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Researchers published what they say is the first case of a living person diagnosed with the degenerative brain disease chronic traumatic encephalopathy or CTE.While unnamed in the study, lead author Dr. Bennet Omalu confirmed to CNN that the subject of the case was former NFL player Fred McNeill -- who died in 2015.Omalu is credited with first discovering CTE in professional football players. Until now, the only way to diagnose the disease is with a brain exam after death.The diagnosis was first made using an experimental brain scan that can trace a signature protein of CTE called tau. The authors then confirmed the diagnosis with an autopsy. The case study was published in the journal Neurosurgery this week.'It looked like just depression'Omalu first presented these findings exclusively to CNN's chief medical correspondent, Dr. Sanjay Gupta, in 2016. McNeill's wife, Tia, and his two sons, Gavin and Fred Jr., told Gupta then that they saw Fred transform from a fun loving family man at the center of their lives into a man who was dealing with symptoms of memory loss, anger and depression that tore their family apart."There are some times where the father is the stronghold in the family, or the anchor. If you lose that, everything kind of falls apart. That's kind of what happened for us. It looked like financial issues at first; it looked like marital issues, and they separated; then it looked like just depression," Gavin told Gupta.CTE is known for plaguing people with Alzheimer's like symptoms such as memory loss, rage, mood swings, and in some cases, suicidal ideation.Severity of the disease is categorized into four stages, with stage 4 being the most severe. While researchers don't know exactly why certain people develop the disease and others don't, they believe that it results from repeated blows to the head that trigger a build up of tau proteins in the brain.CTE has been called football's "concussion crisis," however experts point out that CTE can develop from any repeated head injury. According to the Boston University CTE Center, "this trauma includes both concussions that cause symptoms and subconcussive hits to the head that cause no symptoms." These subconcussive hits can include the repeated trauma the brain experiences from constant plays, hitting the turf, and tackling. Wrestlers, boxers, and military troops have also been diagnosed with the disease.Seeing CTEWhile McNeill is the first case to be confirmed with an autopsy, the experimental technology has been used on at least a dozen other former NFL players, including Pro Football Hall of Famer, Dallas Cowboy Tony Dorsett. Omalu helped develop and is invested in the diagnostic exam, which uses a radioactive "tracer" called FDDNP to bind to tau proteins in the brain. The tau proteins can then be seen on a PET scan of the brain.Critics have said the protein also can highlight another protein called amyloid, which may be indicative of Alzheimer's or other forms of dementia. But Omalu noted that in CTE, tau makes distinctive patterns in the brain. It has a "specific topographic signature," he said, and that pattern can be detected in imaging.Omalu said he and his team are currently raising money to start a phase 3 clinical trial to further test the technology and replicate what they have seen in McNeill. He anticipates that once funds are raised, it will take another two to three years for the trial and then another year, at least, for approval from the US Food and Drug Administration. When asked, how soon a commercial test could be available, Omalu predicted it could be as soon as a few years. "We are looking at less than five years," he said. 3711
President Donald Trump told special counsel Robert Mueller in writing that Roger Stone did not tell him about WikiLeaks, nor was he told about the 2016 Trump Tower meeting between his son, campaign officials and a Russian lawyer promising dirt on Hillary Clinton, according to two sources familiar with the matter.One source described the President's answers without providing any direct quotes and said the President made clear he was answering to the best of his recollection.This is the first insight into how the President responded to the Mueller team's written questions -- a key unknown as Mueller aims to wrap up his investigation and prepare his final report.These two points -- WikiLeaks and the Trump Tower meeting -- are critical to Mueller's central mission: investigating whether the Trump campaign colluded with Russians during the 2016 campaign.The President's lawyers previously told CNN the answers would match his public statements. Still, these written answers could be subject to criminal charges if false.A spokesman for the special counsel declined to comment. CNN did not get a full readout of all of the President's answers to Mueller's questions.According to many lawyers who have experience in cases such as this, adding the caveat that he has no recollection, as the President apparently did with these written answers to Mueller, is standard procedure as a way to try to shield a client should their recollections be challenged."It's well-documented how frequently he says or tweets false things, and there's no criminal exposure for that," said CNN legal analyst Carrie Cordero. "The difference is, if he lies in his statement to federal investigators, he is potentially exposing himself to criminal liability, assuming he attested to the accuracy of the information."On WikiLeaks, Mueller's team has been investigating whether Stone, a Republican political operative and longtime Trump ally, knew in advance about WikiLeaks' dumps of hacked emails from the Democratic National Committee and Clinton's campaign chairman John Podesta at key times during the 2016 campaign.Investigators have questioned multiple Stone associates in the past few months. Stone has denied having any advance knowledge of WikiLeaks releases."I never discussed any of this with Donald Trump. It's one of the questions that Mr. Mueller wants the President to answer -- one of the written questions. I'm highly confident that his answer will be that he knew nothing about it. We just never discussed it," Stone recently told CNN.Stone's denial matches with what Trump told Mueller: that the two never spoke about WikiLeaks.Trump vehemently denies colluding with Russia. He told The Associated Press in an interview last year, "When WikiLeaks came out ... never heard of WikiLeaks, never heard of it. When WikiLeaks came out, all I was just saying is, 'Well, look at all this information here, this is pretty good stuff.'"On the 2016 Trump Tower meeting, the President has publicly said he didn't know about the meeting."I did NOT know of the meeting with my son, Don Jr," Trump tweeted in July.The President's son told lawmakers he did not tell his father about the meeting in advance. He said he took the meeting to listen to what the Russians had to offer on Clinton.Before the answers were submitted, Mueller had asked Trump's lawyers for call logs and visitor logs related to Stone from Trump Tower, CNN reported earlier this month. The request this late in the investigation surprised Trump's legal team.Stone told CNN he has not been contacted by Mueller's team. Trump Jr. testified under oath to several congressional committees and provided documents to Mueller's investigators. His lawyer has declined to comment on whether Trump Jr. was interviewed by the special counsel. 3795

President Donald Trump's moves on the Deferred Action for Childhood Arrivals program found an unlikely defender Wednesday night: former President Jimmy Carter.The Democratic former commander in chief told town hall attendees at Emory University to "give him credit" for not doing away with the deferred action program completely."To give Trump some due, he hasn't ended DACA yet," Carter said. "What he's said is he has given Congress six months to address the issue, which is long overdue.""It's very difficult because when (President Barack) Obama had a Democratic House and Senate, he didn't do it," he added, pointing to a long history of failed -- and often bipartisan -- efforts to pass comprehensive immigration reform.Carter suggested that a highly publicized six-month ultimatum might be what's needed to spur Congress to action."I don't think it's a hopeless case. I think the pressure and the publicity that Trump has brought to the immigration issue may have stimulated both Democrats and Republicans in the House and Senate to be more accommodating in this longstanding argument," he said.Carter's comments happened before reports emerged from a Wednesday evening meeting at the White House, at which it appeared that the President and Democratic leaders were moving closer to a deal to protect the hundreds of thousands of undocumented immigrants brought to the US as minors. However, the parameters of such a deal -- including whether it will include pathway to citizenship or funding for a border wall -- remain unclear. Although Trump asserted numerous times Thursday that House Speaker Paul Ryan and Senate Majority Leader Mitch McConnell are "very much on board" with his plans, Republicans on Capitol Hill maintain that there has been "no agreement."Carter also gave advice to his successor."I would say to promote human rights, to keep our country at peace, and to tell the truth," Carter said of his words of wisdom for Trump. "I would like to see the United States of America, I'd say once again, become the foremost champion of human rights on earth."At a separate town hall the night before, Carter slammed Trump's response to North Korea, saying the North Koreans needed to be treated with respect. He also cast doubt on Trump's ability to engineer peace in the Middle East.The 92-year-old lamented the extreme partisanship in government affairs, saying he believes the US is at its most fragmented since the Civil War. He also slammed the increase in lobbying and campaign contributions in contemporary elections."I would say the most serious threat to our democracy is making ourselves even more like an oligarchy," he said. "America ... used to be one of our finest democracies on Earth and as I said, it's become primarily an oligarchy." 2800
President Donald Trump’s campaign is blasting Joe Biden’s vice presidential pick, calling Sen. Kamala Harris “phony.”In a statement, Trump adviser Katrina Pierson says Harris “will abandon her own morals, as well as try to bury her record as a prosecutor, in order to appease the anti-police extremists controlling the Democrat Party.”Pierson says Harris has “gleefully embraced the left’s radical manifesto, calling for trillions of dollars in new taxes and backing Bernie Sanders’ government takeover of healthcare.”Pierson calls Harris “proof that Joe Biden is an empty shell being filled with the extreme agenda of the radicals on the left.”For weeks, Trump’s campaign promised an aggressive response against whomever was selected by Biden as his running mate.Says Pierson, “At the ballot box, Americans will resoundingly reject the abysmal failures of Biden-Harris in favor of the America First strength of President Donald Trump and Vice President Mike Pence.”__4:17 p.m.Joe Biden has chosen California Sen. Kamala Harris as his running mate. It’s a move that fulfills the wish of Democrats clamoring to see a woman of color on a major party’s presidential ticket for the first time in history.The 55-year-old Harris was elected to the Senate in 2016 after serving as California’s attorney general. Harris competed against Biden for the Democratic presidential nomination but left the race before voting began as she struggled to raise money.One of Harris’ standout moments of her presidential campaign came at the expense of Biden, when she slammed his past opposition to school busing. 1601
President Donald Trump's former campaign manager is receiving treatment under Florida's Baker Act following a reported suicide attempt.Fort Lauderdale police confirm Brad Parscale is getting help under a law that allows the detention of a person in the midst of a mental health crisis.According to police, Parscale's wife called 911 on Sunday and indicated that her husband was armed and threatening to harm himself while barricaded inside their home.Parscale eventually surrendered to the police.Trump demoted Parscale following a rally this summer in Tulsa, Oklahoma. Prior to the event, Parscale indicated that the campaign had received millions of requests for tickets. However, Trump's rally took place in a half-empty arena.A Trump campaign spokesperson told CNN that the organization "loves him like family" and "will support him through this time." 864
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