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Scans of the lungs of the sickest COVID-19 patients show distinctive patterns of infection, but so far those clues offer little help in predicting which patients will pull through. For now, doctors are relying on what’s called supportive care that’s standard for severe pneumonia.Doctors in areas still bracing for an onslaught of sick patients are scouring medical reports and hosting webinars with Chinese doctors to get the best advice on what works and what hasn’t.One thing that’s clear around the globe: Age makes a huge difference in survival. And one reason is that seniors’ lungs don’t have as much of what geriatrics expert Dr. Richard Baron calls reserve capacity.“At age 18, you have a lot of extra lung capacity you don’t use unless you’re running a marathon,” explained Baron, who heads the American Board of Internal Medicine. That capacity gradually declines with age even in otherwise healthy people, so “if you’re an old person, even a mild form can overwhelm your lungs if you don’t have enough reserve.”Here’s what scientists can say so far about treating those who become severely ill.HOW DOES COVID-19 HARM THE LUNGS?The new coronavirus, like most respiratory viruses, is spread by droplets from someone’s cough or sneeze. The vast majority of patients recover, most after experiencing mild or moderate symptoms such as fever and cough. But sometimes the virus makes its way deep into the lungs to cause pneumonia.Lungs contain grapelike clusters of tiny air sacs called alveoli. When you breathe, oxygen fills the sacs and passes straight into blood vessels that nestle alongside them. Pneumonia occurs when an infection -- of any sort, not just this new virus -- inflames the lungs’ sacs. In severe cases they fill with fluid, dead cells and other debris so oxygen can’t get through.If other countries have the same experience as China, about 5% of COVID-19 patients could become sick enough to require intensive careHOW DOES THAT DAMAGE APPEAR?Doctors at New York’s Mount Sinai Health System analyzed 121 chest CT scans shared by colleagues in China and spotted something unusual.Healthy lungs look mostly black on medical scans because they’re full of air. An early infection with bacterial pneumonia tends to show up as a white blotch in one section of one lung. Pneumonia caused by a virus can show up as hazy patches that go by a weird name -- “ground glass opacities.”In people who get COVID-19 pneumonia, that haze tends to cluster on the outside edge of both lungs, by the ribs, a distinctive pattern, said Dr. Adam Bernheim, a radiologist at Mount Sinai.As infection worsens, the haze forms rounder clusters and gradually turns more white as the air sacs become increasingly clogged.HOW TO TREAT THE PNEUMONIA?There are no drugs so far that directly attack the new coronavirus, although doctors are trying some experimentally, including an old malaria treatment and one under development to treat Ebola.“The best treatment we have is supportive care,” said Dr. Aimee Moulin, an emergency care physician at the University of California Davis Medical Center.That centers around assistance in breathing when the oxygen levels in patients’ blood starts to drop. For some people, oxygen delivered through a mask or tubes in the nose is enough. More severely ill patients will need a breathing machine.“The goal is to keep the person alive until the disease takes its course” and the lungs begin to heal, explained Mount Sinai’s Dr. Neil Schachter.The very worst cases develop an inflammatory condition called ARDS -- acute respiratory distress syndrome — that floods the lungs with fluid. That’s when the immune system’s attempt to fight infection “is going crazy and itself attacking the lung,” Baron explained.Many things besides the coronavirus can cause the condition, and regardless of the cause, it comes with a high risk of death.WHAT ELSE IS IMPACTED?Severe pneumonia of any sort can cause shock and other organ damage. But in a webinar last week, Chinese doctors told members of the American College of Cardiology to watch for some additional problems in severe COVID-19, especially in people with heart disease. The worst off may need blood thinners as their blood starts to abnormally clot, and the heart itself may sustain damage not just from lack of oxygen but from the inflammation engulfing the body.Another caution: The sickest patients can deteriorate rapidly, something a hospital in Kirkland, Washington, witnessed.Of 21 patients who needed critical care at Evergreen Hospital, 17 were moved into the ICU without 24 hours of hospital admission, doctors reported last week in the 4639
Senate Minority Leader Chuck Schumer put forth a number of amendments to rules set forth by Majority Leader Mitch McConnell, setting the table for President Donald Trump's removal trial over the next few weeks. All 11 amendments put forth so far on Tuesday have been tabled -- effectively turning them down -- by a party-line vote in all but one vote. Fifty-three Republicans voted to table the amendments, while 47 Democrats voted against tabling in 10 of the 11 votes. The only exception was on Amendment No. 1293 when Republican Susan Collins voted against tabling the motion.McConnell said at the onset of Tuesday's session that the GOP would block votes on all amendments to the rules put forth by him. "If a senator moves to amend the resolution in order to subpoena specific witnesses or documents, I will move to table such motions because the senate will decide those questions later in the trial," McConnell said. But Schumer continued on with a series of amendments. "These amendments are not dilatory," Schumer said. "They only seek one thing, the truth. That means relevant documents, relevant witnesses. That's the only way to get a fair trial and everyone in this body knows it. All 15 that were brought to completion feature witnesses, every single one. The witnesses we request are not Democrats. They're the president's own men."Here is what the Senate has voted on so far today:Amendment No. 1284This amendment would have compelled documents via subpoena from the White House to be used in the Senate trial. Amendment No. 1285This amendment would have compelled documents via subpoena from State Department to be used in the Senate trial. Amendment No. 1286This amendment would have compelled documents via subpoena from the Office of Budget and Management to be used in the Senate trial.Amendment No. 1287This amendment would have issued a subpoena for the testimony for White House Chief of Staff Mick Mulvaney.Amendment No. 1288This amendment would have compelled documents via subpoena from the Department of Defense to be used in the Senate trial.Amendment No. 1289This amendment would have issued a subpoena for the testimony for White House aide Rob Blair and Office of Budget and Management official Michael DuffeyAmendment No. 1290This amendment would have prevented the selective admission of evidence and to provide for appropriate handling of classified and confidential materialsAmendment No. 1291This amendment would have issued a subpoena for the testimony for former National Security Adviser John Bolton.Amendment No. 1292This amendment would have required motions to subpoena witnesses or documents shall be in order after the question period.Amendment No. 1293This amendment would have given additional time for House managers and Trump's legal team to file their responses to motions.Amendment No. 1294This amendment would have required Chief Justice Roberts to rule on motions to subpoena witnesses and documents.The documents requested by Democrats would have included emails, text messages, notes and other communications between White House and other government officials.After nearly 13 hours, the Senate finally voted to approve rules put forth by McConnell to lay out rules and a schedule for the trial. One point of contention was on the schedule for arguments. Originally, McConnell proposed 48 hours of opening arguments, 24 hours by the two respective legal teams, split over four days. After some criticism from Democrats, McConnell altered his proposal to splitting the arguments over six days, giving each team three days each.Another was on how evidence would be accepted by the Senate. 3652

Quest Diagnostics says nearly 12 million people could have been affected by a data breach that includes their personal information, certain financial data, Social Security numbers and medical information.According to the company, American Medical Collection Agency informed Quest that an unauthorized user had access to AMCA's system containing personal information they received from various entities, including Quest.AMCA provides billing collection services to Optum360, which is a Quest contractor.According to Quest, AMCA first notified them May 14 of potential unauthorized activity on the AMCA web payment page, and on May 31, they notified them that the data included information on about 11.9 million Quest patients.AMCA has not yet given detailed or complete information about the data breach to Quest or Optum360, the company said, including which information of which individuals may have been affected. Quest has not also been able to verify the accuracy of information received from AMCA, they said."Quest is taking this matter very seriously and is committed to the privacy and security of our patients’ personal information. Since learning of the AMCA data security incident, we have suspended sending collection requests to AMCA," the company said. 1277
San Francisco will become the first US city to effectively ban e-cigarette sales, after the city's board of supervisors voted in favor of an 153
Special counsel Robert Mueller's deputy Aaron Zebley is expected to appear next to the special counsel as his counsel at Wednesday's hearings on the 161
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