of an avalanche that closed railroad tracks. Service on Amtrak's California Zephyr between Reno and Sacramento, California, has been suspended until weather conditions improve, Amtrak spokeswoman Kimberly Woods said.California officials were also concerned about potential mudslides in saturated wine country hillsides and in areas scarred by wildfires in 2017.A mudslide Tuesday near Monte Rio trapped a man and a woman before they were rescued, messy but unharmed."I fell into the mud when the tree fell over the top of me. It happened so fast you don't even know," Kear Koch told KGO-TV.Elsewhere in the area, several people had to be rescued from cars stranded while motorists tried to drive through flooded roads. Nina Sheehan, who is visiting from North Carolina, had to abandon her rental SUV after it got stuck in a flooded hotel parking lot."We made a decision to take the rental car through the waist-high water and we got two thirds of the way and then the car stalled," she said. "Do not try to go through any water over a foot high because you never know what you're going to find."Firefighters in Monte Rio worked through the night pulling people out of cars stuck in flooded roadways and getting people out of their homes as water approached, Fire Chief Steve Baxman told the Press-Democrat newspaper of Santa Rosa."We took 17 people out of cars and houses during the night. Too many people are driving into water," he said.Other waterways, including the Napa River, also were expected to overflow their banks as an ocean-spanning plume of moisture continued tracking through the West. 4360

Genetic testing company 23andMe has been given federal approval to sell at-home kits that test for three breast cancer gene mutations.This will be the first direct-to-consumer DNA test for these particular breast cancer gene mutations, the Food and Drug Administration said on Tuesday.A spokeswoman for 23andMe said the test for the three BRCA1/BRCA2 breast cancer gene mutations will be added "in the coming weeks" to the broader Health + Ancestry services, with no increase to the existing 9 cost.The test can only detect three out of more than 1,000 known BRCA mutations, according to the FDA. The BRCA1/BRCA2 hereditary mutations occur in about 2% of Ashkenazi Jewish women, but rarely occur in anyone else, the agency said in a press release."The test also does not provide information on a person's overall risk of developing any type of cancer," the FDA added.23sandMe already tests for genetic health risks for diseases like Parkinson's and Alzheimer's, along with wellness reports for things like lactose intolerance and saturated fat, and ancestral composition including Neanderthal ancestry.In 2013, the FDA ordered the company to stop sales of its home-testing kits, saying the Alphabet-backed company had failed to prove the validity of its product.Related: 23andMe gets funding for drug developmentAnne Wojcicki, who founded the company in 2006, called the FDA shutdown a "transformative moment" that prompted 23andMe to branch into drug development."Thank you to the FDA for hard work and progress on innovation," she tweeted on Tuesday.In 2015, 23andMe received approval from the FDA to test customers for whether they are carriers of certain disease-carrying genes that could be passed on to their children. In early 2017, the company received approval to issue genetic health risk reports.In September of last year, the company said it received 0 million in funding from Sequoia Capital to develop drugs based on user DNA.The-CNN-Wire? & ? 2018 Cable News Network, Inc., a Time Warner Company. All rights reserved. 2050

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HAMPTON ROADS, Va. - As coronavirus continues to rage across the country, scientists are inching closer to developing a COVID-19 vaccine.Dr. Doug Mitchell used to be a pediatric infectious diseases specialist at CHKD and EVMS. He is currently the medical director of CHKD Medical Group and a pediatrician at Norfolk Pediatrics.“If we’re able to stick to the science in developing the vaccine, then that would be comforting if we could stick to the science and develop an effective and safe vaccine,” said Mitchell.Mitchell said the speed at which researchers are developing a vaccine to combat COVID-19 is nothing short of a miracle, but sticking to the clinical science behind the advancement is key for an effective and safe vaccine - and that takes time.“The stated goal that I saw by the CDC and/or FDA of wanting a vaccine that shows at least 50% protection and six months of safety data, that takes time,” he said. “We need a chance to show the safety profile of any new vaccine under the parameters of following the best science that we could follow.”Mitchell understands the process involved in developing a vaccine.More than 20 years ago, he was an investigator in several pediatric clinical trials. Many of the vaccines that came out of his lab are still used in children today.While there are still growing concerns about vaccines, the benefits outweigh the risks.“The flu vaccine clearly saves lives, clearly prevents illnesses, but it’s not 100% protective either, but we know it does have benefits,” Mitchell said. “The advantage there is the flu vaccine has been out for decades and we know its safety profile.”Similar to the rapid speed of developing a COVID-19 vaccine, Mitchell said a vaccine for H1N1, better known as the swine flu, was quickly put on the market.“The difference is, we already had decades of history of flu vaccines and their safety, so all that happened was developing the same flu vaccine that was protective against a different strain,” he said. “That’s a different ballgame than starting a vaccine against a totally different virus.”While the research continues, the fight against COVID-19 is far from over.According to Mitchell, the spread of the virus decreases when you reach heard immunity where enough of the population is immune.This story was first reported by Antoinette DelBel at WTKR in Norfolk, Virginia. 2363