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For the second and final time during the 2020 presidential race, President Donald Trump and Democratic presidential nominee Joe Biden square off on the debate stage.Current polls show Trump trailing in most national polls by a 6 to 10 percent margin and trailing in three key states that he won in 2016: Pennsylvania, Wisconsin, and Michigan — though Trump did outperform poll numbers during the 2016 election.The debate also comes amid a flood of political news out of Washington that could impact talking points.Republicans on the Senate Judiciary Committee sent Judge Amy Coney Barrett's Supreme Court nomination to the Senate floor — a significant step that could allow the Senate to confirm her nomination as soon as Monday.A day after leaving in the middle of a 60 Minutes interview, the White House scooped CBS and published the full, unedited footage online.Weekly unemployment claims dipped below 800,000 for the first time in months, though those figures remain historically high.Thursday's debate was originally slated to be the third debate between the two candidates. However, a town hall debate that was scheduled to take place on Oct. 15 was canceled after Trump declined to participate. Trump objected to the Commission on Presidential Debates announced the town hall would take place virtually due to the President's COVID-19 diagnosis.Thursday's debate will also feature a format change that requires a candidates' microphone to be turned off while his opponent is delivering his opening remarks during a given topic.Last Friday, moderator Kristen Welker announced that the following topics would be addressed Thursday night: fighting COVID-19, American families, race in America, climate change, national security, and leadership.Watch the debate live in this story beginning at 9 p.m. ET. 1816

Following Emergency Use Authorization by the FDA and a formal recommendation from the Centers for Disease Control and Prevention (CDC) over the weekend, the first Americans began receiving Pfizer's COVID-19 vaccine on Monday.As the sun rose on the east coast, medical professionals began distributing vaccines to patients who had lined up for an initial dose.In New York, Gov. Andrew Cuomo was there to witness the first injection in his state. According to Scripps station WPIX in New York City, the first person to receive the vaccine in the state was Sandra Lindsay, a nurse who works at Long Island Jewish Medical Center.Kentucky Gov. Andy Beshear was also on hand to see the first injections in his commonwealth.At 2:30 p.m. ET in Washington, D.C., Health and Human Services Director Alex Azar and Surgeon General Jerome Adams will be on hand to witness as health care workers at George Washington University Hospital will be among the first to receive the vaccine.The first injections of the vaccine came the same day that the U.S. is expected to surpass 300,000 COVID-19 deaths. As of Monday morning, Johns Hopkins reports that the U.S. had total 299,000 deaths; the country has seen more than 2,000 deaths a day in recent weeks.On Friday night, the FDA made the much-anticipated move to approve Pfizer's COVID-19 vaccine candidate for Emergency Use. The move allows the U.S. to begin inoculating Americans against COVID-19, which is currently spreading and killing at rates not yet seen during the pandemic.The FDA prompted Pfizer to begin shipping the first doses of the vaccine nationwide. On Sunday, the CDC issued a recommendation for the vaccine, giving health care professionals to start distributing shots to those that want them.Pfizer's vaccine requires two doses, which need to be taken 21 days apart. Everyone who receives an initial dose on Monday will need to return next month to complete the process.Pfizer's development of a COVID-19 vaccine — which studies have shown to be 95% effective in preventing the virus — in under a year is nothing short of a medical miracle. The previous speed record for vaccine development occurred in the 1960s when researchers developed a vaccine for the mumps in just four years.However, plenty of obstacles remain for the U.S. amid the pandemic. Anywhere from about 30% to 50% of Americans have expressed skepticism in getting a COVID-19. Health care experts suspect that about 70% of Americans would need COVID-19 antibodies in order to reach herd immunity.A COVID-19 vaccine developed by Moderna is expected to be granted Emergency Use Authorization later this week, and health care professionals could begin distributing that vaccine as soon as next week.An earlier version of this story mistakenly stated that the two doses of Pfizer's vaccine needed to be taken 28 days apart. 2847

Former FBI Director James Comey warned that if President Donald Trump ever tries to fire special counsel Robert Mueller, then it would be the President's "most serious attack yet on the rule of law," and said that "it's possible" the Russians could have information on Trump that could be used to compromise him.Comey also said Trump is "morally unfit to be president" and claimed there is "certainly some evidence of obstruction of justice" by Trump.The comments came during a wide-ranging, exclusive interview with ABC News chief anchor George Stephanopoulos. The media appearance is the first time Comey has sat for a televised interview since Trump fired him last year. It also kicks off a promotional tour that the former FBI director is embarking on to promote the release of his new book, "A Higher Loyalty." 823

Former Trump campaign aide Sam Nunberg arrived at District Court in Washington, DC, Friday morning, where he is expected to deliver federal grand jury testimony as part of special counsel Robert Mueller's investigation.Nunberg is the first recognizable Trump campaign affiliate to appear at a hearing related to Mueller's investigation into Russian meddling in the 2016 election by walking through the main entrance of the federal courthouse and heading to the grand jury area. Other witnesses have presumably testified before Mueller's grand jury since it started meeting last July, but none have made as public an appearance.  641

Five people died when a small plane crashed in a Southern California parking lot on Sunday, according to the Orange County Fire Authority.The twin-engine Cessna plane crashed in Santa Ana, and had been bound to John Wayne Airport in Orange County, said Capt. Tony Bommarito, the public information officer with Orange County Fire Authority.There were no survivors on the airplane, he said.The plane crashed just a block away from South Coast Plaza, a large mall. There were no injuries on the ground. The plane hit an unoccupied, parked vehicle on the ground, but the owner was in a store at the time of the crash, Bommarito said. 638

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