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SAN DIEGO (KGTV) — In some of the most severe cases of COVID-19, doctors are finding it’s not the coronavirus making people critically ill.It’s their own immune system, and a San Diego-based biotech company thinks it has an answer.La Jolla-based INmune Bio announced Tuesday it has FDA approval to begin a Phase 2 clinical trial on its inflammation fighting drug, Quellor.In many of the sickest COVID patients, doctors have noticed their blood is filled with high levels of immune proteins called cytokines. Cytokines act as messengers between cells and the virus can cause them to go haywire, setting off what’s known as a cytokine storm.In a cytokine storm, the body’s immune system starts to attack its own cells and tissues rather than the virus. During the Spanish Flu of 1918, many of the deaths were caused by cytokine storms.“You need to control the cytokine storm to keep patients from getting sick,” said INmune Bio’s CEO Dr. R.J. Tesi.There are several different types of cytokines. A drug undergoing testing in a federal trial with remdesivir targets a cytokine called beta interferon.The San Diego biotech’s drug Quellor suppresses a very specific cytokine called soluble tumor necrosis factor, which Dr. Tesi calls “the master cytokine” because of its role in triggering other immune proteins.Dr. Tesi said this particular cytokine may contribute to another troubling issue with COVID-19: blood clotting.“When they write the history of COVID-19, the clots are going to be the bad guy,” Dr. Tesi said. “These blood clots go off everywhere and they gum up the works. They make it so the lungs can't work. They make it so the kidneys can't work. They make it so the heart is screwed up. Make it so you have strokes.”INmune Bio, which is publicly traded but has just six full-time employees, is hoping its drug can address both the blood clots and the inflammation.The company plans to enroll 366 hospitalized COVID-19 patients for a Phase 2 trial to see if intervention with Quellor can keep people off ventilators and out of the ICU. 2053

SAN DIEGO (KGTV) -- Just in time for the Fourth of July, the Mission Beach Plunge pool is reopening to the public. The iconic pool was one of the original attractions when the amusement park opened in 1925. However, it had run into hard times in recent years and has been closed for much of the last decade. One management company went bankrupt. The next came up with a renovation plan, only to discover dangerous, corroding conditions inside, leading to the pool's closure in 2014.Thanks to a partnership between the City of San Diego, Fit Athletic, and Pacifica Enterprises, the renovated pool is almost unrecognizable. "This is absolutely special, incredible," said Dr. McQuary, a longtime San Diego resident who is active in the community."What I remember about the Plunge was the issues and concerns about how we can swim and still be safe. When things would fall from the sky, it wasn't rain; it was the plaster from the ceiling!"The Plunge at Fit features floor to wall glass ceilings and a retractable roof. It also incorporates some of the building's original features, replicating the tiling and original archways.Part of the new Fit Athletic Mission Beach gym, the facility also offers beach views throughout. "It's been part of the San Diego landscape and part of the lifestyle for all those years," said Terry Curren, who moved to Mission Beach in 1937.The Plunge will officially open to the public on July 4; day passes start at a day, and there are also membership options available. 1511

SAN DIEGO (KGTV) — In San Diego Comic-Con's first foray as an online-only event, fans experienced some benefits and pitfalls of a virtual convention.While fans had arguably the most access to Comic-Con content ever, there were still some aspects that couldn't be recreated digitally. At the same time, that's all right. Fans afraid there would be no convention whatsoever still got to enjoy the annual pop-culture celebration.With that said, there are some things fans may like to see again even at an in-person convention — or hope to avoid.RELATED:Videos and Special FX: Perks of San Diego Comic-Con going virtualPHOTOS: Best cosplay from San Diego Comic-ConSan Diego's hospitality industry suffers from Comic-Con@HomeWhat worked: PanelsFor the first time in Comic-Con history, every attendee had the opportunity to see any of SDCC's hundreds of panels. No waiting in Hall H's line. No attending an earlier panel to save a seat for a later event. Every panel was streamed on Comic-Con's website and most were made available on YouTube afterward for fans to catch. Exclusive content aired during panels also made their way onto the internet arguably faster than previous years. While the glitz of seeing stars, artists, and writers in person was missing, the heart of enjoying a panel for its presentation was still there.What didn't: ExclusivesAdmittedly, Comic-Con isn't just about exclusive merchandise. But many attendees enjoy being able to score gear that you'll only get at SDCC — for resale or to keep. However, when it came to exclusives, internet connection and website servers were at the will of how many people logged onto their site. So when something was highly sought after, websites saw a lot of traffic — sometimes too much. In the case of several popular merchandisers — like Funko, Mondo, or Hasbro — exclusives often sold out quickly, sometimes before the convention even occurred. What worked: "Off-site" experiencesOff-site experiences outside the convention center have become as much of Comic-Con as the exhibit hall inside the center. With the convention online, some exhibitors took the opportunity to host some unique games and activities on their own websites. FX Unlocked showcased its lineup of FX shows with games, trivia, and digital extras, while Amazon held its own virtual con to showcase its products and Amazon Prime shows. FutureTechLive! also put together a virtual World Builders activation for users to unleash their imagination.What didn't: CosplayOne of the best parts of Comic-Con is seeing everyone dressed up as their favorite characters waltzing around downtown San Diego. Where else can you run into Kirk and Spock or Batman enjoying a bite to eat in broad daylight? While the convention did its best to showcase cosplayers online with a "masquerade ball" via Tumblr, it just isn't quite the same as being at the event in-person. What worked: Connecting with fansHosting Comic-Con online ensured fans can connect with their favorite comic book writers, artists, and even entertainers. Without having to manage a tight schedule of going location to location for panels and events, users could simply log on and watch a panel, win some free swag in some cases, or reach out to comic book writers and artists for commissions or to purchase their work. No walking through a packed Artist Alley or standing in line for a free t-shirt — though some may argue that's part of the appeal.What didn't: Recreating being thereSDCC made several activities available online ahead of the convention, like signs and badges to print out to dress your home for the event. A virtual exhibit floor was also offered online and while fun, was a bit tricky to navigate on your phone. Though it was great to offer those activities for fans, nothing can really recreate that feeling of walking through the halls of the convention center or visiting your favorite comic book artists. 3915

SAN DIEGO (KGTV) -- Local, independently owned grocery stores are keeping an eye on a potential grocery worker strike in Southern California. On Monday, UFCW Local 135 will vote to authorize strikes at Albertsons, Vons and Ralphs. Union representatives say employees have been working without a contract since March. Union president, Todd Walters, says they've met 17 times with the companies asking for better wages, health benefits and pensions. In South Park, the owner of a small grocery store says he hopes the bigger retailers don't enter a strike. David Halabo owns Food Bowl Market with his wife. During the last strike in 2003, Halabo says his business saw an increase in customers for specific items like bread, milk and eggs. Halabo says he's keeping an eye on the negotiations, but says he'll only stock up on extra items if the workers do go on strike. The small business owner says, although is business would benefit, he doesn't want to see a strike happen.Ralphs spokesperson John Votava sent 10News a statement from the company, saying:"We are negotiating in good faith with the union for a fair and balanced contract that is good for our associates, as well as our company. As you know, negotiations are about finding compromise, and this can take time. Throughout the negotiations, it's business as usual in our stores and Ralphs is extremely proud of our associates who remain focused on serving our customers, communities and each other."Vons/Albertson's spokesperson Melissa Hill sent this statement as well, saying:"We are committed to working collaboratively with the unions to ensure that we reach an agreement that is fair to our employees, good for our customers and allows Albertsons, Vons, and Pavilions to remain competitive in the Southern California market. We feel the strike authorization vote is premature and will cause our employees and customers undue concern; nevertheless, we will be back at the bargaining table on July 10 and hope to reach an agreement soon."The vote doesn't mean employees will go on strike immediately, but it does give the union the ability to call for one at any time. Grocery workers will have three opportunities to vote on Monday, at 9 a.m., 1:00 p.m. and 6 p.m. 2237

SAN DIEGO (KGTV) -- It's almost time for back to school and that means it's time to go shopping and gather all those essentials. While some items may be obvious on your shopping list, others are more obscure. We've compiled a list of back to school tech as you prepare to make that back to school shopping list. Check out the items below for more: Livescribe – 3.5 stars on AmazonThis nifty little gadget will come in handy for those long, note-taking days. With Livescribe, you can record everything you write and hear so you don’t miss a thing, according to Amazon. Then, replay your meetings or lectures simply by tapping on your notes. Native Union Key Cable – 5 stars on AmazonAlways losing that phone charger? The Native Union Key Cable attaches to your keychain so you never have that problem again (unless you can’t find your keys, of course.) The charger is compatible with most devices, according to Amazon. Casio Touchscreen with Stylus Graphing Calculator – 4 stars on AmazonTime for upper-level math classes? This graphing calculator has a 4.8 inch touchscreen with a stylus. The calculator also has an advanced computer algebra system for all those tough-to-solve math problems. iHome IBT29 Bluetooth alarm clock – 4 stars on AmazonDoes your student have a hard time waking up? The iHome Bluetooth dual alarm clock radio with speakerphone may be the solution (and it changes colors, which is just cool.) The alarm can be set to Bluetooth audio, FM radio or built-in tone. Pixie (4-pack) – 3 stars on AmazonDoes your student lose things often (who doesn’t?) The Pixie shows you at a glance the exact distance in feet and inches to the lost item, according to Amazon. Click here to scroll through a slideshow of the items listed above. 1756