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THE HAGUE, June 1(Xinhua) -- Five people in the Netherlands have been sickened with an unusual strain of the E. coli bacteria, the institute for public health (RIVM) reported Wednesday.Of the five patients, four also suffered from intestinal problems and renal failure. The five who are infected all had recently been in Germany.The patients were infected with enterohaemorrhagic E.coli, or EHEC, a particularly deadly strain of the common bacteria found in the digestive systems of cows, humans and other mammals.The outbreak has hit at least eight European countries but virtually all of the sick people either live in Germany or recently traveled there.Medical authorities appeared no closer to discovering either the source of the infection or the mystery at the heart of the outbreak: why the unusual strain of the E. coli bacteria appears to be causing so many cases of hemolytic uremic syndrome, which attacks the kidneys and can cause seizures, strokes and comas.Earlier this week German researchers showed that Dutch cucumbers were not the cause of the contamination."It is essential to quickly find the source, as long as that is not found, the contamination can spread. It's a very aggressive bacteria and many people are seriously ill," a RIVM spokesman said.

WASHINGTON, July 27 (Xinhua) -- The solar-powered, Jupiter- bound Juno spacecraft was secured into place on top of its rocket Wednesday in preparation for launch next month, the U.S. National Aeronautics and Space Administration (NASA) announced.The launch period for Juno opens Aug. 5 and extends through Aug. 26. For an Aug. 5 liftoff, the launch window opens at 11:34 a.m. EDT (1534 GMT) and remains open through 12:43 EDT (1643 GMT).Juno will arrive at Jupiter in July 2016 and orbit its poles 33 times to learn more about the gas giant's interior, atmosphere and aurora."We're about to start our journey to Jupiter to unlock the secrets of the early solar system," said Scott Bolton, the mission 's principal investigator from the Southwest Research Institute in San Antonio. "After eight years of development, the spacecraft is ready for its important mission."

BEIJING, Aug. 12 (Xinhuanet) -- The risk of developing coronary heart disease is 25 percent higher for women smokers compared with men, according to a study published in the British medical journal "The Lancet".The authors say this could be due to the physiological differences between the sexes with cigarette smoke toxins having a more potent effect on women.The study by Dr Rachel R Huxley from the University of Minnesota and Dr Mark Woodward from Johns Hopkins University involved a meta-analysis of around four million individuals and 67,000 coronary heart disease events from 86 studies.The researchers found that the pooled adjusted female-to-male relative risk ratio (RRR) of smoking compared with not smoking for coronary heart disease (CHD) was 1.25 (25 percent) higher for women.This RRR increased by 2 percent for every additional year of follow-up, meaning that the longer a woman smokes, the higher her risk of developing CHD becomes compared with a man who has smoked the same length of time.The authors say, "The finding lends support to the idea of a pathophysiological basis for the sex difference. For example, women might extract a greater quantity of carcinogens and other toxic agents from the same number of cigarettes than men. This occurrence could explain why women who smoke have double the risk of lung cancer compared with their male counterparts."Worldwide, there are 1.1 billion smokers, of whom a fifth are women.According to the Tobacco Atlas, India, with around a crore female smokers, ranks third in the top 20 female smoking populations across the globe, only the U.S. with 2.3 crore female smokers and China with 1.3 crore female smokers, are worse off.

WASHINGTON, Aug. 4 (Xinhua) -- U.S. scientists have found two gene mutations occurring in oligodendrogliomas, the second-most common form of brain cancer, according to a study to be published Friday in journal Science.For years scientists have been looking for the primary cancer genes involved in oligodendrogliomas evolvement. Scientists know the two chromosomes held the probable mutations, but the particular gene information remains unclear.Now scientists at Duke University Medical Center and Johns Hopkins University have discovered the most likely genetic mutations that researchers have been hunting for on chromosomes 1 and 19.The genes they identified, CIC or FUBP1, are tumor suppressor genes. The cancer-related pathways that involve these genes could become targets for future treatments, said Hai Yan, a Duke associate professor of pathology and co-corresponding author of the study.The researchers found CIC on chromosome 19 and FUBP1 on chromosome 1 based on an initial study of seven oligodendrogliomas. They found six mutations and two mutations, respectively, in the seven tumors. Further study of 27 more of these tumors showed that there were 12 and three mutations of CIC and FUBP1, respectively. The two genes were rarely mutated in other types of cancers, indicating that they are oligodendroglioma-specific genes.These genes were difficult to find until the technology improved, said Yan."The team used whole genome sequencing technology so that no genes would be excluded, and we found to our surprise that one gene, on chromosome 19, was mutated in six out of the seven initial tumor specimens we sequenced," Yan said. "A mutation frequency of 85 percent is very high."The finding of two additional new genes involved in oligodendrogliomas increases the chances for an effective combination drug therapy for the tumor, Yan said. He envisions a combination cocktail of drugs similar to the combination-drug treatments taken by HIV patients that would target different pathways involved in cancer, and assist both in reducing the chance of relapsing and increasing odds of success.

NAIROBI, Aug. 18 (Xinhua) -- The World Health Organization (WHO) on Thursday decried increased number of confirmed cholera cases in the Somalian capital Mogadishu, and growing reports of acute watery diarrhea in Kismayo and other crowded urban centers, saying an urgent multi-sector response to contain the spread of this highly contagious disease is being mounted.The UN health agency said has confirmed cholera in Banadir, Bay, Mudug and Lower Shabelle regions and the number of acute watery diarrhea cases has increased dramatically in the last few months.WHO Representative for Somalia Marthe Everard said combination of poor sanitation conditions, a shortage of safe water, overcrowding and high malnutrition rates, creates the perfect combination for infectious diseases, such as cholera and pneumonia, to spread and increase the number of deaths. "For the last few years, a network of health workers reporting to the early warning system is in place, however they report through a health facility or mobile clinic. Yet the large numbers of displaced people in Mogadishu are making it more difficult to record the various diseases," Everard said in a statement issued in Nairobi. "We urgently need more mobile clinics that will provide basic health care services to the many displaced and who will strengthen the reporting on new outbreaks. This is critical to our response and our ability to save lives."According to WHO, about seventy-five percent of all cases of acute watery diarrhea are children under the age of five.Since January this year, 4,272 cases of acute watery diarrhea/ cholera have been reported in Banadir Hospital in Mogadishu alone. However, at this stage most of the cholera cases in the various regions are contained and under control. "Our major concern is to monitor and detect new disease outbreaks in the many informal settlements set up by internally displaced people in and around Mogadishu", says Everard.Although cholera is endemic in the country, the last major cholera outbreak was in 2007 with an estimated 67,000 cases.WHO said recent efforts to cholrinate the water supply of Mogadishu, along with efforts to improve hygiene and sanitation have prevented a serious outbreak but with the large influx of some 100,000 people alone this year into Mogadishu, bringing the total number of IDPs in the capital to an estimated 470,000, many are living in overcrowded settlements, there is an acute shortage of safe water and adequate sanitation. "There is no need for a child to die of diarrhea, yet this is tragic reality for a Somali child, who is acutely malnourished. It is a lethal combination." said Rozanne Chorlton, UNICEF Representative for Somalia. "These types of diseases can be prevented and treated quickly, but to save children's lives we need to make sure safe water, sanitation and hygiene along with early access to primary health care, are an integral part of our emergency response."WHO said partners in the health and water and sanitation sectors are currently preparing for a potential 100,000 cholera cases including 80,000 moderate cases and 20,000 severe cases.Emergency diarrheal disease kits made up of medical supplies such as syringes, infusions, and oral rehydration fluids (ORS), already prepositioned by UNICEF and WHO have been sent to 13 hospitals.An additional 200 diarrheal disease kits, each able to treat 100 severe cases and 400 moderate cases are being procured and should be in Southern Somalia in the next few weeks, it said.In addition, WHO said, the case management of severe dehydration with and without malnutrition is being strengthened and focus is now on mobilizing a network of already trained community health promoters to move from door to door with health hygiene education messages. "Health posts will be stocked with essential medicines and ORS to identify and promptly treat patients. Many of Southern Somalia' s rural areas and urban centers rely on shallow wells, which unless protected or treated with chlorine can serve as the perfect breeding ground for water borne diseases," it said.To respond to this threat and prevent a major outbreak, the UN health agency said partners in the water, sanitation and hygiene sector are scaling up their actions to target 1.5 million people across high risk areas of the south.Supplies of chlorine and essential items for hygiene and household treatment and storage of water are being distributed.Already 217 water sources are being chlorinated and 58 water point outlets benefitting 483,200 residents and internally displaced people in Mogadishu.In addition, household hygiene supplies, including water purification tablets, soap and buckets, enough for 48,000 families, are being distributed at existing feeding centers for malnourished children.Campaigns to educate families about the treatment of drinking water, safe disposal of waste and encourage hand washing with soap will also be scaled up in high risk communities.As part of the updated 2011 UN Consolidated Appeal for Somalia, an estimated 80 million U.S. dollars is needed for the health sector and 78 million dollars is required for the water, sanitation and hygiene sector.So far, each sector has respectively raised 30 percent and 37 percent of the required money.