中山做个痔疮手术大概多少钱(中山华都肛肠医院线上医生免费咨询) (今日更新中)

SAN DIEGO (KGTV) — The National Institutes of Health highlighted research Tuesday out of UC San Diego that could unlock a new way to treat COVID-19.The research reveals new insight into how the coronavirus hijacks cells, and how doctors might be able to set traps or decoys to combat the virus. The findings were published in the journal Cell last month.“It does open up another avenue for a potential treatment,” said UC San Diego distinguished professor Dr. Jeffrey Esko. “It’s not a cure. It would be something that would tamp down infection potentially.”Since January, scientists around the world have understood that SARS-Co-V2, the official name of the new coronavirus, enters cells by latching onto a specific receptor on the cell’s surface, called ACE2.The UCSD team, led by Dr. Esko and visiting scholar Dr. Thomas Clausen, discovered that this entry mechanism is actually a two-step process, and the virus must also attach to a long chain of sugars called heparan sulfate.“We’ve shown this is fundamental to the infectious mechanism, so it needs to be part of every study from now on,” said Clausen.All cells are coated with a complex layer of sugars, or carbohydrates, called glycans. Heparan sulfate is one type of glycan that is known to play a key role in the infection process in several viruses, including herpes and other coronaviruses.It’s a complicated process to picture so the researchers offer an analogy: imagine a bird, soaring over trees, hunting a worm on the forest floor. The bird is the coronavirus and the trees are the thick layer of glycans that coat the surface of the cell.To reach the worm, which in this case is the receptor ACE2, the bird must navigate its way through the trees, specifically through heparan sulfate.The UCSD found that by removing the heparan sulfate trees with an enzyme, they were able to prevent the virus from infecting cells. In laboratory testing, they also found a second technique worked to foil the virus: introducing more trees as bait.The team found that heparin, an FDA-approved drug that is similar in structure to heparan sulfate, successfully acted as decoy. Heparin is a widely used drug designed to treat blood clots. Since blood clots and strokes are common complications with COVID-19, many doctors already administer heparin to patients.The UCSD team demonstrated that the two approaches can block infection in lab-grown cells about 80 to 90 percent of the time.“Certainly in the laboratory you can demonstrate that it works, but to deploy it and use it as a therapeutic has not been demonstrated,” Esko said.The NIH noted that more studies are planned to explore whether heparin, heparan sulfate, or drugs that target heparan sulfate might yield a viable COVID-19 treatment.Dr. Esko said he’s already been in talks with companies that plan to use their study as a rationale for a clinical trial.“It is very humbling when you realize we’re working on a pandemic right now, and maybe what we’ve done can contribute to a treatment for the disease,” he said. 3038

SAN DIEGO (KGTV) -- Summer is just around the corner, and that means it's almost time to break out the swimsuit. Thankfully for anyone trying to get swimsuit-ready, there are plenty of health-conscious restaurants in San Diego to choose from. Check out the list below of top-rated vegan restaurants in San Diego, according to Yelp:  355

SAN DIEGO (KGTV) -- The 10News team is celebrating the return of morning reporter Marie Coronel."I'm so glad to be back here with you guys," she told the morning 10News team in an emotional appearance in the studio Wednesday.About three and half years ago, Marie and 10News photographer Mike Gold were in Mira Mesa preparing for a live report on storm damage when heavy branches snapped off a massive eucalyptus tree crushing the both of them. Mike was able to recover from his injuries and was back to work a few months later, but it's taken years for Marie to recover from multiple injuries and return to the newsroom."This has been a crazy long journey...it's been so tough emotionally, physically, and me going through physical therapy, then doing all of this while raising our three little boys," she said.During her recovery, the native San Diegan stayed active and connected in the community through social media. But Marie acknowledged that her return was met with some jitters when 10News anchor Jim Patton asked what it felt like to be back."I was like the new kid walking in yesterday but then now in day two I'm like, 'let's get back to business.'"Marie credits her recovery and perseverance to the enormous support from family, friends, faith, co-workers, and the 10News – ABC San Diego KGTV viewers, she said."I’ve kept my eyes and ears on our community, and there are so many stories I can’t wait to start reporting. I’m thrilled to be back with our 10News team and telling your stories," Marie posted on her 10News Facebook pageFollow Marie Coronel at https://www.facebook.com/MarieCoronel10News/. 1622

SAN DIEGO (KGTV) - The California Highway Patrol said a person arrested at gunpoint on Interstate 15 in San Diego Thursday was suspected of driving illegally in the HOV lane and leading an officer on a pursuit.The chase happened on southbound I-15 just south of Aero Dr. at 5:30 p.m.Officers said the driver was in the high-occupancy vehicle lane and failed to pull over, leading to the brief pursuit.There are no reports of any injuries or a reason why the driver did not yield for the traffic stop. 508

SAN DIEGO (KGTV) - The memories came flooding back for Vietnam veteran Ray Hildreth as he returned to Camp Pendleton 50 years later. He wanted to tour his old unit, the 1st Recon Battalion."Looking at the mountains, I remember having to run up and down them!"And while the current 1st Recon Battalion Marines may not recognize Hildreth, they know his story. In June of 1966, Hildreth's unit was stationed on Hill 488 in the jungles of Vietnam. Before the week was over, they would fight the battle that would make them the most highly decorated small unit in the entire history of the U.S. military, winning a Congressional Medal of Honor, four Navy Crosses, thirteen Silver Stars, and eighteen Purple Hearts—some of them posthumously.There were just 18 of them when they encountered the enemy, a battalion of over 200. "Early on in the battle, and all the Marines here can identify with this, the NVA yelled out 'Marines you die in an hour,' and we had some colorful words to say back to them, and said, come and get us," remembers Hildreth.The late Staff Sergeant Jimmie Howard served as platoon leader with 1st Reconnaissance Battalion and led the defense of Hill 488 when attacked by the North Vietnamese.Howard had combat experience from Korea, and Hildreth credits the leader with keeping them alive. "Sergeant Howard said, 'Laugh at them!' And we did, we laughed out loud at them. Later I went back to Vietnam, 2011. I met one of the NVA we fought against. I asked him, what did you think when we laughed at you? He said we thought you were a much bigger unit. And it was that laugh, I'm sure of, that made them not just try to walk over the top of the hilltop and take us," said Hildreth. When they were out of grenades, the men began throwing rocks. "If we hadn't laughed at them, by sheer numbers, they could've walked across the top of the hill and killed us. At the end of the day, there were maybe eight rounds of ammunition left between us."The unit killed an estimated 200 people.Of the 18, all were wounded, and six died. Hildreth wrote a book about the battle, titled Hill 488."I thought people needed to know about the battle, not everyone went over there took drugs and smoked pot," said Hildreth. "We went over there with a different outlook, we're supposed to be here, there's a reason for it, and we done our job. We didn't protest."During the visit, Hildreth was accompanied by some of Staff Sergeant Howard's family members. 2456

来源：资阳报