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SANTO DOMINGO, Jan. 11 (Xinhua) -- The Dominican Republic and Haiti Wednesday launched a joint plan aimed at eliminating cholera, which has claimed more than 7,000 lives in both countries since October 2010.The efforts were backed by the World Health Organization (WHO), the Pan American Health Organization (PAHO), and the United Nations International Children's Emergency Fund (UNICEF), Dominican officials said.The plan, "Call to action: the Hispaniola without cholera", aims to improve sanitary and living conditions of the Haiti people who face herculean reconstruction work following a devastating earthquake in the country on Jan. 12, 2010, that killed 220,000 people and displaced over 1 million.Cases of cholera, an infection that causes severe diarrhea that can lead to dehydration and death, first appeared in Haiti in October, 2010.The epidemic has so far killed more than 7,000 people and left nearly 500,000 more sick in Haiti.It also killed 135 people in the Dominican Republic as of September 2011, according to Dominican health authorities.Some 500 million U.S. dollars will be invested in projects related to sanitization and the construction of infrastructure that has to do with waterworks in both nations in the long term.

WASHINGTON, Oct. 13 (Xinhua) -- U.S. researchers have corrected sickle cell disease in adult laboratory mice that had been bred to have the inherited blood disorder by activating production of a special blood component, according to a study published online Thursday in the journal Science.Sickle cell disease results from an abnormality in hemoglobin, the protein found in red blood cells that is responsible for transporting oxygen throughout the body. People living with sickle cell disease have two copies of an altered gene that produces sickle hemoglobin instead of normal adult hemoglobin. Sickle hemoglobin changes shape after releasing its oxygen, causing the red blood cell to become stiff, misshapen and sticky, and slowing blood flow to tissues. This process damages organs and causes pain.The study tested a new approach to increasing the production of a third form of hemoglobin -- fetal hemoglobin. Production of fetal hemoglobin predominates before birth, but turns off thereafter as adult hemoglobin production takes over. People with sickle cell disease are unable to make normal adult hemoglobin, and instead make sickle hemoglobin starting in infancy.An elevated level of fetal hemoglobin within the red blood cell reduces the tendency of sickle hemoglobin to change the shape of red blood cells. Considerable research has shown that the drug hydroxyurea increases production of fetal hemoglobin and reduces the number of pain crises and other complications of sickle cell disease in adults and children. However, not all patients respond well to hydroxyurea, and adverse side effects are a concern.The current study explores a more targeted approach to increasing fetal hemoglobin production. It builds upon earlier studies that discovered a protein called BCL11A normally suppresses the production of fetal hemoglobin soon after birth. The researchers viewed the BCL11A protein as a target for therapy and decided to see what would happen if they blocked production of the protein.The paper details how the research team silenced the mouse gene that produces the BCL11A protein in mice with sickle cell disease. Silencing the gene turned off production of the BCL11A protein and allowed the adult mice to continue to produce fetal hemoglobin. It appears to have eliminated disease symptoms without affecting other aspects of blood production."This discovery provides an important new target for future therapies in people with sickle cell disease," said Susan Shurin, acting director of the U.S. National Heart, Lung, and Blood Institute, which co-funded the study. "More work is needed before it will be possible to test such therapies in people, but this study demonstrates that the approach works in principle."Approximately 100,000 Americans live with sickle cell disease. It is most prevalent in people of African, Hispanic, Mediterranean, and Middle Eastern descent. There is no widely available cure for sickle cell disease. Bone marrow transplants have cured some patients, but the treatment is not without risk and most patients do not have relatives who can donate compatible and healthy bone marrow to them.

TAIPEI, Dec. 10 (Xinhua) -- A televised debate among three candidates for Taiwan's next deputy leader was staged Saturday, highlighting cross-Strait political and economic issues, for next month's Taiwan leader election.The three candidates touched upon topics such as stances on the reunification of Taiwan and the Chinese mainland and the "Taiwan independence," last year's signing of the cross-Strait Economic Cooperation Framework Agreement (ECFA), among other cross-Strait issues, during the second face-to-face debate before the Jan. 14, 2012 election.Wu Den-yih, who is incumbent Taiwanese leader Ma Ying-jeou's running mate and currently chief of Taiwan's executive authority, said the signing of the ECFA aims to "help people do business and enhance Taiwan's competitiveness." Ma is seeking a second term.The ECFA did not speed up Taiwan's inclination toward the mainland market, but ensured the island's utmost interests instead, Wu said, adding that if Ma, who is also chairman of Taiwan's ruling Kuomintang (KMT) party, did not win during the upcoming election, cross-Strait peace and stability would not be maintained.However, Wu's main rival Su Jia-chyuan, the running mate of Tsai Ing-wen who campaigned for Taiwan's next leader representing major opposition Democratic Progressive Party (DPP), claimed that Taiwan is a "sovereign state" and its fate would be decided by Taiwanese themselves, no matter it would become independent or unified with the mainland, or maintain the status quo.Taiwan's future would be guaranteed only if the so-called "Taiwan consensus," put forward by Tsai, was realized, Su said during the debate.Another debater, Lin Ruey-shiung, 72, the running mate of People First Party (PFP) candidate James Soong, called for the signing of a cross-Strait peace accord, and said that the Chinese nation was fundamentally one family, with reunification benefiting both and secession hurting both.Lin said, as a member of the Chinese nation, Taiwan must be reunified with the mainland in the future, without wars, and it is the aspiration of all Taiwanese that people of both sides could freely visit each other.The three candidates also debated on anti-corruption, financial deficit and social equity.Saturday's debate among the candidates for deputy leader was the second of a three-part series. A debate of the Taiwan leader hopefuls was staged last Saturday, and they will spar again on Dec. 17.

JAKARTA, Oct. 6 (Xinhua) -- United Nations Children's Fund (UNICEF) representative for Indonesia Angela Kearney said on Thursday that Indonesia's infant mortality rate is still high although it showed a downward trend in the past few years, local media reported.Based on a UNICEF global child mortality report, over the past 10 years infant mortality rate declined significantly to 35 out of every 1,000 births in 2011 from 97 out of every 1,000 births in 1991, she said at workshop on household to hospital cantinuum care held in Makassar, South Sulawesi.The achievement was inseparable from the central and regional government's endeavors, she said.After all, the results of a health demography survey showed 193, 000 children lost life chance every year before they reached the age of 5 years, she said.In South Sulawesi alone, 17.3 out of every 1,000 newborns died before they reached the age of 28 days last year. Two-thirds of the deaths occurred on the first week of their life and one out of every four mothers gave birth to their children without the help of trained medical workers.Mothers' poor access to health facilities in the country posed one of the obstacles to the promotion of the nation's health. One out of every five mothers came from poor families, she said.She said that a lack of infrastructures and equipment and the low number of trained medical workers had hindered the fulfillment of health services, the Antara news service said.To deal with the challenge, the method of providing health services must be improved and the support of trained medical workers must be increased, she said."I am very happy to see UNICEF cooperating with the South Sulawesi provincial government to develop comprehensive approaches to overcome the shortcomings at social level and public health system at provincial health facilities," she said.

SAN FRANCISCO, Oct. 10 (Xinhua) -- Apple announced on Monday that pre-orders of its iPhone 4S have topped 1 million in a single day, surpassing the previous single-day pre-order record of the company's smartphone.The iPhone 4S pre-orders surpassed 1 million in the first 24 hours and the previous single day pre-order record held by iPhone 4 is 600,000, according to Apple."We are blown away with the incredible customer response to iPhone 4S," Philip Schiller, Apple's senior vice president of worldwide product marketing, said in a statement."The first day pre-orders for iPhone 4S have been the most for any new product that Apple has ever launched and we are thrilled that customers love iPhone 4S as much as we do," he added.U.S., newly installed Chief Executive Officer Tim Cook takes stage to give a general introduction of Apple's products, Oct. 4, 2011. Apple Inc. last Tuesday unveils iPhone 4S, the much-anticipated latest generation of iPhone.The iPhone 4S, which looks the same as the iPhone 4 but has major hardware upgrade inside, is available for pre-order last Friday and set to first arrive in stores in the United States this Friday.So far, iPhone 4, which, according to Apple, has been sold more than the first three generations of iPhones combined, is Apple's best selling iPhone.The pre-order numbers are good news for Apple as the initial introduction of iPhone 4S last Tuesday has not lived up to the anticipation of some investors and analysts, and spurred a new wave of concerns about whether the company could keep its innovation momentum in the wake of the passing of its co-founder Steve Jobs last Wednesday.