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SAN DIEGO (KGTV) - Two construction workers were injured after being dragged into a ditch in a bizarre hit-and-run incident in the Bay Ho area. 151
SAN DIEGO (KGTV) - UC San Diego School of Medicine researchers believe they have discovered a way to reduce what they describe as health risks associated with red meat. A study published Monday in the journal Nature Microbiology considers whether bacterial enzymes could be used to clear from our tissues a carbohydrate created when humans eat red meat. The carbohydrate, known as Neu5Gc, builds up as we eat red meat, researchers say. They suggest our immune systems treat Neu5Gc as a foreign invader and generate antibodies against it, leading to chronic inflammation and other diseases. A team led by UC San Diego professor of pediatrics and bioengineering Karsten Zengler, Ph.D., believes bacterial enzymes could remove Neu5Gc from red meat before people eat it. “It’s our hope that this approach could be used as a sort of probiotic or prebiotic to help reduce inflammation and the risk of inflammatory diseases - without giving up steak,” said Zengler. The researchers bought steak and pork sausage from a grocery store and rubbed it with a lab-made bacterial enzyme. They found that “sure enough, most of the Neu5Gc came right off,” according to UC San Diego officials. Zengler and his team are working to optimize the enzyme to make sure it removes Neu5Gc and not similar carbohydrates. The group will also explore mass production possibilities and the potential for preventing inflammation and inflammatory diseases.The study was funded by the National Institutes of Health, National Science Foundation, UC San Diego Chancellor’s Research Excellence Scholarship, and Science Without Borders, officials said. 1624
SAN DIEGO (KGTV) — Whether or not the Padres head to the World Series, Petco Park may still see playoff baseball this season.Under a plan by the MLB, a neutral-site playoff format with teams living in a "bubble" may be finalized next week, though it is awaiting approval by the Players Association, according to ESPN.The plan states that playoffs would start with the top four seeds in the AL and NL hosting all the games in a best-of-three wild-card series: the AL games between Sept. 29 and Oct. 1 and the NL games between Sept. 30 and Oct. 2.The highest AL seed would be the home team for the division series at Petco Park in San Diego, while the other series heads to Dodger Stadium in Los Angeles. The AL championship series would then be played at Petco Park.On the NL side, the top seed into the division series would play at Globe Life Field in Arlington, Texas, and the next-highest seed would play at Minute Maid Park in Houston. The NL championship series would be hosted in Arlington.The MLB's reported plan would begin the World Series on Oct. 20 at Arlington and end no later than Oct. 28.ESPN reports that the Players Association is considering concerns from players who have lived outside of the bubble format, similar to how the NBA has operated this season, with the ability to be around family and friends. Inside the proposed playoff plan, teams would operate in a bubble to prevent exposure between players, staff, and others. 1455
SAN DIEGO (KGTV) -- We've all seen the nasal swabs being pushed far up noses to test for coronavirus. And if you've had it done, you know it's uncomfortable. But more tests are being developed where all you have to do is spit into a tube."You basically open up your mouth, we collect a tiny bit of saliva and you're done. Your side is done," said Dr. Henry Ji, President and CEO of San Diego based Sorrento Theraputics.According to Ji, the biopharma company is on track to start producing a rapid saliva test developed by researchers at Columbia University.It's being called "COVI TRACE" and it can be used almost anywhere.It gives results in about 30 minutes, with the liquid color changing from red to yellow if it's positive for Covid-19.Preliminary results indicate the test has high accuracy rates.Sorrento also says "COVI TRACE" is highly sensitive, meaning it can detect the presence of Covid-19 very early on.Sorrento executives say they plan to submit the test for FDA approval within the next few weeks."While the FDA is reviewing and leading up to review we are gearing up to manufacture hundreds of thousands and millions of tests; eventually anticipating about a hundred million tests a month," said Sorrento's Henry Brunswick.As for the cost, Ji says they're trying to keep it widely affordable, at around .At this point there's no estimate for when the rapid saliva "COVI TRACE" test could be approved by the FDA, but Sorrento is submitting an emergency use request in hopes of speeding up the process. 1528
SAN DIEGO (KGTV) — UC San Diego Health and three other UC Health medical centers will begin to recruit participants for an antiviral drug being tested to treat the novel coronavirus.The medical system will start "phase II" clinical trials for the antiviral drug remdesivir. The drug has "shown activity in animal models and human clinical trials of SARS-CoV, MERS-CoV, Ebola, Marburg and other viruses," according to UCSD Health.RELATED: San Diego hospitals start drives for personal protective equipmentRemdesivir is not currently approved for the treatment of any infection by the FDA, but is currently undergoing trials for treating multiple viruses, including COVID-19.“With this type of adaptive study design, if remdesivir proves to be safe and active, the clinical trial may be rapidly adapted to remove the requirement for a placebo arm and add a treatment arm that includes other promising antiviral or other investigational drug to compare with the activity of remdesivir," said co-principal investigator Constance Benson, professor of medicine at UC San Diego School of Medicine and an infectious disease specialist at UC San Diego Health.RELATED: Nurse urges people to turn over N95 masks to San Diego hospitalsUC San Francisco, UC Irvine Health, and UC Davis Health are also participating in the trials. The trial is projected to run until April 1, 2023 and involve 440 participants. 1404