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A final analysis of a COVID-19 vaccine candidate produced by Pfizer and BioNTech shows that the drug is 95% effective in preventing the coronavirus, and the companies say they hope to apply for Emergency Use Authorization within "days," the company reported Wednesday.The announcement is an improvement from an initial analysis released by the company just over a week ago that showed the drug to be 90% effective. Those results were released when it had been confirmed that 94 participants in the trial who received a shot had contracted COVID-19, and only 10% of those participants who contracted the virus had actually received the vaccine. Updated information now shows that 170 people who participated in the trial have contracted COVID-19, which crosses the threshold for final analysis. Of those participants, 162 received a placebo shot. Of the 20,000 participants who received the vaccine, just one has developed a severe case of COVID-19. The other seven people who received the vaccine and caught the virus are only experiencing mild symptoms.Pfizer also added that the vaccine has proven to be 94% efficient in older people — a welcome sign, given that the virus tends to present more severe symptoms in elderly patients.Pfizer's trial included about 40,000 participants, half of which received the vaccine, and the other half which received the placebo. The vaccine requires two shots, which need to be taken 28 days apart.The company added that there have been no safety concerns with the vaccine. In a randomized survey of 8,000 participants, only 2% reported suffering severe fatigue, and only 4% reported suffering severe headaches. Those who say they suffered side effects only experienced them briefly after vaccination.Wednesday's announcement means Pfizer is on track to shatter records for vaccine development, a process that typically takes several years.Pfizer and BioNTech already have their vaccine candidate in production, meaning it will be ready for distribution as soon as the Food and Drug Administration grants Emergency Use Authorization.Pfizer's announcement comes days after an initial analysis of a Moderna-produced vaccine was also shown to be 95% effective. Several other companies also have a COVID-19 vaccine in the works, something that health officials say is important for logistics and safety. 2347

A Cleveland family is hoping social media will help them locate the donor who provided bone marrow to treat their 2-year-old daughter’s cancer last October. Doctors say this anonymous donor could be the key to treating their daughter’s cancer relapse.G.I. and Annie Zaratsian’s daughter Viv is living a normal 2-year-old’s life – at home, enjoying time with her sisters. She was diagnosed with Acute Megakaryoblastic Leukemia on July 20, 2017, at just 18 months old, according to a Facebook post from her mother. Over the next five months, Viv was hospitalized, faced multiple challenging complications, and received a bone marrow transplant from an anonymous donor. One year after her diagnosis, she was in remission.Then, during a recent routine biopsy, Viv’s family learned that she is beginning to relapse, and her cancer is returning, her father said in a Facebook post on Tuesday. The biopsy revealed that 0.2 percent of her cancer cells are back.The family is working with doctors at the Rainbow Babies and Children’s Hospital in Cleveland to develop a plan to get Viv back into remission and fully healthy again, and to capitalize on the fact that her cancer numbers are still low, her father said.One of the potential treatments Viv’s doctors would like to administer is a process called Donor Lymphocyte Infusion, or DLI. It requires some of the blood to be extracted from her bone marrow donor and then infused into Viv, her father explained.Unfortunately, the donor registry team is unable to make contact with her bone marrow donor and the family is not legally allowed to receive information about who the donor is due to privacy and confidentiality regulations.The family posted all this on Facebook with the hope that it would be shared, and that the anonymous donor would come forward to donate his blood and get Viv the treatment she needs.The family knows the donor is a young male, likely 20 to 30 years old, and he does not live in the United States. There’s another unique connection that might help them track him down: when he donated his bone marrow, he sent along a small blue sheep figurine for good luck.Since it was posted Tuesday afternoon, G.I. Zaratsian’s post received over 4,000 shares and over 246 comments, as of Wednesday morning. The post is embedded below if you’d like to share it with your Facebook friends. 2356

A Lake Geneva, Wisconsin teenage who was stuck in Paris for weeks after falling into a coma has returned to the United States, his family says.Nathan Dyer returned to the US late Wednesday morning. His family is still raising money to pay off  thousands in medical bills.About a month ago, Dyer embarked on his first journey overseas to Morocco with his cousin. Dyer got sick a week into the vacation and fell into a coma. He was air-lifted to Paris for better care."There were times where I felt completely helpless and had no idea what to do," Dyer's sister said.  As days pass, Dyer said her brother still doesn’t have a diagnosis. 657

A father of two young children found dead inside a hot truck was released on bond after the Tulsa District Attorney's Office said surveillance video shows the children got into the car on their own.The district attorney said in a statement that video from a neighbor's home confirmed the two young children got into the truck on their own and never got back out.The DA's office issued the following statement on Monday: 427

A man has died in Alabama as a result of Hurricane Sally, according to several media outlets.The Weather Channel reported the unidentified man died in Orange Beach, Alabama.Orange Beach Mayor Tony Kennon confirmed to WVTM that a person is missing.The National Hurricane Center reported that the slow-moving storm made landfall near Gulf Shores, Alabama, on Wednesday at 5:45 a.m. ET with maximum sustained wind speeds of 105 mph. 437