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A new study suggests misguided antibodies created as a response when someone is infected with the coronavirus could be the cause behind both more severe COVID-19 symptoms and those who report having symptoms for months after initially recovering.Researchers at Yale University found that COVID-19 patients they studied had high levels of antibodies that had turned on them; these wayward antibodies blocked antiviral defenses, wiped out helpful immune cells and attacked the body in several areas including the brain, blood vessels, liver and gastrointestinal tract.“Covid-19 patients make autoantibodies that actually interfere with immune responses against the virus,” Aaron Ring, an immunobiologist at Yale and senior author on the study, told The Guardian.Autoantibodies are antibodies that attack the body’s own proteins by mistake and disrupt their normal functions.“We certainly believe that these autoantibodies are harmful to patients with Covid-19,” said Ring. He added that the harmful effects of these autoantibodies could continue well after the initial infection has been overcome. He said antibodies can last for a long time, and if they are misguided in their attacks, the effects of their attacks on the body could also last a while.The study, which has yet to be peer reviewed and formally published, looked at antibodies from 194 COVID-19 patients and hospital workers with a range of symptoms and severity of symptoms.Other conditions, like lupus, multiple sclerosis and rheumatoid arthritis, are also made worse by the immune system malfunctioning and attacking the body. 1600

A US advisory panel has released their recommendations on how a future COVID-19 vaccine should be distributed, and is now seeking public comments on their draft plan.The National Academies of Science, Engineering and Medicine published their discussion draft Tuesday afternoon on their website. It is meant to “assist policymakers in planning for equitable allocation of a vaccine against COVID-19.”The draft plan has a four-phased approach to handle the intense demand for and limited supply of the vaccine when it is first developed.“While major efforts are being made to have a significant supply of COVID-19 vaccine as soon as possible, the committee has been tasked with considering the tough choices that will need to be made for allocating the tightly constrained initial supplies,” said committee co-chair Helene Gayle, president and CEO of the Chicago Community TrustThe plan states in the first phase “would be ‘frontline’ health workers—health professionals who are involved in direct patient care, as well as those in transport, environmental services staff, or other health care facility services, who risk exposure to bodily fluids or aerosols. Under conditions of such scarcity, access should not be defined by professional title, but rather by the individual’s actual risk of exposure to COVID-19.”Their plan also gives higher priority to older Americans living in group settings. They cite data showing about 80 percent of all COVID-19 deaths in the US occurred in people over the age of 65, and a significant proportion of them were people living in long-term care facilities.“Recognizing the importance of education and child development,” tier 2 includes teachers and school staff, as well as those with pre-existing conditions that put them at a heightened risk of severe complications from COVID-19 and those living in group housing situations not included in tier 1.The group states that by the time there is enough of the vaccine to reach tier 4, “ideally, these individuals would be willing to participate in an egalitarian process (such as a lottery) if there are persistent local or regional shortages in this phase.”The group that developed this draft was formed in July at the request of the National Institutes of Health and the Centers for Disease Control and Prevention.“We are pleased to help inform the government’s decision-making process and provide our expert advice for priority-setting for the equitable allocation of potential COVID-19 vaccines,” said National Academy of Medicine President Victor J. Dzau. “Input from the public on this draft framework, especially from communities disproportionately affected by COVID-19, is essential to produce a final report that is objective, balanced, and inclusive.”The public comment period will be open until 11:59 p.m. on Friday, September 4. Commenters will be able to download and review the draft before submitting a comment at nationalacademies.org/VaccineAllocationComment.A final recommendation will be published this fall to include any changes following public comment. 3069

A Rikers Island inmate is back in police custody in New York after attempting to escape on Thursday, officials said.Around 12:30 p.m., the detainee climbed a recreation yard fence and ran to the shoreline, Deputy Commissioner of Public Information Peter Thorne said.The detainee was apprehended by K-9 Correction Officers Larry McCardle and Gregory Braska, Correction Officers' Benevolent Association President Elias Husamudeen said."These two brave officers immediately jumped into action to bring the inmate back into custody without any regards for their own safety," Husamudeen said. "We proudly salute them for their bravery and for reminding the public the critical role Correction Officers play every day in maintaining public safety.”Husamudeen is scheduled to speak Thursday afternoon.This is a developing story. Check back for updates.WPIX's Aliza Chasan was first to report this story. 904

A standing-room only pit ticket to one of Taylor Swift’s June concerts at Soldier Field in Chicago could cost you 5. Some would say that’s a high price to pay to see songs from “Reputation” performed live.Before you drop a few hundred (or thousand) dollars on concert tickets, here are seven ways to save money on a live show. While every tip won’t apply to every show, you can use this list to find the strategies that will work for you. 459

A University of Michigan student says he got stuck with nightmare roommates. He says they urinated in his dog’s water bowl, destroyed his property, and then he felt they tormented him after he came out as gay.Thursday he asked a judge to force one to stay away from him.Matthew Mansour says he leased a student apartment through the company Landmark. They rent apartments like dorms - so he got three roommates he didn’t know. 434

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