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BEIJING, August 4 (Xinhuanet) -- Medtronic Inc. is giving Yale University a 2.5 million U.S. dollar grant to review the safety and effectiveness of its controversial spine treatment called Infuse Bone Graft, according to The Wall Street Journals Thursday.Under terms of the pact, the company will release to Yale and eventually the public what participants described as an unprecedented amount of clinical trial and other data. The university will select two research teams from other organizations to perform separate analyses of the data.The announcement comes in the wake of a paper in June in the Spine Journal. The paper revealed that several clinical studies of Infuse, conducted by surgeons with strong economic ties to Medtronic, failed to report serious complications that arose in the trials. The critical paper also found that many of the studies were designed in ways in favor of Infuse over a treatment given to a control group.Medtronic disputes some of the findings and is conducting an internal investigation of the matter.Infuse accounts for about 700 million dollars in annual sales for Medtronic. The product is under investigation by the Senate Finance Committee over the role payments to physicians who may have played how studies were reported.
UNITED NATIONS, Sept. 19 (Xinhua) -- Mohammad Hossein Niknam, acting minister of health in international affairs of Iran, said here on Monday that his country is working to prevent and counteract the non-communicable diseases (NCDs), which have had significant effect on the population."NCDs have traditionally been more prevalent in affluent societies," he said. "However, they are increasingly becoming common in many developing countries, and in particular among the less affluent groups. The Eastern Mediterranean Region (EMRO) as others is suffering a heavy burden of NCD diseases and Iran is no exception: the total burden of disease for NCDs is 45 percent for males and 33 percent for females."Niknam's statements came as he addressed the UN General Assembly High-Level Meeting on Prevention and Control of Non- communicable Diseases."This timely high-level event provides us with an ideal platform to share views, information, ideas and experiences, to come up with remedial proposals and to forge effective collaborative partnerships in the implementation of realistic but effective health development programs in common areas of concern pertaining to the non-communicable diseases," Niknam said.He explained that Iran is implementing a series of programs in order to reduce the frequency and impacts of NCDs."As part of these programs I would like to mention prevention and control of common NCDs risk factors, imposition of taxes to curtail unhealthy habits such as tobacco consumption, execution of mass public information and educational campaigns, fostering food industry regulations, screening of blood pressure levels and high glucosemia," he said.Iran has created a Non-Communicable Diseases Risk Factor Surveillance System, according to Niknam. This system, in place since 2004, has conducted six large-scale surveys to gather information helpful to public health."Further, comprehensive cumulative national data has been compiled based on age, sex and location to facilitate effective monitoring and implementation of policies geared towards control and prevention of NCDs," Niknam said.Iran is conducting many other integrated NCD control and prevention programs, such as, to name a few, a Cardiovascular Diseases Control Program for rural areas; a National Cancer Control Program focusing on breast and colorectal cancers; and a Diabetes Control and Prevention Program that targets both rural and urban areas.Niknam ended his statement by noting that Iran has held regional consultations on the NCD issue."I would like to conclude my remarks by mentioning that as a sign of its commitment to promote regional and international cooperation, the Islamic Republic of Iran hosted on 25-26 October 2010 in Tehran the first regional meeting of a series of the regional consultations held by WHO (World Health Organization) on the prevention and control of NCDs," he said. "In our understanding, only through closer and meaningful collaboration at all levels, especially in areas such as legislation, resource mobilization and information and knowledge sharing, we may success in our endeavor to prevent and combat NCDs."
WASHINGTON, Aug. 10 (Xinhua) -- After a journey of almost three years, NASA's Mars rover Opportunity has reached the Red Planet's Endeavour crater to study rocks never seen before, the U.S. National Aeronautics and Space Administration (NASA) announced on Wednesday.Scientists hope it will find rocks and terrain much older than any other that the itinerant robot has examined during its seven years on the red planet.The U.S. space agency said that Opportunity arrived at the rim of Endeavour on Tuesday. The golf cart-size rover is expected to remain at the 22-kilometer-wide crater for the next few years.A portion of the west rim of Endeavour crater sweeps southward in this color view from NASA's Mars Exploration Rover Opportunity."NASA is continuing to write remarkable chapters in our nation' s story of exploration with discoveries on Mars and trips to an array of challenging new destinations," NASA Administrator Charles Bolden said in a statement. "Opportunity's findings and data ... will play a key role in making possible future human missions to Mars and other places where humans have not yet been."NASA's Mars Reconnaissance Orbiter, which has been circling the planet since late 2005, detected clay minerals that form in wet conditions in the crater. Scientists want to find out if the minerals date back to Mars' distant past, when the planet is believed to have been wetter and warmer than the dry frozen desert it is today."We're soon going to get the opportunity to sample a rock type the rovers haven't seen yet," said Matthew Golombek, Mars Exploration Rover science team member, at NASA's Jet Propulsion Laboratory in Pasadena, Calif. "Clay minerals form in wet conditions so we may learn about a potentially habitable environment that appears to have been very different from those responsible for the rocks comprising the plains."NASA is searching for signs that Mars had a habitable environment billions of years ago. Knowledge of the Martian climate will be important to future manned missions there, and can shed light on the forces that shaped Earth's climate.NASA launched the Mars rovers Opportunity and Spirit in 2003 for what were planned to be three-month missions. But both continued operating well beyond that. Spirit stopped communicating in March 2010.
WASHINGTON, July 15 (Xinhua) -- Researchers at Mount Sinai School of Medicine have found that grape seed polyphenols -- a natural antioxidant -- may help prevent the development or delay the progression of Alzheimer's disease.The research, led by Giulio Pasinetti, was published online Friday in the Journal of Alzheimer's Disease, which causes brain changes that gradually get worse.This is the first study to evaluate the ability of grape- derived polyphenols to prevent the generation of a specific form of amyloid (A) peptide, a substance in the brain long known to cause the neurotoxicity associated with Alzheimer's disease.In partnership with a team at the University of Minnesota, Pasinetti and collaborators administered grape seed polyphenolic extracts to mice genetically determined to develop memory deficits and A neurotoxins similar to those found in Alzheimer's disease. They found that the brain content of the A*56, a specific form of A previously implicated in the promotion of Alzheimer's disease memory loss, was substantially reduced after treatment.Previous studies suggest that increased consumption of grape- derived polyphenols, whose content, for example, is very high in red wine, may protect against cognitive decline in Alzheimer's. This new finding corroborates those theories."Since naturally occurring polyphenols are also generally commercially available as nutritional supplements and have negligible adverse events even after prolonged periods of treatment, this new finding holds significant promise as a preventive method or treatment, and is being tested in translational studies in Alzheimer's disease patients," said Pasinetti.In Alzheimer's disease, brain cells degenerate and die, causing a steady decline in memory and mental function.