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SAN DIEGO (KGTV) -- The first Tuesday of every August, people across the nation recognize National Night Out.The night is designed to strengthen neighborhood spirit and police-community relations and heighten crime and drug prevention awareness.Thousands of people throughout the county are expected to attend this year’s National Night Out.Check out the list below for locations: 388

SAN DIEGO (KGTV) — The crowds at San Diego International Airport grew Friday night, as travelers kicked off the holiday travel weekend. AAA predicts a record-breaking 115 million Americans will travel this holiday season, up nearly 4 percent from last year. Of those travelers, AAA estimates 105 million people will drive, 7 million will fly, and 4 million will take the train, bus, or cruise ships. According to AAA, airports around the US will be busiest between Dec. 21 through 23. But the crowds should start to build Friday.RELATED: This holiday season to set travel records, AAA says10News spoke to many travelers going in and out of San Diego International Airport Friday. Melissa Flatley flew in from Reno, Nev. She said she wore her festive antler headband to make sure her sister does not lose her in the crowd."It's a little busy on a holiday weekend, so I just wanted for her to find me a little more easily!" Flatley laughed. 10News also met the Monje family. The San Diego family of five was headed to Jacksonville, Fla., to visit family. They said they were travel pros, who purposely wait until the last second to fly, thanks to father Joel's job at Southwest Airlines. RELATED: AAA provides tips on preparing vehicles for holiday travel"We fly standby, so it's always a little frazzled and anxious for us," Lisa Monje said. "But we're very thankful for our benefits. If we can get there on standby for free, hey, that's even better!"Carlos Yu flew in from El Paso, Texas. He told 10News he's glad to be back home in Southern California and planning to take every form of transportation to make his rounds to see friends and family."I've actually never taken the train, so I'm super excited about that," Yu said. "I'm going to drive back down, actually again, so it's going to be a good two weeks."RELATED: The holidays bring a spike in heart attacks. Here's why10News also met the Smith family, who was waiting for their two sons to come home. Their father, Joshua, is in the Navy, based in San Diego. Older brother, Malik, is in the Army. He flew in from El Paso. Middle brother, Jauan, is in the Air Force. He arrived from San Antonio. They all came together from bases all over the country to spend the holidays together at home. "I literally cannot come home to see them until I have to leave to come and do it, so it means a lot. We all get together. It doesn't happen all the time," Jauan said. Santa and Mrs. Claus made an appearance to make sure travelers had a festive and stress-free experience at the airport. 2546

SAN DIEGO (KGTV) — The Department of Defense has awarded a San Diego biotech company up to million to help develop a next-generation drug to fight COVID-19.Sorrento Therapeutics calls the drug a “rapid countermeasure” against the disease, one that might serve as a vaccine substitute in certain populations or a critical stopgap tool if the virus mutates.“With this, we have a new platform potentially that can respond very quickly to any type of emerging threat,” said CEO Dr. Henry Ji.Sorrento is trying to become the first company to develop an approved DNA-encoded monoclonal antibody treatment. The approach is similar to the experimental monoclonal antibody treatment used on President Trump, but Sorrento’s concept is a more advanced version that offers several benefits.Sorrento’s drug is designed to be used as either a treatment in infected patients or a fast-forming layer of defense in healthy people. The company said its solution should be cheaper and easier to deploy than existing monoclonal antibodies, while offering vaccine-like protective effects that last for several months rather than just two or three weeks.Antibodies are one of the body’s key defense mechanisms. They seek out pathogens and bind to them, marking the invader for destruction like ground troops marking an enemy base for an airstrike. In some cases, antibodies can even neutralize an invader themselves by blocking its method of entry into cells.Monoclonal antibodies are antibodies designed by scientists to neutralize a pathogen. They are hand-picked, genetically modified super antibodies that are cloned in labs.However, the process of growing these super soldiers in the lab is difficult, transporting them requires a cold chain, and as a result, monoclonal antibodies are among the most expensive drugs in the world.Instead of giving people an infusion of pre-made antibodies, Sorrento’s idea is to give people a shot of DNA that instructs some of their cells to churn out perfectly pre-designed antibodies.“It's much easier to make enough DNA to treat a large number of people than it is to make enough protein to treat a large number of people. That’s just a fact about manufacturing,” said Dr. Robert Allen, Sorrento’s chief scientific officer on the project.Dr. Allen said the company is hopeful the drug will induce cells to make protective antibodies for six months or more.This DNA approach to an antibody treatment has never been approved for any disease but other companies are working on their own versions of it. Another biotech with ties to San Diego, Inovio Pharmaceuticals, became the first company to test this approach in humans in 2019 for a drug targeting the Zika virus.Sorrento’s approach is similar to the way DNA vaccines work, but it cuts out intermediary steps and jumpstarts the production of antibodies, rather than leaving the production of antibodies up to the body’s immune system. The result is that protective antibodies can start circulating in days after injection rather than weeks, the company said.“What this is capable of doing is it bypasses the need for the immune system,” said Dr. Mark Brunswick, Sorrento’s senior vice president for regulatory affairs.The drug is unlikely to replace a vaccine in most situations because vaccines can produce other defense mechanisms like T-cells that work in conjunction with antibodies. But the drug might work better than a vaccine for the elderly and others with weakened immune systems who are unable to produce a robust number of antibodies on their own, Brunswick said.Still, the company still has a lot of pre-clinical work and testing to go. Sorrento is hoping to have the drug ready for human trials in four to six months.By then, vaccines from Pfizer and Moderna will likely be widely available, but Dr. Ji said the world needs to prepare for the possibility this virus will mutate.“When you vaccinate hundreds of millions, potentially billions of people, the virus is under tremendous evolution pressure,” he said. “It will escape. It’s guaranteed that the virus is going to mutate and escape all of the vaccines we’re trying to create.”If it does, he said Sorrento will be ready to rapidly deploy its DNA-based countermeasure. 4223

SAN DIEGO (KGTV) — Summer is right around the corner, San Diego.For younger San Diegans, that means week of adventure and learning at summer camp! And there's something for every interest around San Diego County. Whether it's a traditional day camp with fun activities or something specific (did someone say Circus Camp?)RELATED: Events to enjoy with your toddler in San DiegoHere's a look at a variety of camps — specialty or traditional — around the county this summer:Summer Critter CampWhere: Helen Woodward Animal Center; When: June 10 - Aug. 30Kids will get to experience animal encounters and summer camp activities, animal-themed games, crafts, songs, and get a free Critter Camp t-shirt.YMCA Overnight and Day CampsWhere: Various locations; When: June - AugustYMCA branches across San Diego County offer up a variety of day and overnight camps, from traditional to specialty, and camps just for sports, leadership, adventure, and more.Mesa Rim Climbing CampWhere: Mesa Rim locations; When: March - AugustKids can hit the ropes at Mesa Rim's two San Diego locations, learning yoga, top roping and bouldering skills, or enjoying non-climbing activities like a ninja obstacle course, scavenger hunts, and more.San Diego Zoo and Safari Park Summer CampWhere: San Diego Zoo and Safari Park; When: June - AugustCampers will get to enjoy a wide variety of animal adventures at the San Diego Zoo or Safari Park, with options for various grade levels and featuring a variety of exhibits, tours, games, crafts, and more.Girl Scout CampsWhere: Various locations; When: Various datesWhether or not your child is a Girl Scout yet, they can jump into summer day camps, resident camps, weekend camp outs and more, all featuring educational activities and leadership building fun. Circus CampWhere: San Diego Circus Center; When: June 17 - Aug. 9Kids will learn the fundamentals of circus arts at the San Diego Circus Center's summer camp. Everything from aerial tricks, tumbling, juggling, and clowning to help build strength, teamwork, and focus.Wildlife Day CampWhere: Living Coast Discovery Center; When: June 10 - July 26Campers will experience animal encounters, games, arts and crafts, outdoor exploring, and more while learning about wildlife, conservation, and science.Outside the LensWhere: Liberty Station; When: June 21 - Aug. 23Interested in photography? Kids can jump into a variety of digital media camps throughout San Diego County, designed to build photography and filmmaking skills, promote creativity, and encourage collaboration.Science Summer CampWhere: Fleet Science Center; When: June - AugustA variety of science-themed activities await covering STEAM topics, wildlife, energy and physics, coding, space, and much more through experiments and hands-on learning.Youth Programs at La Jolla PlayhouseWhere: La Jolla Playhouse; When: June - JulyChildren will take part in a series of interactive theatre training programs that cover acting, musical theater, stage movement, improvisation, or behind-the-scenes tasks like costumes and props, set design, and technician support. 3098

SAN DIEGO (KGTV) - The Gubernatorial Primary Election is on Tuesday, June 5. Voters who are interested in getting their ballots in before Election Day can now do so at the San Diego County Registrar of Voters office.Early voting began on Monday, May 6 after the United States Postal Service sent out more than 1 million mail ballots. These ballots appeared in voters' mailboxes the very same day.Early voting continues through Friday, from 8 a.m. to 5 p.m and until the polls close on Election Day at 8 p.m.The Registrar of Voters Office is open for weekend voting from 8 a.m. to 5 p.m. on Saturday, June 2 and Sunday, June 3. Registered voters can also request a mail ballot until May 29 if they do not wish to vote in person.The Registrar of Voters Office is located at 5600 Overland Avenue on the County Operations Center campus in Kearny Mesa. 855