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LA JOLLA, Calif. (KGTV) - A researcher at UC San Diego just got a million grant to further his work into nanosponge therapy.Liangfang Zhang, a professor of nanoengineering and bioengineering, has been working on creating macrophage cellular nanosponges, tiny particles covered in white blood cell membranes, to treat sepsis and other diseases."They can be used to bind to the virus and neutralize the virus," Zhang says. "So now the virus would lose the ability to infect the host cells."The nanosponges act as decoys, tricking a disease or virus into binding with them instead of with human cells. While the initial aim is to treat sepsis, Zhang says it has applications to other deadly diseases, including COVID-19."The formulation that we're developing for treatment of Sepsis is the same formulation that you will use with COVID-19," he says.The grant comes from CARB-X, a Boston-based medical philanthropy that specializes in funding research into antibacterial treatments. Zhang says the money will be used for his company, Cellics Therapeutics, to further advance the research into clinical trials, FDA approval, and production of the nanosponge therapy.Steve Chen, president and chief medical officer of Cellics Therapeutics, says he's hopeful they can advance the nanosponges into human trials within two years."We're essentially looking at how this platform can treat not just infectious disease or future pandemics, but you could actually have a lot of applications in any type of autoimmune diseases or any type of inflammatory diseases," says Chen.In an early study published this year, Zhang's research showed the nanosponges were around 90% effective at blocking infections from taking hold.RELATED: UC San Diego researchers testing nanosponges to fight COVID-19Chen says the research and trial period may take too long for the nanosponges to be used during the current coronavirus pandemic. But he's hopeful it will help make the next outbreak less severe."My sincere desire is that we are not going to need this for COVID-19. But I think this does position us very well for any potential future kind of viral outbreak," says Chen.Cellics is also working on a Red Blood Cell version of their nanosponges, which may be ready for human trials within a year. 2283

KANSAS CITY, Mo. --  Most people quit their jobs by submitting a resignation letter or simply not showing up, but one local man is going viral for the unique way he quit at an area Popeyes.Cedrick Workuff grabs a microphone before he heads into the Popeyes near 103rd and State Line Rd. Tuesday afternoon. "I come in here and slave all the time," he says in the now-viral video. "They think I'm going to go in there and be like 'I quit, I quit.' No, I'm about to go in there and sing."Followed by his friend, Marco Summers, who is recording on his phone, Workuff grabs a microphone and heads to the door. "Excuse me, sir," Workuff said as he squeezes past a customer at the door. "I'm about to quit my job today." In the next few minutes, Workuff improvises a catchy song as the chuckling customers and confused employees stare on. Since the video was posted Tuesday afternoon, it's earned over 72800 views and nearly 13,000 shares. So what's the story behind the viral video? In an interview with 41 Action News, Workuff revealed he didn't even work at the Popeyes in the first place. Summers says he made the video to spread positivity and make people laugh."It's something me and Marco wanted to put in the works," said Summers. "It wasn't planned. It was all improvised. Only the idea was planned." Summers says he's made several other videos that have been shared by celebrities and TV shows like 'Right This Minute.'He gets his inspiration from his own experiences."I've been through most of the stories I talk about. Instead of letting them damage me, I make them something funny," Summers said. "It's opening a door for people to laugh at situations like that."Summers and Workuff hope to someday turn their stories into a TV show. "If we don't make people smile, we failed," Summers said. "Our main missing is to bring back peace and love through laughter," Workuff said. Summers posts videos on his Facebook and Youtube.  **Please be aware - this video does contain some explicit language.  2098

Just some lucky ducks.After a call from a man who saw a momma duck quaking for help near a street drain grate, Charles County officers came to the rescue.It appeared that the momma duck was hysterically quacking because all nine of her baby ducks had fallen into the drain and could not get out.That's when Charles County Officer Mohler opened the gate on one side while Officer Coulby guarded the other side to save the ducklings. They were able to get five of the baby ducks out of the hole but struggled to get the others.A good Samaritan named Chad Marshell intervened and saved the day as he crawled 200 feet in the hole to guide the other baby ducks toward Mohler.All of the nine ducklings were reunited with their momma duck. 770

JAMUL (CNS) - A small plane landed in thick grass southeast of Jamul Casino in Jamul Wednesday night, but no one was injured.Deputies received a call of a downed plane about 7:50 p.m. off Campo Road, according to Lt. Glen Twyman of the San Diego County Sheriff's Department. The type of plane was not released.It was not immediately clear if the plane made an emergency landing or crashed, but neither occupant was injured.Fire crews remained on scene after the crash to prevent any of the nearby dry grass from catching on fire, Twyman said. 550

Kentucky Speaker of the House Jeff Hoover resigned from his position Sunday amid sexual harassment allegations, saying he had made "mistakes."Hoover, who The Courier-Journal newspaper in Louisville reported had secretly settled a sexual harassment allegation by a woman on his legislative staff, did not resign as a state representative, however, and has denied all allegations."I did make mistakes, in that I engaged in inappropriate text messages," the Republican lawmaker said at a press conference announcing his decision. "I engaged in banter that was consensual, yet make no mistake, it was wrong on my part to do that. And for that I am truly sorry."The Courier-Journal was the first to report Hoover's settlement last week, citing sources with direct knowledge of the matter. The settlement involved three other Republican state representatives and Hoover's chief of staff, the newspaper reported.Hoover and his accuser, whom the Courier-Journal has not identified because she says she was sexually harassed, declined to comment, as did a lawyer for the woman, the newspaper said.Hoover asked for the public's forgiveness in a tearful statement on Sunday, saying, "To say that the past few weeks and days have been trying and difficult for me and my family would be an understatement."Kentucky's House speaker pro tempore, Republican David Osborne, said in a statement that he will be assuming operational control of the chamber as acting speaker.Hoover's resignation comes a day after Kentucky Gov. Matt Bevin, also a Republican, called for "the immediate resignation of every individual who has settled a sexual harassment case, who is party to trying to hide this type of behavior."In a press conference Saturday, Bevin drew a "clear line in the sand for every elected official in Kentucky. These actions that have been alleged, not denied, and increasingly corroborated, and that are increasing in specificity and in number, were not isolated to a single person, or a single event, but involved multiple events and multiple people.""They know who they are, some have been named," Bevin said. "I would simply say this: For the sake of themselves, for the sake of their families and for the sake of Kentucky, they should resign. Period. The people of Kentucky deserve better than the type of shenanigans that have gone on for far too long in this town.""I expect the immediate resignation of everyone named," Bevin concluded.Hours after Bevin's speech, Hoover issued a statement that stopped short of confirming the Courier-Journal report."I am disappointed that our Governor in his press conference Saturday afternoon would call not only for my resignation but the resignation of other individuals who have no involvement in this matter," he said. "The governor has yet to ask our side of the story. He and I have not spoken since the story broke, and I did not receive a courtesy call from him before his grandstanding today. Instead, he has accepted as fact only, one side of the story.""In effect, the governor seeks to be judge, jury, and executioner without hearing the evidence," Hoover said, adding then that he had no plans to resign, and was "more resolved than ever to continue my work as speaker thru the 2018 session." 3264

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