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INDIANAPOLIS — The U.S. Food and Drug Administration on Monday granted emergency use authorization to Eli Lilly and Company's experimental COVID-19 antibody treatment bamlanivimab.According to a statement from the company, the drug is authorized for the treatment of mild to moderate COVID-19 in adults and pediatric patients 12 years and older with a positive COVID-19 test who are at high risk for progressing to severe COVID-19 and/or hospitalization. Lilly said in a statement the drug should be administered as soon as possible after a positive COVID-19 test and within 10 days of symptom onset. The authorization allows for the distribution and emergency use of bamlanivimab, which is administered via a single intravenous infusion."This emergency authorization allows us to make bamlanivimab available as a COVID-19 treatment for recently diagnosed, high-risk patients — adding a valuable tool for doctors fighting the now-increasing burden of this global pandemic," David A. Ricks, Lilly's chairman and CEO, said. "The rapid development and availability of bamlanivimab could not have been achieved without the relentless work of our Lilly team, collaboration across the industry and the urgent work being done by the government to ensure appropriate allocation to patients who need it the most."The emergency use authorization is based on data from BLAZE-1, a randomized, double-blind, placebo-controlled Phase 2 study in patients with recently diagnosed mild to moderate COVID-19 in the outpatient setting. Patients treated with the drug showed reduced viral load and rates of symptoms and hospitalization, Lilly said in the statement. Infusion reactions and other allergic hypersensitivity events have been reported, Lilly said. The emergency use authorization includes a warning for hypersensitivity including anaphylaxis and infusion-related reactions.Lilly said the drug is not authorized for use in patients who are hospitalized due to COVID-19 or who require oxygen therapy due to COVID-19 or who require an increase in baseline oxygen flow rate due to COVID-19 in those on chronic oxygen therapy due to underlying non-COVID-19 related comorbidity."The BLAZE-1 data show bamlanivimab, when given early in the disease course, may help patients clear the virus and reduce COVID-related hospitalizations, supporting our belief that neutralizing antibodies can be an important therapeutic option for patients fighting this virus," Daniel Skovronsky, M.D., Ph.D., Lilly's chief scientific officer and president of Lilly Research Laboratories, said. "We're proud of the speed with which we have been able to bring patients this therapy specifically designed to treat COVID-19. We thank those who have contributed to this medical advancement, particularly the clinical trial investigators and participants around the country." This article was written by Bob Blake for WRTV. 2906

A major warning from scientists around the world: Do not depend on antibodies for permanent immunity from COVID-19. This comes on the heels of several studies showing that antibodies only last in our bodies for about two to three months.“That’s normal,” said Dr. Michael Teng, a professor at the University of South Florida's College of Internal Medicine and a researcher.According to Dr. Teng, our immune system creates antibodies when a virus enters our bodies. Their main purpose is to stop the virus from getting into our cells. Having few or no antibodies isn’t necessarily a bad thing, and it doesn’t mean you’ll be reinfected with the virus right away.“Antibodies are supposed to go down after a while,” Dr. Teng said. “You’re not supposed to have high elevated levels of antibodies for weeks on end. It’s not normal.”Scientists were hoping the antibodies produced from COVID-19 would stick around as long as antibodies produced from other forms of coronavirus, like SARS. Now that studies have shown that they don’t, they say we should rely on treatment, and working to come up with a vaccine.There are several potential vaccines being tested right now, but don’t expect to get your hands on one any time soon.“The fastest vaccine that we ever made was the Mumps vaccine and that took four years,” said Dr. Teng. WFTS' JJ Burton first reported this story. 1386

Dr. Scott Turner does his best to treat patients with memory disorders such as dementia. While there are treatments that may temporarily help, there's no cure for dementia, which is why a new study is getting a lot of attention. The study found your daily dose of certain medications could be increasing your risk for developing dementia. “It's a pretty substantial risk and just brings to bear the thought these medications should not be used lightly,” Dr. Turner with Georgetown University Medical Center, says. The study--published in the Journal of the American Medical Association--found the risk of getting dementia increased nearly 50 percent for patients who took medication every day for at least three years to treat some of the most common conditions in older adults, including bladder control, Parkinson’s, depression and epilepsy. “This study's important because dementia is very common in older individuals, and these classes of medications are also commonly prescribed,” Dr. Turner expresses. “So, I think there will be a lot of discussions between patients and their doctors about the risks and benefits of these medications.” The study warns people not to stop taking any medication without speaking with their doctor. Alzheimer's is the most common type of dementia, which is the sixth leading cause of death in the United States. 1363

Chicago White Sox manager Ricky Renteria will not be coaching against Cleveland tonight after waking up with a cough and nasal congestion.The team says Renteria underwent a COVID-19 test at a Cleveland hospital on Monday. He will not manage until he gets the results.The Indians are scheduled to start a home series against the White Sox Monday evening.This all comes on the heels of at least 14 Miami Marlins players, employees and coaches testing positive for the virus. The Marlins and the Philadelphia Phillies have canceled their game tonight due to the number of Marlins who tested positive. RELATED: Marlins, Phillies cancel games amid COVID-19 outbreak fears This article was written by Courtney Shaw for WEWS. 741

A baby male giraffe was born last week at Busch Gardens Tampa Bay!The park says Bea, a 14-year old reticulated giraffe, delivered her third calf on June 19. The Busch Gardens zoological team has been monitoring Bea and her male calf as they continue to bond behind the scenes at the park. As important developmental milestones are reached over the next few months, Bea and her calf will soon join the herd on the park’s Serengeti Plain where they can be spotted by guests.WFTS' Zack Perry was the first to report this story. 544